Publications by authors named "Zhao-Lei Hou"
Article Synopsis
- The study assessed heavy metal accumulation in the soil-crop system of northeastern Yunnan, revealing high levels of cadmium (Cd) and lead (Pb) in certain areas, exceeding safety standards.
- The analysis of 1137 agricultural product samples highlighted significant exceedances of Cd in potatoes and soybeans, and Pb in tartary buckwheat and walnuts, with varying levels of contamination across different soil types.
- It concluded that while staple foods had low chronic health risks from heavy metals, there is an urgent need for ongoing monitoring of agricultural products due to potential health implications from contaminated areas.
Heavy metals (HMs) are naturally occurring elements that have high natural background levels in the environment. Therefore, it is important to conduct ecological risk assessment and identify potential sources of HMs. In the past, studies were conducted at the regional scale.
View Article and Find Full Text PDFBackground: Bone marrow derived mesenchymal stem cells (BMdMSCs) can differentiate into cardiomyocyte-like cells induced by different inductors individually or collectively. In this study, by inducing BMdMSCs with p53 inhibitor (p-fifty three inhibitor-alpha, PFT-α), 5-azacytidine (5-AZA), angiotensin-II (Ang-II) and bone morphogenic protein-2 (BMP-2) we compared the influences of four inductors on the differentiation of rat BMdMSCs into caridomyocyte like-cells.
Methods: BMdMSCs were collected from the bone marrow of Sprague Dawley rats and after the fourth generation, the purified cells were divided into five groups: 5-AZA (10 µmol/L), Ang-II (0.
Bone morphogenetic protein-2 (BMP-2) has a crucial role in the development of cardiogenesis, and is used in inducing bone marrow mesenchymal stem cells (BMMSCs) to differentiate into cardiomyocytes. We have examined a combination of BMP-2 and 5-azacytidine (5-AZA) in inducing these differentiation effects. BMMSCs were collected and purified from bone marrow of 4-week-old Sprague-Dawley (SD) rats by density-gradient centrifugation and differential attachment.
View Article and Find Full Text PDFObjective: To review the progress of cardiac differentiation and electrophysiological characteristics of bone marrow mesenchymal stem cells.
Data Sources: The databases of PubMed, Springer Link, Science Direct and CNKI were retrieved for papers published from January 2000 to January 2012 with the key words of "bone marrow mesenchymal stem cells, cardiac or heart, electrophysiology or electrophysiological characteristics".
Study Selection: The articles concerned cardiac differentiation and electrophysiological characteristics of bone marrow mesenchymal stem cells were collected.