Three new compounds named tanshinoic acid A (), tanshinoic acid B (), and tanshinoic acid C () were isolated from the rhizomes of , together with two known compounds methyl salvianolate A () and methyl salvianolate C (). Their structures were determined on the basis of spectroscopic data (UV, IR, HRESIMS, 1 D and 2 D NMR). The assay indicated that and could improve the survived rate of cells on oxygen glucose deprivation (OGD) induced neurons damage model and glutamate-induced neurons damage model at a concentration of 10 M.
View Article and Find Full Text PDFOne new tanshinone derivative, which possesses an unusual 6/6/5/6 fused-ring skeleton system (1), together with four new five-membered lactone benzohexa-membered ring compounds (2, 3, 4A and 4B), and three new carboxyl substituted 5,5-spiroketal compounds (5-7), were isolated from the dried rhizomes of . The structures of these compounds were determined by multiple spectral analyses (UV, IR, NMR, and HR-ESI-MS). In addition, the absolute configurations were established by X-ray diffraction experiments, calculated and experimental circular dichroism spectra.
View Article and Find Full Text PDFJ Asian Nat Prod Res
January 2020
Two new naturally occurring products named salviamine G (1) and 4-methyl-9-(ethoxycarbonyl)-8-naphthoic acid (2) were isolated from the rhizomes of . Their structures were elucidated using spectroscopic data (UV, IR, HRESIMS, 1D and 2D NMR). Compounds and were screened for their inhibitory activity against HSV-1 and influenza A (H3N2) using acyclovir (ACV, IC = 0.
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