(Crassulaceae), a new species from Zhejiang, East China.

In this paper, is described as a new species based on morphological and molecular analyses, and its taxonomic relationships are discussed. Morphological analysis indicates should be classified in the genus Sedumsect.Sedum and is distinct from the related species and in the morphology of its solitary, light green and smooth stems, flattened leaves, larger, obovate and spurless sepals, yellow anthers, 22-30 ovules per carpel, oblique follicles, and its habitat on shaded slopes or rocks.

Promoting structural distortion to enhance the crystal field strength of Mn(II) in tetrahedral bromide for near-unity yellow emission.

Two zero-dimensional hybrid manganese bromide polymorphs ((DMAPH)MnBr) exhibit single-crystal to single-crystal phase transformation, accompanied by an increase in MnBr tetrahedral bond angle variance (). This structural change leads to an emission redshift due to enhanced crystal field strength, achieving yellow emission with near-unity quantum yield, which highlights its potential for solid-state lighting applications.

Research progress of T cell autophagy in autoimmune diseases.

T cells, as a major lymphocyte population involved in the adaptive immune response, play an important immunomodulatory role in the early stages of autoimmune diseases. Autophagy is a cellular catabolism mediated by lysosomes. Autophagy maintains cell homeostasis by recycling degraded cytoplasmic components and damaged organelles.

Development and Validation of a Clinic Machine Learning Classifier for the Prediction of Risk Stratifications of Prostate Cancer Bone Metastasis Progression to Castration Resistance.

Objective: To explore the predictive factors and predictive model construction for the progression of prostate cancer bone metastasis to castration resistance.

Methods: Clinical data of 286 patients diagnosed with prostate cancer with bone metastasis, initially treated with endocrine therapy, and progressing to metastatic castration resistant prostate cancer (mCRPC) were collected. By comparing the differences in various factors between different groups with fast and slow occurrence of castration-resistant prostate cancer (CRPC).

Identifying the oral microbiome of adolescents with and without dental fluorosis based on full-length 16S rRNA gene sequencing.

Dental fluorosis, resulting from long-term environmental exposure to fluoride, is prevalent among diverse populations worldwide. Severe fluorosis not only compromises the aesthetic appeal of teeth but also impairs their functionality. This study aims to investigate the oral microbiome in dental fluorosis and the health individuals of adolescents living in the endemic fluorosis area of Guizhou, China through full-length 16S rDNA sequencing.

Effective TME-related signature to predict prognosis of patients with head and neck squamous cell carcinoma.

The tumor microenvironment (TME) is crucial for the development of head and neck squamous cell carcinoma (HNSCC). However, the correlation of the characteristics of the TME and the prognosis of patients with HNSCC remains less known. In this study, we calculated the immune and stromal cell scores using the "estimate" R package.

Potentially Inappropriate Medication Use Among Older Patients with Diabetes in a Chinese Community.

Background: Potentially inappropriate medications (PIMs) are frequently prescribed to older people with diabetes. This study aimed to assess the prevalence of PIM use in older people with diabetes and identify potential risk factors influencing the development of PIM use.

Methods: This was a cross-sectional study conducted in an outpatient setting in Beijing, China, using Chinese criteria.

Deep hydrocarbon genesis and accumulation model of strike-slip fault reservoirs in the Yuemanxi area of the Tarim Basin.

As a clean and environmentally friendly energy source, deep oil and gas has always been the focus of the oil and gas industry. The study of hydrocarbon accumulation in deep strike-slip fault zones is a challenging and important area of research in the oil and gas industry. In particular, accurately modeling oil and gas accumulation in the Yuemenxi area of the Tarim Basin presents significant difficulties due to the varying physical properties and gas composition of the Ordovician reservoirs, as well as the complex origin of oil and gas in the area.

Immunomodulatory effects of umbilical mesenchymal stem cell-derived exosomes on CD4 T cells in patients with primary Sjögren's syndrome.

Background: Primary Sjögren's syndrome (pSS) is an autoimmune disease that leads to the destruction of exocrine glands and multisystem lesions. Abnormal proliferation, apoptosis, and differentiation of CD4 T cells are key factors in the pathogenesis of pSS. Autophagy is one of the important mechanisms to maintain immune homeostasis and function of CD4 T cells.

A New EBS2b-IBS2b Base Paring (A/T) Improved the Gene-Targeting Efficiency of Thermotargetron in Escherichia coli.

Thermophilic group II intron is one type of retrotransposon composed of intron RNA and intron-encoded protein (IEP), which can be utilized in gene targeting by harnessing their novel ribozyme-based DNA integration mechanism termed "retrohoming." It is mediated by a ribonucleoprotein (RNP) complex that contains the excised intron lariat RNA and an IEP with reverse transcriptase (RT) activity. The RNP recognizes targeting sites by exon-binding sequences 2 (EBS2)/intron-binding sequences 2 (IBS2), EBS1/IBS1, and EBS3/IBS3 bases pairing.

Atorvastatin ameliorated PM-induced atherosclerosis in rats.

PM2.5 provokes atherosclerotic events. Atorvastatin presents anti-inflammatory and antioxidant activities, and may ameliorate PM2.

Prevalence of myopia and associated risk factors among key schools in Xi'an, China.

Background: The aim of this study is to investigate the prevalence of myopia and high myopia and the associated risk factors in key schools in Xi'an, China.

Methods: This cross-sectional study started in September 2021 and was conducted for one month. A total of 11,011 students from 10 key primary schools, five key junior high schools and five key high schools in Xi'an were randomly selected to undergo visual acuity measurement and non-cycloplegic autorefraction.

Fluorinated leaning pillar[6]arene: synthesis, structure and selective iodide anion binding by anion-π interactions.

Anion recognition has continuously attracted significant attention due to its important role in environmental and biological sciences. Here, we have designed and synthesized an electron-deficient fluorinated leaning pillar[6]arene 1 that contains two tetrafluoro-benzene units. The electron-deficient fluorinated leaning pillar[6]arene 1 is capable of selectively recognizing iodide anions to form a host-guest complex with 1 : 1 stoichiometry driven by anion-π interactions.

Genome-wide identification and characterization of the HSP gene superfamily in apple snails (Gastropoda: Ampullariidae) and expression analysis under temperature stress.

Apple snails from the family Ampullariidae have become economically important due to several species mainly from the genus Pomacea being invasive. The heat shock proteins (HSPs), which are important molecular chaperones for species responding to various stresses, have been proved to play critical roles in adapting harsh environments in the invasive apple snails. The recent release of the genomes of Pomacea canaliculata, Pomacea maculata, Lanistes nyassanus, and Marisa cornuarietis has opened the opportunity for a comprehensive analysis of HSP superfamily in the ampullariids.

Metformin and the risk of dementia based on an analysis of 396,332 participants.

Background: AMPK has attracted widespread interest as a potential therapeutic target for age-related diseases, given its key role in controlling energy homeostasis. Metformin (Met) has historically been used to treat Type 2 diabetes and has been shown to counteract age-related diseases. However, studies regarding the relationship between Met and a variety of age-related classifications of cognitive decline have reported mixed findings.

[Characteristics and Dfferences of Dissolved Oxygen Stratification in Different Tributaries of Three Gorges Reservoir During Impoundment Period].

Taking the Xiaojiang and Xiangxi Rivers, two typical tributaries of the Three Gorges Reservoir, as examples, this study analyzed and compared the hydrodynamic, thermal stratification, and temporal and spatial differences in dissolved oxygen (DO) and their responses to the water storage process in the two tributaries through field monitoring at different stages of the 2020 impoundment period. The results showed that:① at the initial stage of water storage, the DO in the surface layer of the Xiaojiang River was higher (7.00-13.

Hybrid Nanostructure Catalyst with Low Loading of Pt for the High-Efficiency Catalytic Hydrogenation of Chloronitrobenzene.

Fabrication of low-loading, noble-metal, stable, and high-performance metal catalysts remains a thorny issue. Herein, we demonstrate the successful formation of a hybrid nanostructure Pt/TiO/SBA-15 catalyst (denoted as HNSC-P/T/S; Pt, 0.09%; TiO, 10%) with satisfactory activity in the hydrogenation of -chloronitrobenzene (-CNB).

Intraoperative Optical Coherence Tomography-guided 25G Microamount Trajectory Vitrectomy for the Treatment of Penetrating Ocular Injury Caused by a Foreign Body in the Right Eye: A Case Study.

Background: Optical coherence tomography (OCT) is a real-time three-dimensional tomography optical imaging technology that uses near-infrared waves to take cross-sectional pictures of the retina and other tissues. A few studies have reported the use of intraoperative OCT navigation for the removal of foreign bodies from the eyeball during surgery. The objective is to present a single case with a small foreign body (not embedded in the retina) treated with intraoperative OCT guided 25G micro-amount trajectory vitrectomy.

Dynamics of - and -Harboring Microbial Communities Across an Age Sequence of Biological Soil Crusts Under Sand-Fixation Plantation.

Biological soil crusts (BSCs) are important for restoring vegetation and improving soil fertility in arid or semiarid desertified land. However, studies on the contribution of BSC microbes to phosphorus (P) transformation remains limited. The microbial diversity involved in P transformation and its dynamic along BSC development should be examined to further understand the microbial regulatory mechanism of the P-cycling process.

Identification of Rat Testicular Leydig Precursor Cells by Single-Cell-RNA-Sequence Analysis.

Stem Leydig cells (SLCs) play a critical role in the development and maintenance of the adult Leydig cell (ALC) population. SLCs also are present in the adult testis. Their identification, characteristics, and regulation in the adult testis remain uncertain.

Integrative Analysis of Peripheral Blood Indices for the Renal Sinus Invasion Prediction of T1 Renal Cell Carcinoma: An Ensemble Study Using Machine Learning-Assisted Decision-Support Models.

Purpose: Renal sinus invasion is an attributive factor affecting the prognosis of renal cell carcinoma (RCC). This study aimed to construct a risk prediction model that could stratify patients with RCC and predict renal sinus invasion with the help of a machine learning (ML) algorithm.

Patients And Methods: We retrospectively recruited 1229 patients diagnosed with T1 stage RCC at the Baotou Cancer Hospital between November 2013 and August 2021.

Detection of Aliphatic Aldehydes by a Pillar[5]arene-based Fluorescent Supramolecular Polymer with Vaporchromic Behavior.

The detection of volatile aliphatic aldehydes is of significance because of their chemical toxicity, physical volatility and widespread applications in chemical industrial processes. In this work, the direct detection of aliphatic aldehydes is tackled using a pillar[5]arene-based fluorescent supramolecular polymer with vaporchromic behavior. Thin films with strong orange-yellow fluorescence are prepared by coating the linear supramolecular polymer on glass sheets.