Publications by authors named "Zhao Wen-Xin"
Article Synopsis
- Thyroid surgery has improved with new techniques like robotic and endoscopic surgery that help patients recover faster but also come with some challenges.
- In a study of 472 surgeries, robotic surgery took longer to learn and had longer operation times, but it did better at removing lymph nodes without harming important nerves.
- Both types of surgery are safe, but robotic surgery might need special training to use effectively; better training programs could help doctors perform these surgeries even better in the future.
Article Synopsis
- The study investigates the role of systemic inflammatory markers (SIMs) in predicting long-term survival for patients undergoing endovascular abdominal aortic aneurysm (EVAR) procedures.
- It involved a retrospective analysis of 147 patients, identifying key markers such as neutrophil-to-lymphocyte ratio (NLR) and hemoglobin-to-red cell distribution width ratio (HRR) that correlate with mortality.
- Findings indicate that higher NLR and lower HRR are linked to significantly higher mortality rates, suggesting these markers may help in patient selection for EVAR procedures.
Significance: Near-infrared autofluorescence (NIRAF) utilizes the natural autofluorescence of parathyroid glands (PGs) to improve their identification during thyroid surgeries, reducing the risk of inadvertent removal and subsequent complications such as hypoparathyroidism. This study evaluates NIRAF's effectiveness in real-world surgical settings, highlighting its potential to enhance surgical outcomes and patient safety.
Aim: We evaluate the effectiveness of NIRAF in detecting PGs during thyroidectomy and central neck dissection and investigate autofluorescence characteristics in both fresh and paraffin-embedded tissues.
Papillary thyroid cancer (PTC) stands as one of the most prevalent types of thyroid cancers, characterized by a propensity for in-situ recurrence and distant metastasis. The high mobility group protein (HMGB1), a conserved nuclear protein, plays a pivotal role in carcinogenesis by stimulating tumor cell growth and migration. Nevertheless, the underlying mechanism driving aberrant HMGB1 expression in PTC necessitates further elucidation.
View Article and Find Full Text PDFObjective: To enhance the accuracy in predicting lymph node metastasis (LNM) preoperatively in patients with papillary thyroid microcarcinoma (PTMC), refining the "low-risk" classification for tailored treatment strategies.
Methods: This study involves the development and validation of a predictive model using a cohort of 1004 patients with PTMC undergoing thyroidectomy along with central neck dissection. The data was divided into a training cohort (n = 702) and a validation cohort (n = 302).
Optimizing robotic thyroid surgery: lessons learned from an retrospective analysis of 104 cases.
Front Endocrinol (Lausanne)
February 2024
Article Synopsis
- Robotic surgery is getting better and helps doctors perform thyroid operations more accurately and safely.
- In a study of 104 patients, doctors found that as they did more robotic surgeries, they got faster and had fewer complications.
- Once doctors did around 37 surgeries, they became really efficient, leading to happy patients and good recovery times.
Article Synopsis
- Scientists created a new AI tool called PTAIR 2.0 to help doctors find the parathyroid glands during thyroid surgery, which is super important to avoid health problems after surgery.
- They trained this AI using thousands of images and videos to make it really smart at recognizing these glands.
- Tests showed that PTAIR 2.0 works better than both new and experienced doctors, which could make surgeries safer and help patients recover faster!
Objective: This study aimed to conduct a meta-analysis evaluating the optimal timing for endovascular repair of acute versus subacute uncomplicated Type B Aortic Dissection.
Method: PubMed, EMBASE, web of science and Cochrane Library was interrogated to identify Electronic bibliographic studies updated to January 2023 to collect studies compared the clinical outcomes of endovascular repair for Acute Versus Subacute Uncomplicated Type B Aortic Dissection. Data were aggregated as pooled odds ratios (OR) using the fixed or random effects models according to the significance of heterogeneity, Pooled odds ratios (OR) were calculated by RevMan 5.
NADPH oxidases 2 (NOX2) is the main source of ROS in macrophages, which plays a critical role in the formation of atherosclerosis. However, effects of NOX2 inhibition on established vulnerable plaques and the potential role involved remain unclear. The purpose of this study is to investigate the latent mechanism of NOX2-triggered vulnerable plaque development.
View Article and Find Full Text PDFArticle Synopsis
- Papillary thyroid cancer (PTC) is a type of thyroid tumor that rarely spreads to the skin but, when it does, leads to poor survival rates.
- A patient with scalp metastasis from PTC showed a significant reduction in tumor sizes after receiving three cycles of anlotinib, a medication usually used for other advanced cancers.
- Anlotinib continued after surgery further decreased tumor size, suggesting it could effectively treat similar cases of cancer metastasis in the future.
Purpose: The present study discussed the effects of accidental parathyroid resection on hypoparathyroidism and investigated the risk factors associated with accidental parathyroid resection.
Methods: Clinical data from patients who have undergone thyroidectomy at a university hospital in the period from November 2018 and October 2020 were entered into the database and analyzed. Risk factors for accidental parathyroid resection were recorded.
Objective: We aimed to establish an artificial intelligence (AI) model to identify parathyroid glands during endoscopic approaches and compare it with senior and junior surgeons' visual estimation.
Methods: A total of 1,700 images of parathyroid glands from 166 endoscopic thyroidectomy videos were labeled. Data from 20 additional full-length videos were used as an independent external cohort.
Introduction: This study aims to evaluate the predictive value of color Doppler ultrasound for the diagnosis of aberrant right subclavian artery (ARSA) with a co-occurring non-recurrent right laryngeal nerve (NRLN).
Material And Methods: In the present study, 58 patients with ARSA (ARSA group) and 1,280 patients without ARSA (controls) were diagnosed by ultrasonography. In addition, 32 patients with ARSA (ARSA operation group) and controls underwent thyroidectomy with surgical exploration with or without NRLN.
Background: Endoscopic thyroidectomy is popular among patients with cosmetic requirements. However, when lateral neck dissection (LND) is required, endoscopic surgery may be challenging. Therefore, we introduced needle-assisted endoscopic technique to achieve endoscopic LND procedure and evaluated its safety and feasibility in the present study.
View Article and Find Full Text PDFNMR-based metabolomics to select a surgical method for treating papillary thyroid carcinoma.
Clinics (Sao Paulo)
November 2018
Objective: This study aims to investigate differences in the metabolomic profiles of patients who received different surgeries for papillary thyroid carcinoma (PTC).
Methods: Two surgical methods, i.e.
Objective: To study the feasibility of gas-liquid mixing tumescent solution for creating a working space (WS) in endoscopic thyroidectomy (ET).
Materials And Methods: A prospective study was performed on 186 patients with thyroid tumor who had undergone ET via chest and breast approach. Patients were randomly divided into 2 groups to receive traditional tumescent solution as group A and modified tumescent solution (gas-liquid mixing tumescent solution) as group B.
Objective: Analysis of the metabolic differences among the papillary thyroid carcinoma (group T) patients, benign thyroid tumor patients (group B) and healthy controls (group H) by nuclear magnetic resonance hydrogen spectrum.
Methods: collect twenty serum specimens each from group T, group B and group H. Collect image archive.
[Characteristics of erectile dysfunction in old males with lacunar infarction].
Zhonghua Nan Ke Xue
September 2006
Objective: To investigate the characteristics of erectile dysfunction (ED) in old males with lacunar infarction.
Methods: A total of 38 old patients ages from 60 to 70 years were involved. The questionnaire of international index of erectile function 5 (IIEF -5) was used to determine the status and severity of ED.