Publications by authors named "Zhao Shuo"

The application of classic foaming agent faces several issues, including excessive use of defoaming agent, inadequate defoaming, pipeline blockage due to silicone oil precipitation, and high development cost of the foaming agent. To address the aforementioned issues, a novel intelligent foaming agent was created. This resulted in the development of a new intelligent foaming and discharging agent system.

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Hsp90, a crucial molecular chaperone, regulates diverse client proteins, impacting both normal biology and disease. Central to its function is its conformational plasticity, driven by ATPase activity and client interactions. However, comprehensive insights into Hsp90's dynamic molecular transitions remain elusive.

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Background: The disease impact of breast cancer is to view the couple as a whole, breast cancer is a disease shared by the couple. Cancer coping has evolved from an individual perspective to a dyadic coping perspective for couples. The purpose of this study was to identify and describe the dyadic coping categories of couples with breast cancer and to analyze the relationship between dyadic coping categories and post-traumatic growth (PTG) in couples with breast cancer.

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Introduction: Establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2), a member of the EFO2 family, is implicated in the pathogenesis and progression of various cancers. However, there has been limited comprehensive pan-cancer analysis conducted on ESCO2 thus far.

Methods: Publicly available databases, such as the UCSC Xena database, were utilized to examine differential expression patterns across various cancer types.

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Solid state photon upconversion by triplet-triplet annihilation (TTA), particularly near-infrared (NIR)-to-blue upconversion, holds instant promise for enhancing optoelectronic and photochemical applications. Despite extensive studies, NIR-to-blue upconversion has remained particularly challenging and elusive due to inherent multiple energy-downhill processes in TTA upconversion. In this study, using atomically thin two dimensional (2D) monolayer semiconductor as a triplet sensitizer, we demonstrate an efficient and robust solid-state NIR-to-blue photon upconversion system.

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  • - The research focuses on identifying the geographical origin of rhubarb using stable isotopes and elemental analysis, collecting 190 samples from 38 locations in China, specifically Gansu, Sichuan, and Qinghai.
  • - Results showed varying carbon and nitrogen content across regions, with notable isotopic differences and correlations with environmental factors like longitude, humidity, and latitude.
  • - Advanced classification models (LDA, PLS-DA, k-NN) demonstrated high accuracy (82.1% to 91.7%) in distinguishing the origins of rhubarb, indicating this method can enhance future studies on rhubarb’s geographical origin and medicinal efficacy.
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  • * A new bacteriophage called pK3-24 was discovered, which specifically targets and can effectively kill ST447 K. pneumoniae, showing potential as an alternative to antibiotics.
  • * Phage pK3-24 has a stable double-stranded DNA genome, does not carry antibiotic resistance genes, and has demonstrated effectiveness in reducing biofilm production and mortality in infected larvae.
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Notably, clear cell renal cell carcinoma (ccRCC) is characterized by a distinct metabolic tumor phenotype that involves the reprogramming of multiple metabolic pathways. Although there is increasing evidence linking FUCA1 to malignancies, its specific role and downstream signaling pathways in ccRCC remain poorly understood. Here we found that FUCA1 expression was significantly downregulated in ccRCC tissues, which also predicts poor prognosis of ccRCCpatients.

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  • - This study investigates the role of neutral red (NR) as an electron mediator during the electrosynthesis of succinic acid by Actinobacillus succinogenes, emphasizing its integration into bacterial cell membranes for efficiency in microbial electrochemical cells (MECs).
  • - Findings show that while NR is quickly absorbed during bacterial growth, adding more NR does not significantly boost acid production, and any loss of membrane-bound NR is not supplemented by NR in the fermentation liquid.
  • - The research highlights the importance of controlling electro-potential to reduce NR degradation, which is crucial for maintaining MEC functionality and efficiency in long-term electrosynthesis processes.
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In recent years, research on attribute-based encryption (ABE) has expanded into the quantum domain. Because a traditional single authority can cause the potential single point of failure, an improved lattice-based quantum-resistant identity authentication and policy attribute encryption scheme is proposed, in which the generation of random values is optimized by adjusting parameters in the Gaussian sampling algorithm to improve overall performance. Additionally, in the key generation phase, attributes are processed according to their shared nature, which reduces the computational overhead of the authorization authority.

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Taste sensation recognition is a core for taste-related queries. Most prior research has been devoted to recognizing the basic taste sensations using the Brain-Computer Interface (BCI), which includes EEG, MEG, EMG, and fMRI. This research aims to recognize electronic taste (E-Taste) sensations based on surface electromyography (sEMG).

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Objective: It is important to discriminate different headaches in clinical practice, and neurocognitive biomarkers may serve as objective tools. Several reports have suggested potential cognitive impairment for primary headaches, whereas cognitions within specific domains remain elusive, e.g.

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  • A study analyzed respiratory specimens from 128 children with pneumonia in Beijing, revealing that 77.3% tested positive for a specific pathogen, particularly affecting younger patients.
  • The most common strains were identified through gene typing, showing a notable increase in macrolide-resistant mutations, especially in children under three years old.
  • Severe pneumonia was observed in 56.2% of analyzed cases, with longer fever durations and higher complication rates, highlighting the necessity for clinicians to recognize the severity linked to macrolide-resistant infections.
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Endovascular treatment (EVT) using stents has become the primary option for severe cerebrovascular stenosis. However, considerable challenges remain to be addressed, such as in-stent restenosis (ISR) and late thrombosis. Many modified stents have been developed to inhibit the hyperproliferation of vascular smooth muscle cells (SMCs) and protect vascular endothelial cells (VECs), thereby reducing such complications.

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  • Recent advances in light-sheet microscopy now allow for 3D analysis of microvascular networks in brain tissue without the need for histological sectioning, which was previously a barrier.
  • In a study involving mice after a stroke model, researchers observed significant changes in microvessels over time, including an initial loss followed by a reemergence and increased complexity of small microvessels within 56 days.
  • The administration of FTY720 (Fingolimod) after ischemia enhanced the growth and branching of small microvessels, highlighting its potential in improving microvascular architecture following a stroke.
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Ammonia (NH) in exhaled breath (EB) has been a biomarker for kidney function, and accurate measurement of NH is essential for early screening of kidney disease. In this work, we report an optical sensor that combines ultraviolet differential optical absorption spectroscopy (UV-DOAS) and spectral reconstruction fitting neural network (SRFNN) for detecting NH in EB. UV-DOAS is introduced to eliminate interference from slow change absorption in the EB spectrum while spectral reconstruction fitting is proposed for the first time to map the original spectra onto the sine function spectra by the principle of least absolute deviations.

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The delay in wound healing caused by chronic wounds or pathological scars is a pressing issue in clinical practice, imposing significant economic and psychological burdens on patients. In particular, with the aging of the population and the increasing incidence of diseases such as diabetes, impaired wound healing is one of the growing health problems. MicroRNA (miRNA) plays a crucial role in wound healing and regulates various biological processes.

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  • - The study investigates how joint attention affects communication, particularly looking at social impairments in people with schizotypal traits using a Posner cueing paradigm focused on gaze and head orientation cues.
  • - Key findings indicate that people with schizotypal traits have abnormal attentional responses to invalid gaze cues, showing increased theta brainwave activity linked to these traits.
  • - The research suggests that theta frequency activity plays a crucial role in the relationship between schizotypal traits and joint attention, providing insights for future interventions aimed at improving social interactions.
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  • This study investigates how absolute neutrophil count (ANC) and absolute monocyte count (AMC) can help distinguish between renal cell carcinoma (RCC) and renal angiomyolipoma (RAML) and their implications on RCC patient prognosis.
  • The research analyzed data from 1120 patients, finding significantly higher ANC and AMC levels in RCC patients compared to those with RAML, and noted associations with factors like smoking history and tumor characteristics.
  • Additionally, high ANC and AMC levels were linked to poorer overall survival (OS) and progression-free survival (PFS) in RCC patients, with ANC being identified as a potential independent prognostic factor.
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  • - The study investigated how various strains of bacteria associated with nonalcoholic fatty liver disease enter a viable but nonculturable (VBNC) state to survive harsh environments.
  • - It was found that high-alcohol-producing strains entered the VBNC state more slowly than medium and low-alcohol strains, with high salt concentration and low oxygen accelerating loss of culturability.
  • - The research developed new methods for analyzing and quantifying these VBNC states, revealing potential risks for public health since VBNC bacteria cannot be detected using standard culture techniques.
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Molecular chaperone heat shock protein 90 (Hsp90) is a ubiquitous regulator that fine-tunes and remodels diverse client proteins, exerting profound effects on normal biology and diseases. Unraveling the mechanistic details of Hsp90's function requires atomic-level insights into its client interactions throughout the adenosine triphosphate-coupled functional cycle. However, the structural details of the initial encounter complex in the chaperone cycle, wherein Hsp90 adopts an open conformation while engaging with the client, remain elusive.

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Silkworm was the first domesticated insect and has important economic value. It has also become an ideal model organism with applications in genetic and expression studies. In recent years, the use of transgenic strategies has made the silkworm silk gland an attractive bioreactor for the production of recombinant proteins, in particular, -mediated transgenes.

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Sulfur compounds (SO, CS, HS and OCS) are common toxic pollutants in the atmospheric environment, and the absorption spectroscopy technique can indeed help to realize online monitoring of their concentrations. However, nonlinear effects that occur during absorption spectroscopy measurements have a serious impact on the measurement of the absorption cross-sections (ACSs) of sulfur compounds, leading to serious deviations in both the substance absorption properties and concentrations obtained based on ACS analysis. In this paper, the maximum effective ACSs of sulfur compounds in the linear region are obtained by considering the influence of nonlinear effects and eliminating interference factors such as oxygen and photolysis.

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() was first discovered in Japan in 2009 and has since spread worldwide. It exhibits strong transmission ability, high multidrug resistance, blood infectivity, and mortality rates. Traditional diagnostic techniques for have shortcomings, leading to difficulty in its timely diagnosis and identification.

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