A hierarchical Bilayered scaffold for periodontal complex structure regeneration.

The periodontal tissue comprises alveolar bone, cementum, and periodontal ligament (PDL), forming a highly hierarchical architecture. Although current therapies could regenerate the hard tissue well, the simultaneous reconstruction of hard and soft tissue remains a great clinical challenge with the major difficulty in highly orientated PDL regeneration. Using the unidirectional freeze-casting method and biomimetic mineralization technique, we construct a hierarchical bilayer scaffold with the aligned chitosan scaffold with ZIF-8 resembling PDL, and intrafibrillarly mineralized collagen resembling alveolar bone.

Interlayer donor-acceptor pair excitons in MoSe/WSe moiré heterobilayer.

Localized interlayer excitons (LIXs) in two-dimensional moiré superlattices exhibit sharp and dense emission peaks, making them promising as highly tunable single-photon sources. However, the fundamental nature of these LIXs is still elusive. Here, we show the donor-acceptor pair (DAP) mechanism as one of the origins of these excitonic peaks.

Construction and external validation of a nomogram model for predicting the risk of esophageal stricture after endoscopic submucosal dissection: a multicenter case-control study.

Esophageal stricture is a common complication after endoscopic submucosal dissection (ESD) for superficial esophageal cancer and precancerous lesions, we intend to investigate the independent risk factors of esophageal stricture after ESD by adding the data of included living habits, established a nomogram model to predict the risk of esophageal stricture, and verified it by external data. The clinical data and living habits of patients with early esophageal cancer and precancerous lesions who underwent ESD in the Affiliated Hospital of North Sichuan Medical College and Langzhong People's Hospital from March 2017 to August 2021 were retrospectively collected. The data collected from the two hospitals were used as the development group (n = 256) and the validation group (n = 105), respectively.

Organic-inorganic covalent-ionic molecules for elastic ceramic plastic.

Although organic-inorganic hybrid materials have played indispensable roles as mechanical, optical, electronic and biomedical materials, isolated organic-inorganic hybrid molecules (at present limited to covalent compounds) are seldom used to prepare hybrid materials, owing to the distinct behaviours of organic covalent bonds and inorganic ionic bonds in molecular construction. Here we integrate typical covalent and ionic bonds within one molecule to create an organic-inorganic hybrid molecule, which can be used for bottom-up syntheses of hybrid materials. A combination of the organic covalent thioctic acid (TA) and the inorganic ionic calcium carbonate oligomer (CCO) through an acid-base reaction provides a TA-CCO hybrid molecule with the representative molecular formula TACa(CaCO).

Experimental Investigation of Cobalt Deposition on 304 Stainless Steel in Borated and Lithiated High-Temperature Water.

The radioactive corrosion products Co and Co in the primary loops of pressurized water reactors (PWRs) are the main sources of radiation doses to which workers in nuclear power plants are exposed. To understand cobalt deposition on 304 stainless steel (304SS), which is the main structural material used in the primary loop, the microstructural characteristics and chemical composition of a 304SS surface layer immersed for 240 h in borated and lithiated high-temperature water containing cobalt were investigated with scanning electron microscopy (SEM), X-ray diffraction (XRD), laser Raman spectroscopy (LRS), X-ray photoelectron spectroscopy (XPS), glow discharge optical emission spectrometry (GD-OES), and inductively coupled plasma emission mass spectrometry (ICP-MS). The results showed that two distinct cobalt deposition layers (an outer layer of CoFeO and an inner layer of CoCrO) were formed on the 304SS after 240 h of immersion.

Variation of Aroma Components of Pasteurized Yogurt with Different Process Combination before and after Aging by DHS/GC-O-MS.

Pasteurized yogurt is a healthy yogurt that can be stored in ambient temperature conditions. Dynamic headspace sampling (DHS) combined with gas chromatography-olfactory mass spectrometry (GC-O-MS), sensory evaluation, electronic nose (E-nose), and partial least squares discriminant analysis (PLS-DA) were used to analyze the flavor changes of pasteurized yogurt with different process combinations before and after aging. The results of odor profiles showed that the sensory descriptors of fermented, sweet, and sour were greatly affected by different process combinations.

Telecom single-photon emitters in GaN operating at room temperature: embedment into bullseye antennas.

The ideal single-photon source displaying high brightness and purity, emission on-demand, mature integration, practical communication wavelength (i.e., in the telecom range), and operating at room temperature does not exist yet.

A sensitive fluorescence detection strategy for HO and glucose by using aminated Fe-Ni bimetallic MOF as fluorescent nanozyme.

An aminated Fe-Ni bimetallic metal-organic framework (FeNi-MOF-NH) with both peroxidase-like activity and fluorescence properties was developed. FeNi-MOF-NH possessed the enhanced peroxidase-like activity through the enhanced electron transfer process and hydroxyl radical (·OH) generation. It was found that the amino group endowed the material with fluorescent property and the metal site Ni in FeNi-MOF-NH could also enhance the fluorescence emission intensity (Ex = 345 nm, Em = 452 nm).

Artificial intelligence-aided preparation of perovskite SrFeZrO catalysts for ozonation degradation of organic pollutant concentrated water after membrane treatment.

Membrane technology has been widely used to treat wastewater from a variety of industries, but it also results in a large amount of concentrated wastewater containing organic pollutants after membrane treatment, which is challenging to decompose. Here in this work, a series of perovskite SrFeZrO catalysts were prepared via a modified co-precipitation method and evaluated for catalytic ozone oxidative degradation of m-cresol. An artificial neural intelligence networks (ANN) model was employed to train the experimental data to optimize the preparation parameters of catalysts, with SrFeZrO being the optimal catalysts.

Strain Quantum Sensing with Spin Defects in Hexagonal Boron Nitride.

Hexagonal boron nitride is not only a promising functional material for the development of two-dimensional optoelectronic devices but also a good candidate for quantum sensing thanks to the presence of quantum emitters in the form of atom-like defects. Their exploitation in quantum technologies necessitates understanding their coherence properties as well as their sensitivity to external stimuli. In this work, we probe the strain configuration of boron vacancy centers (VB) created by ion implantation in h-BN flakes thanks to wide-field spatially resolved optically detected magnetic resonance and submicro Raman spectroscopy.

Label-free fluorescence detection of hydrogen peroxide and glucose based on the Ni-MOF nanozyme-induced self-ligand emission.

A bifunctional Ni-MOF nanosheet was synthesized and developed for label-free fluorescent detection of HO and glucose. The Ni-MOF exhibited intrinsic peroxidase-like activity and its catalytic activity was demonstrated to be originated from the hydroxyl radicals (•OH) produced in catalytic process. Since the generated •OH enabled terephthalic acid, the non-fluorescent organic ligand of Ni-MOF, to form a strongly fluorescent 2-hydroxy terephthalic acid, the Ni-MOF nanozyme was endowed with dual-function properties of mimicking peroxidase and emitting fluorescence.

Characterization of key aroma-active compounds in Hanyuan Zanthoxylum bungeanum by GC-O-MS and switchable GC × GC-O-MS.

The present study sought to characterize the composition of volatile aroma compounds and key aroma-active compounds of dried Hanyuan Zanthoxylum bungeanum. The volatile aroma compounds were analyzed by the solid-phase microextraction (SPME) combined with gas chromatography-olfactometry-mass spectrometry (GC-O-MS) and two-dimensional comprehensive gas chromatography-olfactometry-mass spectrometry (GC × GC-O-MS). The key aroma-active compounds were analyzed by the aroma extract dilution analysis and odor activity value.

An efficient multi-enzyme cascade platform based on mesoporous metal-organic frameworks for the detection of organophosphorus and glucose.

An efficient colorimetric detection platform based on multi-enzyme cascade has been developed for detection of organophosphorus. Firstly, the dual-enzyme platform was prepared and applied for sensitive glucose detection (detection limit 0.32 μM).

Synergetic PtNP@CoO hollow nanopolyhedrals as peroxidase-like nanozymes for the dual-channel homogeneous biosensing of prostate-specific antigen.

In this paper, novel synergetic PtNP@CoO hollow nanopolyhedrals with peroxidase-like activities are designed and prepared, which can be used as electrochemical and colorimetric signal labels for the enzyme-free dual-channel homogeneous sensing of prostate-specific antigen. When prostate-specific antigens are present, the aptamer-modified PtNP@CoO hollow nanopolyhedrals and magnetic beads form sandwich structures, which have excellent peroxidase-like activities, because of the synergetic effect of PtNP@CoO hollow nanopolyhedrals. The sandwich structures can be separated from the mixture by the magnetic effect of the magnetic beads and catalyze the redox reactions between HO and TMB, generating quantitative electrochemical and colorimetric responses in homogeneous solution simultaneously.