Publications by authors named "Zhao Haibo"

Invasive surgical methods are the current standard for hemostasis and wound closure. In recent years, injectable hydrogels prepared from natural biomacromolecules have shown promise as tissue adhesives to overcome their shortcomings due to their high hydrophilicity and biocompatibility, but the inherent properties of unmodified biomolecules remain a major challenge in their application. In this paper, a hydrogel (DS/Gel-CDH) with self-healing, injectable and adhesive functions was constructed by Schiff base crosslinking between carbonyl hydrazide modified gelatin (Gel-CDH) and dialdehyde starch (DS).

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We treated the burst spinal fracture with posterior subtotal corpectomy and reconstruction. In some cases, the endplate and the adjacent disc can be preserved during the operation. The adjacent disc retained its mobility after the removal of the posterior pedicle screws.

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Tendons are fibrous connective tissues that transmit force from muscles to bones. Despite their ability to withstand various loads, tendons are susceptible to significant damage. The healing process of tendons and ligaments connected to bone surfaces after injury presents a clinical challenge due to the intricate structure, composition, cellular populations, and mechanics of the interface.

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Bio-based aerogels, which are poised as compelling thermal insulators, demand intricate synthesis procedures and have limited durability under harsh conditions. The integration of smart stimuli-response transitions in biomass aerogels holds promise as a solution, yet remains a challenge. Here, we introduce a pioneering strategy that employs reversible-gel-assisted ambient-pressure drying without organic solvents to craft multifunctional bio-based aerogels.

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Article Synopsis
  • Gastric cancer is a significant health issue worldwide, and this study explores the impact of fatty acid metabolism on the disease to improve clinical decisions by analyzing gene subtypes through public databases and machine learning.
  • The researchers identified 71 differentially expressed genes (DEGs) related to fatty acid metabolism, creating two gene subtypes (C1 and C2) and found notable differences in immune responses between them.
  • A prognostic model was developed based on these gene subtypes, allowing for classification of patients into high-risk and low-risk groups; this model can aid clinicians in evaluating patient prognosis and making informed treatment decisions.
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Short-chain fatty acids (SCFAs), which are saturated fatty acids consisting of six or fewer carbon atoms, have been found to be closely associated with the biological behavior of malignant tumors. This manuscript provides a comprehensive review on the role of SCFAs in regulating cell cycle, apoptosis, tumor angiogenesis, epithelial-mesenchymal transition, protein regulatory pathways, and histone regulation in promoting the development of malignant tumors. Furthermore, we discuss the potential therapeutic strategies targeting SCFAs for treating malignant tumors.

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Developing green and efficient delivery systems to promote bioavailability of bioactive ingredients is a sustained demand in food industry. In this work, the astaxanthin (AST)-loaded starch-based fast-dissolving nanofibers with core-shell structure were prepared by emulsion electrospinning technique without using any organic solvent. To load water-insoluble AST in hydrophilic octenyl succinic anhydride starch (OSAS)/polyvinyl alcohol (PVA) nanofiber matrices, AST-loaded nanoscale emulsions (212.

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Anterior cruciate ligament (ACL) injury is a common orthopedic disease with a high incidence, long recovery time, and often requiring surgical treatment. However, the susceptibility factors for ACL injury are currently unclear, and there is a lack of analysis on the differences in the ligament itself. Previous studies have focused on germline mutations, with less research on somatic mutations.

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To address the current development requirements for multifunctional cotton fabrics, a phytic acid-induced flame-retardant hydrophobic coating containing nitrogen (N), phosphorus (P), and silicon (Si) was grafted on the surface of cotton fabrics using a facile step-by-step immersion method. The limiting oxygen index value improved to 31.2 %, decreasing to 26.

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Cotton fabrics with the main constituent of cellulose, which is hydrophilic, bacterial infected, and flammable, are in urgent need of functionalization as a kind of widely applied material. To address these issues, in this work, modified polyelectrolyte complex (MPEC) coatings with polyethylenimine (PEI), polyphosphate (APP), and perfluorodecyltrichlorosilane modified PEI (PFTS-PEI) are prepared to construct multi-functionally gradient MPEC coatings on cotton fabrics. Stability and synergistic effects on hydrophobicity, antibacterial activity, and flame retardancy in this system have been studied.

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As an alternative to traditional dietary fibers with prebiotic effects, the interaction between resistant starch III (RS3) and gut microbiota is worth exploring. In this study, the effects of RS3 on the proliferation of Bifidobacterium adolescentis (B. adolescentis) and their structural changes before and after fermentation were investigated.

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Approved anticancer drugs typically face challenges due to their narrow therapeutic window, primarily because of high systemic toxicity and limited selectivity for tumors. Prodrugs are initially inactive drug molecules designed to undergo specific chemical modifications. These modifications render the drugs inactive until they encounter specific conditions or biomarkers , at which point they are converted into active drug molecules.

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Aims: The purpose of this study was to find out the relation between visceral adipose index (VAI) levels and stress urinary incontinence (SUI) in adult women.

Methods: From the National Health and Nutrition Examination Survey (NHANES) 2007-2020, females aged 20 or above were identified for this study. Visceral adiposity was determined using the VAI score, and the assessment of urinary incontinence was carried out through a correlation questionnaire.

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In this study, starch-based nanofiber mats were successfully prepared from aqueous solution by electrospinning and used for probiotic encapsulation for the first time. The physicochemical properties of the octenylsuccinated (OS) starch/poly(vinyl alcohol) (PVA) blend solutions were systematically investigated. Through Fourier transform infrared spectroscopy and X-ray diffraction spectra analysis, it was found that miscibility and hydrogen bonding interactions exist between OS starch and PVA molecules.

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Article Synopsis
  • Flexible polyurethane foam (FPUF) is widely used in furniture and technical applications but struggles with flame retardancy and durability in harsh conditions.
  • A new solution involves adding a specially designed chemical, DTAP, that enhances FPUF's properties by creating strong bonds and capturing free radicals.
  • With just 5.1 wt% of DTAP, the modified foam passed burn tests and showed significant improvements in strength and durability, even after extended exposure to heat.
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Passive radiant cooling is a potentially sustainable thermal management strategy amid escalating global climate change. However, petrochemical-derived cooling materials often face efficiency challenges owing to the absorption of sunlight. We present an intrinsic photoluminescent biomass aerogel, which has a visible light reflectance exceeding 100%, that yields a large cooling effect.

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Curdlan, a natural polysaccharide, exhibits emulsion-stabilizing and viscosity-modifying properties. However, when employed solely in the aqueous phase, curdlan's adhesive nature impedes droplet dispersion, resulting in a gel-like structure with limited applicability. This investigation formulated a biphasic stabilized oil-in-water emulsion by supplementing the oil phase with beeswax and the aqueous phase with curdlan and soy protein isolate (SPI).

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Atmospheric drying method for fabricating aerogels is considered the most promising way for casting aerogels on a large scale. However, the organic solvent exchange, remaining environmental pollution risk, is a crucial step in mitigating the impact of surface tension during the atmospheric drying process, especially for wet gel formed through the alkoxy-derived sol-gel process, such as melamine-formaldehyde resin (MF) aerogel. Herein, a tough polymer-assisted in situ polymerization was proposed to fabricate MF resin aerogel with a combination of mechanical toughness and strength, enabling it to withstand the capillary force during water evaporation.

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Polyurethane (PU) foams, pivotal in modern life, face challenges suh as fire hazards and environmental waste burdens. The current reliance of PU on potentially ecotoxic halogen-/phosphorus-based flame retardants impedes large-scale material recycling. Here, our demonstrated controllable catalytic cracking strategy, using cesium salts, enables self-evolving recycling of flame-retardant PU.

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Here, a novel multifunctional coating containing bio-based phytic acid (PA), L-glutamic acid (L-Glu), and trimesoyl chloride (TMC) is constructed by a simple soaking strategy, giving cotton fabrics excellent flame retardancy, washability, and antibacterial properties. The coating layer on the cotton surface was prepared via the electrostatic and hydrogen bonding between PA and L-Glu, accompanied by the interface polymerization between PA, L-Glu, and TMC. Among them, the limiting oxygen index value of the treated cotton fabrics (C and C-TMC) was as high as 40 %.

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Breast cancer (BC) is the most prominent form of cancer among females all over the world. The current methods of BC detection include X-ray mammography, ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography and breast thermographic techniques. More recently, machine learning (ML) tools have been increasingly employed in diagnostic medicine for its high efficiency in detection and intervention.

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Spike length (SL) is one of the most important agronomic traits affecting yield potential and stability in wheat. In this study, a major stable quantitative trait locus (QTL) for SL, i.e.

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Introduction: Epithelial Ovarian cancer most commonly presents at advanced stages with extra-abdominal disease metastasis. Notably, enlarged cardiophrenic lymph nodes are found in 10.5-62 % of patients with advanced ovarian cancer.

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The hydrophilic and low mechanical properties limited the application of starch-based films. In this work, a hydrophobic starch-based nanofiber mat was first successfully prepared from aqueous solution at room temperature by using electrospinning and glutaraldehyde (GTA) vapor phase crosslinking techniques for active packaging applications. Catechin (CAT) was immobilized in the nanofibers by electrospinning, resulting in higher thermal stability (T = 315.

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