Efficacy of active ingredients in Qingdai on ulcerative colitis: a network pharmacology-based evaluation.

Objective: To elucidate the protective effect of Qingdai (, QD) on ulcerative colitis (UC) by means of and approaches.

Methods: A systems pharmacology analysis was per-formed to predict the active components of QD whereas the putative biological targets of QD against UC were obtained through target fishing, network cons-truction and enrichment analyses. Meanwhile, we examined the ameliorative effect of QD in a mouse model of dextran sulfate sodium (DSS)-induced colitis.

Network pharmacology dissection of multiscale mechanisms for jiaoqi powder in treating ulcerative colitis.

Ethnopharmacological Relevance: The incidence of ulcerative colitis (UC) is increasing worldwide, making it a serious public health challenge. Currently, there are no accepted curative treatments for UC. As such, the exploration of new therapeutic strategies for UC treatment is of considerable clinical importance.