Publications by authors named "Zhanzhan Dai"
Article Synopsis
- Trauma can lead to dangerous complications like severe infections and coagulopathies, exacerbated by the release of cell-free nucleic acids (cfNAs) from damaged cells.
- Researchers are exploring cationic hyperbranched polyaminoglycosides, particularly HPT and ss-HPT, which have shown effectiveness in scavenging cfNAs and reducing inflammation and hypercoagulation following trauma.
- In mouse models, ss-HPT displayed superior accumulation in injured tissues and enhanced biodegradation in healthy tissues, suggesting it could improve therapeutic outcomes for trauma patients by targeting post-injury inflammation and coagulation issues.
Background: Hypertrophic scars are one of the main complications that affect the quality of life of patients after burns. Many methods have been shown to be effective in the treatment of hypertrophic scars, such as ablative fractional CO laser (AFCL) and platelet-rich plasma (PRP). However, there are few studies on the effect of the combined application of these measures.
View Article and Find Full Text PDFBackground: The Reelin (RELN) gene encodes the protein reelin, which is a large extracellular matrix glycoprotein that plays a key role in brain development. Additionally, this protein may be involved in memory formation, neurotransmission, and synaptic plasticity, which have been shown to be disrupted in schizophrenia (SCZ). A decreasing trend in the expression of RELN mRNA in the brain and peripheral blood of SCZ patients has been observed.
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