Publications by authors named "Zhanli Peng"
Article Synopsis
- Lower limb arterial occlusive disease is often treated with paclitaxel-coated balloons (PCBs), but post-treatment restenosis (re-narrowing) remains a major issue.
- The study found that the NLRP3 protein is activated during this process, promoting blood vessel cell proliferation, migration, and resistance to the effects of paclitaxel.
- Using a compound called JQ1 alongside paclitaxel showed promising results in preventing restenosis, suggesting a potential new treatment strategy for patients.
Background: Ruptured atherosclerotic plaques often precipitate severe ischemic events, such as stroke and myocardial infarction. Unraveling the intricate molecular mechanisms governing vascular smooth muscle cell (VSMC) behavior in plaque stabilization remains a formidable challenge.
Methods: In this study, we leveraged single-cell and transcriptomic datasets from atherosclerotic plaques retrieved from the gene expression omnibus (GEO) database.
Article Synopsis
- Atherosclerosis (AS) is a serious condition characterized by plaque buildup in blood vessels, which can lead to severe health issues like strokes and heart attacks; necroptosis, a specific type of cell death, might play a role in this process, but its involvement in AS hasn't been thoroughly studied yet.
- Researchers utilized gene expression data from the GEO database to find genes linked to necroptosis in AS, ultimately identifying a set of differentially expressed genes (NRDEGs) that could serve as diagnostic markers and help in understanding the progression and prognosis of the disease.
- Among these genes, TRAF5 was highlighted as a significant diagnostic marker for AS, and various experimental techniques were employed to analyze its role and the
Recently, many sparse-based direction-of-arrival (DOA) estimation methods for coprime arrays have become popular for their excellent detection performance. However, these methods often suffer from grid mismatch problem due to the discretization of the potential angle space, which will cause DOA estimation performance degradation when the target is off-grid. To this end, we proposed a sparse-based off-grid DOA estimation method for coprime arrays in this paper, which includes two parts: coarse estimation process and fine estimation process.
View Article and Find Full Text PDFNested arrays are considered attractive due to their hole-free performance, and have the ability to resolve O ( N 2 ) sources with O ( N ) physical sensors. Inspired by nested arrays, two kinds of three-parallel nested subarrays (TPNAs), which are composed of three parallel sparse linear subarrays with different inter-element spacings, are proposed for two-dimensional (2-D) direction-of-arrival (DOA) estimation in this paper. We construct two cross-correlation matrices and combine them as one augmented matrix in the first step.
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