Publications by authors named "Zhanhao Wang"
Article Synopsis
- - Antimony (Sb) migration in soil and water is mainly controlled by how well it sticks to ferrihydrite (FH), and this process is affected by natural organic matter like humic acid (HA).
- - The study shows that factors such as pH and concentration significantly impact the adsorption of Sb(V), with lower pH reducing adsorption and longer contact time improving it; FH has a better capacity to adsorb Sb(V) compared to FH-HA complexes.
- - Findings from X-ray photoelectron spectroscopy indicate that Sb(V) attaches primarily through ligand exchange, with HA helping to keep Sb(V) in place, making FH-HA complexes a viable option for long-term Sb retention in environmental cleanup efforts.
Hypobaric hypoxia (HH) characteristics induce impaired cognitive function, reduced concentration, and memory. In recent years, an increasing number of people have migrated to high-altitude areas for work and study. Headache, sleep disturbance, and cognitive impairment from HH, severely challenges the physical and mental health and affects their quality of life and work efficiency.
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- * A literature review covering 40 years identified 71 medicinal species and 18 Chinese compound prescriptions that mainly exhibit antioxidant and anti-inflammatory effects to combat MI/R injury.
- * The findings highlight the pharmacological mechanisms of TCMs, providing a foundation for future research and development of TCM-based treatments for MI/R injury.
Dysregulation of alternative splicing of hTERT gene to generate full-length Htert (hTERT-FL) that reactivate telomerase has been recognized as a major pathological alteration in pancreatic cancer (PrCa). Mechanism about the factors that regulate hTERT-FL splicing is lacking. Through bioinformatics approach, we focus on a candidate splicing factor RBM10, which leads to a switch in hTERT transcripts to generate a function-less isoform hTERT-s in PrCa, suppressed both telomerase activity and subsequent telomere shortening.
View Article and Find Full Text PDF[The morphological changes of SW620 cells induced by over-expression of human sorting nexin 3].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
August 2015
Objective: To explore the effect of human sorting nexin 3 (hSNX3) on the morphology and migration of colorectal cancer cells through over-expression of hSNX3 in SW620 cells.
Methods: A lentiviral vector pEZ-Lv201 (pEZ-SV40-eGFP-IRES-Puro) inserted with hSNX3 gene was transferred into SW620 cells to construct and package recombinant lentiviral expression vector pEZ-hSNX3-Lv201. The cell clones stably over-expressing hSNX3 (SW620hSNX3) were screened to observe cell morphology and migration ability using Transwell(TM) assay and wound scratch assay.