380 MPa-30% grade biodegradable Zn-Mn-Mg-Ca alloy: Bimodal grain structure, large work-hardening strain, and enhanced biocompatibility.

Strain softening is a common issue for high-strength biodegradable Zn alloys. We developed Zn-0.6Mn-0.

Study on the Enhanced Degradable Rate of the Zn-0.4Li Alloys as Biodegradable Implants by Anodization.

Biodegradable Zn-0.4Li alloys have been considered as medical implants due to their excellent mechanical properties and desirable biocompatibility. In this work, anodization was applied to modified corrosion resistance of the Zn-0.

Highly plastic Zn-0.3Ca alloy for guided bone regeneration membrane: Breaking the trade-off between antibacterial ability and biocompatibility.

A common problem for Zn alloys is the trade-off between antibacterial ability and biocompatibility. This paper proposes a strategy to solve this problem by increasing release ratio of Ca ions, which is realized by significant refinement of CaZn particles through bottom circulating water-cooled casting (BCWC) and rolling. Compared with conventionally fabricated Zn-0.

How surface-to-volume ratio affects degradation of magnesium: and studies.

Despite the many studies carried out over the past decade to determine the biodegradation performance of magnesium and its alloys, few studies focused on the effect of altered surface area to volume ratio on and degradation rate and osteogenesis. Here, high purity magnesium cylindrical rods with gradient of surface area to volume ratio were processed by excavating different numbers of grooves on the side surface. The immersion test in SBF solution and the rat femoral condylar bone defect model were used to evaluate the degradation of magnesium rods and , respectively.

Nanomechanical probing of bacterial adhesion to biodegradable Zn alloys.

Bacterial infections on implants cause an inflammatory response and even implant failure. Bacterial adhesion is an initial and critical step during implant infection. The prevention of bacterial adhesion to implant materials has attracted much attention, especially for biodegradable metals.

Surface-Roughness-Induced Plasticity in a Biodegradable Zn Alloy.

Improving plasticity has been an eternal theme of developing metallic materials. It is difficult to increase room-temperature elongation of metallic materials over 100% without sacrificing strength using existing methods. Herein, surface-roughness-induced plasticity (SRIP) is discovered in biodegradable Zn-0.

Development of a high-strength Zn-Mn-Mg alloy for ligament reconstruction fixation.

Although various biodegradable materials have been investigated for ligament reconstruction fixation in the past decades, only few of them possess a combination of high mechanical properties, appropriate degradation rate, good biocompatibility, and osteogenic effect, thus limiting their clinical applications. A high-strength Zn-0.8Mn-0.

Insight into role and mechanism of Li on the key aspects of biodegradable ZnLi alloys: Microstructure evolution, mechanical properties, corrosion behavior and cytotoxicity.

ZnLi based alloys have been proved as desirable candidates for biodegradable materials accounting for its high mechanical performance and great biocompatibility. However, effects of Li on microstructure and comprehensive properties of Zn alloys are seldom investigated and need to be addressed. Herein, Zn-(0.

Enhancement in mechanical and corrosion resistance properties of a biodegradable Zn-Fe alloy through second phase refinement.

Biodegradable Zn alloys containing Fe suffer from a common problem that FeZn second phase particles are coarse. This problem roots thermodynamically from the negligible solid solubility of Fe in Zn and priority of FeZn solidification over Zn. In this paper, bottom circulating water-cooled casting method is successfully developed to significantly refine FeZn particles in Zn-0.

Design biodegradable Zn alloys: Second phases and their significant influences on alloy properties.

Alloying combined with plastic deformation processing is widely used to improve mechanical properties of pure Zn. As-cast Zn and its alloys are brittle. Beside plastic deformation processing, no effective method has yet been found to eliminate the brittleness and even endow room temperature super-ductility.

Research on elastic recoil and restoration of vessel pulsatility of Zn-Cu biodegradable coronary stents.

Coronary stents made of zinc (Zn)-0.8 copper (Cu) (in wt%) alloy were developed as biodegradable metal stents (Zn-Cu stents) in this study. The mechanical properties of the Zn-Cu stents and the possible gain effects were characterized by in vitro and in vivo experiments compared with 316L stainless steel stents (316L stents).

Hemocompatibility of biodegradable Zn-0.8 wt% (Cu, Mn, Li) alloys.

Zinc alloys have been explored as potential materials for biodegradable vascular stents due to their tolerable corrosion rates and tunable mechanical properties. However, the performances of Zn alloys were not supported with enough toxicity or biological compatibility evaluation, particularly hemocompatibility for vascular scaffolding application. In this work, the hemocompatibility of three zinc alloys (Zn-0.

Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery.

In the present study, a novel biodegradable Zn-0.8Cu coronary artery stent was fabricated and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed that the implanted stent was able to maintain structural integrity after 6 months, while its disintegration occurred after 9 months of implantation.

Effects of Ag, Cu or Ca addition on microstructure and comprehensive properties of biodegradable Zn-0.8Mn alloy.

Zn-0.8Mn (in wt%) alloy with good ductility is used for design of novel Zn-0.8Mn-0.