Publications by authors named "Zhangtao Zhang"
Article Synopsis
- PEDF is a secreted glycoprotein with various biological functions, including neuroprotection and anti-cancer effects, particularly in cancers like prostate, ovarian, and pancreatic.
- The study investigated the role of PEDF in colorectal cancer by measuring its expression in human cancer tissues and evaluating the effects of recombinant PEDF on cancer cell behavior.
- Findings showed that PEDF levels were lower in colorectal cancer tissues, and treatment with recombinant PEDF reduced cancer cell migration and invasion while enhancing cell adhesion, suggesting that increasing PEDF levels could be a potential therapeutic strategy to prevent colorectal cancer metastasis.
