Investigation of the osteogenic effects of ICA and ICSII on rat bone marrow mesenchymal stem cells.

Icariin (ICA) serves as the primary biologically active compound in traditional Chinese medicine Epimedium, while Icariside II (ICSII) represents one of its gastrointestinal metabolites. Although ICA and ICSII have demonstrated osteogenic differentiation- promoting effects on BMSCs, there is limited literature comparing their effects and underlying mechanisms. This study aimed to compare the osteogenic effects of Icariin and Icariside II, along with their respective osteogenic mechanisms.

Two-stage extraction by partial grinding of impacted mandibular third molar in close proximity to the inferior alveolar nerve.

Background: Extraction of impacted third molars often leads to severe complications caused by damage to the inferior alveolar nerve (IAN).

Aim: To proposes a method for the partial grinding of an impacted mandibular third molar (IMM3) near the IAN to prevent IAN injury during IMM3 extraction.

Methods: Between January 1996 and March 2022, 25 patients with IMM3 roots near the IAN were enrolled.

Effect of core and veneer porcelain thickness and resin cement on opalescence property of glass-ceramic veneers.

Objectives: This study aimed to analyze the effect of core and veneer porcelain thickness and resin cement on the opalescence property (OP) of glass-ceramic veneers, which were used to restore discolored teeth.

Methods: IPS e.max CAD LT A3 ceramic specimens were fabricated by computer aided design and computer aided manufacturing (CAD/CAM).