Synopsis of recent research by authors named "Zhangmei Chang"
- Zhangmei Chang's research primarily focuses on the interactions between enterovirus 71 (EV71), a virus responsible for hand, foot, and mouth disease, and the host immune system, particularly the roles of STAT3 in viral infection and pathogenesis.
- The development of a rapid method to rescue infectious EV71 using cDNA clones and cells expressing T7 polymerase has been a key innovation, enabling quicker responses to viral outbreaks.
- Recent findings suggest that EV71 not only antagonizes the antiviral activity of host STAT3 but also influences cytokine production, indicating a complex relationship between the virus and host immune responses.
