A seroepidemiological investigation of Lyme disease in Qiongzhong County, Hainan Province in 2019-2020.

Background: The incidence and prevalence of Lyme disease are expanding and rising, respectively, which constitutes a worldwide public health problem. The present study aimed to investigate the prevalence of Lyme disease (LD) in Qiongzhong County, Hainan, and to determine the LD infection level in the local population, so as to provide evidence for further local LD surveillance as well as effective prevention and treatment measures.

Methods: A total of 252 serum samples were collected from cases with suspected LD in Qiongzhong County, including 159 and 93 cases with joint and neurological symptoms, respectively.

Report of Two Novel Thalassemia Variants, : c.181delG and : c.121_126delAAGACC, in Chinese Individuals.

In this study, we report two novel thalassemia variants detected in Chinese individuals using targeted NGS technology. We detected a novel frameshift variant, : c.181delG, in a 32-year-old Chinese individual.