Synopsis of recent research by authors named "Zhangke Li"
- Zhangke Li's recent research focuses on the role of extracellular vesicles in the development of drug resistance in glioblastoma, particularly in response to the chemotherapy drug temozolomide (TMZ).
- His 2022 study demonstrates that miR-27a-3p carried by extracellular vesicles promotes TMZ resistance by targeting the BTG2 gene, suggesting a novel mechanism of therapeutic resistance in glioblastoma.
- The findings highlight the importance of extracellular vesicles as mediators of communication in tumor biology and their potential as therapeutic targets to improve treatment outcomes for glioblastoma patients.
