Publications by authors named "Zhangjie Li"

Background: The recovery of upper limb function is of great significance for stroke patients to regain their self-care ability, yet it is still a difficult point in clinical practice of neurological rehabilitation. This study aimed to investigate the effect of Maitland joint mobilization technique on the recovery of upper extremity function in patients with spasticity after stroke.

Methods: From August to December 2023, 71 patients with upper extremity flexor spasm after stroke were recruited and randomly divided into experimental group (n = 35) and control group (n = 36).

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Drug-induced cardiotoxicity is a significant contributor to drug recalls, primarily attributed to limitations in existing drug screening platforms. Traditional heart-on-a-chip platforms often employ metallic electrodes to record cardiomyocyte electrical signals. However, this approach hinders direct cardiomyocyte morphology observation and typically yields limited functionality.

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Background: Families of patients with hematologic neoplasms involved in dignity therapy have exhibited a remarkable improvement in psychological well-being and family functioning. However, the applicability and generalizability of family participatory dignity therapy are limited as it is influenced by factors such as intervention time, place, and participants. Whether remote support from significant others is feasible and effective remains unknown.

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Targeted microrobotic delivery within the circulatory system holds significant potential for medical theranostic applications. Existing delivery strategies of microrobots encounter challenges such as slow speed, limited navigation control, and dispersal under dynamic flow conditions. Furthermore, within the realm of microrobots, testing platforms often lack essential biological microenvironments, while studies conducted on animal models are constrained by limited detection resolution.

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organoid models, typically defined as 3D multicellular aggregates, have been extensively used as a promising tool in drug screening, disease progression research, and precision medicine. Combined with advanced microfluidics technique, organoid-on-a-chip can flexibly replicate organs within the biomimetic physiological microenvironment by accurately regulating different parameters, such as fluid conditions and concentration gradients of biochemical factors. Since engineered organ reconstruction has opened a new paradigm in biomedicine, innovative approaches are increasingly required in micro-nano fabrication, tissue construction, and development of pharmaceutical products.

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Objective: To explore the current status and interaction of perceived stress, job burnout and mental health among healthcare workers after the opening of COVID-19 which occurred in December 2022.

Methods: A cross-sectional study of 792 healthcare workers from three tertiary hospitals in Wuxi was conducted from January 2023 to February 2023. Sociodemographic questionnaire, Perceived Stress Scale, Burnout Scale and Mental Health Self-Assessment Questionnaire were used for investigation.

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Thermal homeostasis is vital for mammals and is controlled by brain neurocircuits. Yet, the neural pathways responsible for cold defense regulation are still unclear. Here, we found that a pathway from the lateral parabrachial nucleus (LPB) to the dorsomedial hypothalamus (DMH), which runs parallel to the canonical LPB to preoptic area (POA) pathway, is also crucial for cold defense.

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Purpose: This study aimed to understand and identify barriers to resilience in young and middle-aged patients with lymphoma in the context of Chinese culture.

Methods: A qualitative descriptive study was employed. Face-to-face, semi-structured, and in-depth individual interviews were conducted between May and July 2022.

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Objectives: To investigate the relationship between burn-out, emotional labour and psychological resilience of gastroenterology nurses during the COVID-19 pandemic and explore the factors associated with these specific variables.

Design: A multicentre cross-sectional study with anonymous self-reporting was conducted from 24 November 2021 to 26 December 2021.

Setting: The study was conducted in Fujian Province, China.

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In this paper, we prepared a series of CeTiO (x = 0-0.20) nanorods by hydrothermal method, which were used to construct the PdCu/CeTiO catalysts. The CeTiO and PdCu/CeTiO samples were characterized by transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), N adsorption-desorption, X-ray diffraction (XRD), inductively coupled plasma optical emission spectrometer (ICP-OES), etc.

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Hypothesis: MXenes (two-dimensional early transition metal carbides and carbonitrides) possess both excellent conductivity and surface hydrophilicity, enabling more diverse potential applications. However, in flexible strain sensors, the flexible substrates are usually composed of hydrophobic elastomers such as thermoplastic polyurethane (TPU). To enhance the interactions between MXenes and hydrophobic.

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Article Synopsis
  • Spinal cord injury (SCI) leads to serious motor and sensory deficits, highlighting the urgent need for effective treatment options, such as the use of menstrual blood-derived mesenchymal stem cells (MenSCs).
  • In a study, MenSCs were transplanted into rats with incomplete thoracic spinal cord injuries, resulting in improved hind limb motor function, reduced cavity formation, and increased mature neuron presence compared to untreated rats.
  • The study found that MenSCs enhance recovery through increased brain-derived neurotrophic factor (BDNF) levels and reduced inflammation, suggesting that MenSCs could be a promising new therapy for SCI patients.
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