Publications by authors named "Zhanggui Ding"

A gram-stain-positive, aerobic, rod-shaped bacterial strain capable of producing siderophores, named YIM B08730, was isolated from a soil sample collected from Wumeng Mountain National Nature Reserve, Zhaotong City, Yunnan Province. Growth occurred at 10-45 °C (optimum, 35-40 ℃), pH 7.0-9.

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Article Synopsis
  • * Teadenol B significantly inhibits the growth of all four breast cancer cell subtypes, particularly showing a strong effect on MDA-MB-231 cells, known for their poor clinical outcomes, by reducing deoxycytidine triphosphate deaminase (DCTD), important for DNA synthesis and repair.
  • * The compound also promotes autophagy by increasing the conversion of LC3-I to LC3-II, suggesting a mechanism behind its anti-cancer effects and indicating potential for teadenol B as both a preventive
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In this study, a novel aerobic mesophilic bacterial strain with capable of degrading chitin, designated YIM B06366, was isolated and classified. The rod-shaped, Gram-stain-negative, on-spore-forming bacterium originated from rhizosphere soil sample collected in Kunming City, Yunnan Province, southwest PR China. Strain YIM B06366 exhibited growth at temperatures between 20 and 35 °C (optimum, 30 °C) and at pH 6.

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A new Gram-negative, rod-shaped, flagellated bacterium was isolated from soil in the Guishan, Xinping County, Yuxi City, Yunnan Province, China, and named YIM B01952. Growth occurred at 10-40 °C (optimum, 30 °C), pH 6.0-9.

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A novel Gram-staining negative, aerobic, rod-shaped bacterium, designated strain YIM DDC1, was isolated from an estuary sediment sample of Dongda River flowing into Dianchi lake in Yunnan, southwest China. The strain displayed growth at 10-40 °C (optimum of 28 °C), pH 5.0-9.

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A new aerobic bacterial strain, designated strain YIM B02290, was isolated from the soil of Machangqing, Dali city, Yunnan Province, China. Cells were Gram-stain-positive, sporogenous, rod-shaped, and motile with peritrichous flagella. Strain YIM B02290 showed the highest 16S rRNA gene sequence similarity with Brevibacillus laterosporus (97.

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A Gram-stain-negative, aerobic, rod-shaped bacteria strain, named YIM B01951, was isolated from a forest soil sample collected from Mopan Mountain National Forest Park, Xinping City, Yunnan Province, southwest PR China (101°58'06" N, 23°03'02" E). Growth occurred at 15-40 °C (optimum, 30 °C), pH 5.0-8.

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Huagaimu (Manglietiastrum sinicum) trees are critically endangered species and classified as a plant species with extremely small populations in China. Rhizospheres and bulk soils prokaryotic communities play an important role to protect and promote plants health and growth. However, the compositions and structures of prokaryotic communities in wild and reintroduced M.

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A novel halophilic actinobacterial strain, designated YIM 96934, was isolated from a soil sample collected from the edge of a saline lake in Xinjiang, north-west China. The taxonomic position of the strain was investigated using a polyphasic approach. Cells of the strain were aerobic and Gram-stain-positive.

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A new pregnane steroid, named aspergillon A (), together with two known compounds, (22,24)-ergosta-5,7,22-trien-3-ol () and (22, 24)-ergosta-4,6,8(14),22-tetraen-3-one () were isolated from cultures of the tin mine tailings-associated fungus . The new structure and absolute configuration were determined with the help of extensive spectroscopic analyses and quantum chemical calculations of the electronic circular dichroism (ECD) spectra.

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A new cyclohexenone, named phomaligol D (1), together with two known compounds, kojic acid (2) and phomaligol A (3) were isolated from the tin mine tailings-derived fungus Aspergillus flavus YIM DT 10012. Their structures were elucidated by detailed analysis of spectroscopic data.

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A new phenylspirodrimane dimer, named stachartarin A (1), was isolated from cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Its structures were elucidated by means of spectroscopic methods. At the same time, the compound was tested for its cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells.

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Stachartone A (1), a novel phenylspirodrimane dimer, was isolated from cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Its structure was elucidated by means of spectroscopic methods. At the same time, compound (1) was tested for its cytotoxicity against five human cancer cell lines.

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A Gram-positive, non-motile, asporogenous and aerobic bacterium, designated YIM 98012, was isolated from a salt lake in China. Strain YIM 98012 was found to be catalase and oxidase positive. Optimal growth of strain YIM 98012 was observed at 37 °C and pH 7.

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A novel aerobic, Gram-positive, non-motile halotolerant actinobacterium, designated strain YIM 96448, was isolated from a saline soil sample collected from the south bank of Aiding Lake in Xinjiang Province, northwest China. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain YIM 96448 is closely related to Phytoactinopolyspora endophytica EGI 60009 (98.0%) and Phytoactinopolyspora alkaliphila EGI 80629 (97.

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Two new diketopiperazines, named diphenylalazine C (1) and epicoccin U (2), together with six known compounds (3-8) were isolated from the EtOAc extract of the fermentation broth of the tin mine tailings-derived fungus Schizophyllum commune YIM DT 10058. Their structures were elucidated by detailed analysis of spectroscopic data and comparison with related known compounds. Compounds 1 and 2 exhibited weak antibacterial and cytotoxic activities.

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Three new drimane sesquiterpenoids, 12-hydroxyalbrassitriol (1), drim-8(12)-en-6β,7α, 9α,11-tetraol (2), and drim-68(12)-dien-9α,11-diol (3), along with one known analog albrassitriol (4), were isolated from cultures of the tin mine tailings-associated fungus Penicillium sp. The new structures were determined on the basis of extensive spectroscopic analyses. All compounds were tested for their cytotoxicities against five human cancer cell lines.

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Unlabelled: Copper sulfate (CuSO4) has been widely used as an algicide to control harmful cyanobacterial blooms (CyanoHABs) in freshwater lakes. However, there are increasing concerns about this application, due mainly to the general toxicity of CuSO4 to other aquatic species and its long-term persistence in the environment. This study reported the isolation and characterization of two natural algicidal compounds, i.

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Objective: Siderophore is a low molecular iron chelate produced by microorganisms. It has broad application prospects in medicine, environmental restoration, health food and other fields. According to the literature survey so far, no siderophore was found from alkaline environment eukaryotes.

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A novel haloalkalitolerant, rod-shaped bacterium, designated strain YIM 4-4, was isolated from the surface water of the Dugerno lake, a haloalkaline lake in Inner Mongolia. The taxonomy of strain YIM 4-4 was investigated by a polyphasic approach. Strain YIM 4-4 was Gram-stain-negative, strictly aerobic, non-motile and formed red colonies.

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A facultatively anaerobic, Gram-staining-negative, pale red-pigmented, non-motile, rod-shaped, moderately halophilic bacterium, designated strain YIM J14(T), was isolated from a sediment sample from a salt mine in Yunnan, south-western China. Growth occurred at NaCl concentrations of between 2 % and 15 % (w/v) and optimally with 5-9 % NaCl. The optimum temperature and pH for growth of the strain were 28 °C and pH 7.

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Griseusins F (1) and G (2), two 2a-hydro-8a-(2-oxopropyl)-substituted spiro-naphthoquinones with a previously undescribed C23 polyketide skeleton, were isolated from a Yunnan tin mine tailings-derived alkalophilic actinomycete, Nocardiopsis sp. YIM DT266. Their complete structure assignments with the absolute stereochemistry were elucidated by spectroscopic data, X-ray crystal diffraction, calculation of optical rotation, and CD spectroscopic analysis.

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Streptomyces auratus strain AGR0001 produces neophoslactomycin A, a novel analog of phoslactomycin that possesses potent activity against some phytopathogenic fungi. Here, the draft genome sequence of S. auratus strain AGR0001 is presented, which would provide insight into the biosynthetic mechanism of neophoslactomycin A.

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Phenazinolins A-E (1-5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1-3 and the oxabicyclo[3.

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