High Impedance Microstrip Resonators and Transceiver Arrays for Ultrahigh Field 10.5T MR Imaging.

Multichannel transceiver coil arrays are needed to enable parallel imaging and B1 manipulation in ultrahigh field MR imaging and spectroscopy. However, the design of such transceiver coils and coil arrays often faces technical challenges in achieving the required high operating frequency at the ultrahigh fields and sufficient electromagnetic (EM) decoupling between resonant elements. In this work, we propose a high impedance microstrip transmission line resonator (HIMTL) technique that has unique high frequency capability and adequate EM decoupling without the use of dedicated decoupling circuits.

Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.

Physical exercise is a cornerstone for preventing diet-induced obesity, while it is unclear whether physical exercise could offset high-fat, high-calories diet (HFCD)-induced cardiac dysfunction. Here, mice were fed with HFCD and simultaneously subjected to physical exercise. As expected, physical exercise prevented HFCD-induced whole-body fat deposition.

High glucose induces renal tubular epithelial cell senescence by inhibiting autophagic flux.

Autophagy, a cellular degradation process involving the formation and clearance of autophagosomes, is mediated by autophagic proteins, such as microtubule-associated protein 1 light chain 3 (LC3) and sequestosome 1 (p62), and modulated by 3-methyladenine (3-MA) as well as chloroquine (CQ). Senescence, characterised by permanent cell cycle arrest, is marked by proteins such as cyclin-dependent kinase inhibitor 1 (p21) and tumour protein 53 (p53). This study aims to investigate the relationship between cell senescence and renal function in diabetic kidney disease (DKD) and the effect of autophagy on high-glucose-induced cell senescence.

Characteristics and prognostic values of abdominal aortic branches calcification in hemodialysis patients.

Background: Vascular calcification is highly prevalent and associated with mortality in hemodialysis patients. However, extreme splanchnic arterial calcification in calciphylaxis with poor prognosis raises questions regarding the reliability of previous vascular calcification scoring methods. Therefore, this study aimed to examine the distribution characteristics of abdominal aortic branch calcification and identify a more reliable predictor of mortality in hemodialysis patients.

Development and Validation of a Nomogram-Based Model to Predict Primary Hypertension Within the Next Year in Children and Adolescents: Retrospective Cohort Study.

Background: Primary hypertension (PH) poses significant risks to children and adolescents. Few prediction models for the risk of PH in children and adolescents currently exist, posing a challenge for doctors in making informed clinical decisions.

Objective: This study aimed to investigate the incidence and risk factors of PH in Chinese children and adolescents.

Electride transition in liquid aluminum under high pressure and high temperature.

Despite the conventional view of liquid aluminum (l-Al) as a simple metal governed by the free-electron model, it exhibits unique bonding characteristics. This study uncovers a gradual transition from free electron to electride behavior in l-Al at high pressure and temperature, forming a type of two-component liquid where atomic and electride states coexist. The proportion of electride increases with pressure and temperature until reaching saturation, leading to notable changes in the pair-correlation function and coordination number of l-Al at saturation pressure.

Effects of GaN substrates of different polarity on the thermal and electronic properties of monolayer MoS.

Monolayer MoS, a compound in two-dimensional TMDs, exhibits excellent physical and chemical properties due to its sandwich structure, making it widely used in the design of nanodevices. We investigated the impact of GaN substrates on the thermal and electronic properties of monolayer MoS. The results reveal that the polarity of the GaN substrate significantly affects the thermal conductivity of monolayer MoS.

High glucose promotes macrophage switching to the M1 phenotype via the downregulation of STAT-3 mediated autophagy.

Aim: Imbalanced M1/M2 macrophage phenotype activation is a key point in diabetic kidney disease (DKD). Macrophages mainly exhibit the M1 phenotype, which contributes to inflammation and fibrosis in DKD. Studies have indicated that autophagy plays an important role in M1/M2 activation.

Microscale quantitation of heavy metals by back-scattering interferometry in conjunction with photothermal effect using a single laser beam.

A microanalytical technique based on the photothermal effect in conjunction with back-scattering interferometry (BSI) using a single laser beam was developed for quantitative detection of heavy metals. After the chromogenic reaction of an analyte in a capillary tube, the photothermal effect induced by irradiation with the same laser beam leads to a change of the refractive index of the solution, which can be "quantified" using the BSI technique. For prove-of-concept, Cu(II) was chosen as the trial analyte, for which the solution changes to purplish through reacting with the chromogenic reagent; a single laser beam of 532 nm was adapted for both inducing the photothermal effect and realizing BSI detection.

A multimodal axial array resonator and its application in radiofrequency (RF) volume coil designs for low-field open magnetic resonance imaging (MRI).

Background: Low-field open magnetic resonance imaging (MRI) systems, typically operating at magnetic field strengths below 1 Tesla, has greatly expanded the accessibility of MRI technology to meet a wide range of patient needs. However, the inherent challenges of low-field MRI, such as limited signal-to-noise ratios and limited availability of dedicated radiofrequency (RF) coils, have prompted the need for innovative coil designs that can improve imaging quality and diagnostic capabilities. In this work, we introduce a multimodal axial array resonator and its implementation in a volume coil, or referred to as a coupled stack-up volume coil, to address these challenges in low-field open MRI.

Coexisting nutcracker phenomenon and refractory hypertension in a patient with IgA nephropathy: A case report and literature review.

The entrapment of the left renal vein (LRV) may contribute to changes in hemodynamics within kidney and could also be associated with IgA nephropathy (IgAN). Although the relationship between the nutcracker phenomenon and IgAN has not yet been elucidated, it is speculated that this patient's refractory hypertension is a combined effect of nutcracker syndrome (NCS) and IgAN.

Opportunities and challenges of foodborne polyphenols applied to anti-aging health foods.

Abstract: With the increasing proportion of the global aging population, aging mechanisms and anti-aging strategies become hot topics. Nonetheless, the safety of non-natural anti-aging active molecule and the changes in physiological function that occur during aging have not been clarified. There is therefore a need to develop safer pharmaceutical interventions for anti-aging.

Tolvaptan and the role of kidney aquaporin-2 abundance in managing volume overload in patients with CKD.

Objective: This retrospective study evaluated tolvaptan's efficacy, safety, and predictive indicators in managing volume overload in chronic kidney disease (CKD) patients.

Methods: CKD patients with volume overload, treated with loop diuretics alone or with tolvaptan at Zhongda Hospital, Southeast University, from 1 March 2022 to 31 December 2023, were included. Patients were divided into loop diuretic (Group C) and loop diuretic combined with tolvaptan (Group T) cohorts.

Surface Matrix-Mediated Cation Exchange of Perovskite Quantum Dots for Efficient Solar Cells.

Cesium-formamidinium lead triiodide perovskite quantum dot (CsFAPbI PQD) is very promising for photovoltaic applications due to its good phase stability and outstanding optoelectronic properties. However, achieving the CsFAPbI PQDs with tunable compositions and robust surface matrix remains a challenge. Here, the surface matrix-mediated cation exchange of PQDs is proposed, in which a bi-functional molecule, tetrafluoroborate methylammonium (FABF), is applied for the cation exchange and stabilizing surface matrix of PQDs.

Study on the Recombinant Human Interferon α1b, α2b, and Gamma Transient Expression and Activities in Tobacco.

Interferons (IFNs) are universally acknowledged for their pivotal role in antiviral and anticancer responses. Thus, the primary aim of our study was to explore the expressions of IFN-α1b, α2b, and gamma in tobacco leaves via agrobacterium-mediated transient transformation and investigate their possible activities. Briefly, fusion with green fluorescent protein tags aided in detecting the expressed IFN proteins in the foliar tissues.

Coupled stack-up volume RF coils for low-field open MR imaging.

Background: Low-field open magnetic resonance imaging (MRI) systems, typically operating at magnetic field strengths below 1 Tesla, has greatly expanded the accessibility of MRI technology to meet a wide range of patient needs. However, the inherent challenges of low-field MRI, such as limited signal-to-noise ratios and limited availability of dedicated radiofrequency (RF) coils, have prompted the need for innovative coil designs that can improve imaging quality and diagnostic capabilities.

Purpose: In response to these challenges, we introduce the coupled stack-up volume coil, a novel RF coil design that addresses the shortcomings of conventional birdcage in the context of low-field open MRI.

Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction.

Background: Cardiac iron overload and ferroptosis greatly contribute to the poor prognosis of myocardial infarction (MI). Iron chelator is one of the most promising strategies for scavenging excessive iron and alleviating cardiac dysfunction post MI. However, various side effects of existing chemical iron chelators restrict their clinical application, which calls for a more viable and safer approach to protect against iron injury in ischemic hearts.

In Situ Formation of Iodide Precursor for Perovskite Quantum Dots with Application in Efficient Solar Cells.

Perovskite quantum dots (PQDs) become a kind of competitive material for fabricating high-performance solar cells due to their solution processability and outstanding optoelectronic properties. However, the current synthesis method of PQDs is mostly based on the binary-precursor method, which results in a large deviation of the I/Pb input ratio in the reaction system from the stoichiometric ratio of PQDs. Herein, a ternary-precursor method with an iodide source self-filling ability is reported for the synthesis of the CsPbI PQDs with high optoelectronic properties.

Correction: First-principles calculations of interfacial thermal transport properties between SiC/Si substrates and compounds of boron with selected group V elements.

Correction for 'First-principles calculations of interfacial thermal transport properties between SiC/Si substrates and compounds of boron with selected group V elements' by Zhehao Sun , 2019, , 6011-6020, https://doi.org/10.1039/C8CP07516F.