Recovery of valuable metals from spent hydrodesulfurization (HDS) catalysts: A comprehensive research review and specific industrial cases.

Spent hydrodesulfurization (HDS) catalysts, produced in the petroleum refining process, are usually classified in hazardous solid waste. Recovery of valuable metals from spent HDS catalyst not only reduce substantially environmental risk but is an important way to alleviate global resource shortages for high-valuable metals. This study reviews numerous references regarding to recovery valuable metals from spent HDS catalyst in last decades, and divided current methods into three processes: pretreatment, oxidation-leaching, and separation-purification processes.

DockEM: an enhanced method for atomic-scale protein-ligand docking refinement leveraging low-to-medium resolution cryo-EM density maps.

Protein-ligand docking plays a pivotal role in virtual drug screening, and recent advancements in cryo-electron microscopy (cryo-EM) technology have significantly accelerated the progress of structure-based drug discovery. However, the majority of cryo-EM density maps are of medium to low resolution (3-10 Å), which presents challenges in effectively integrating cryo-EM data into molecular docking workflows. In this study, we present an updated protein-ligand docking method, DockEM, which leverages local cryo-EM density maps and physical energy refinement to precisely dock ligands into specific protein binding sites.

Generation of transient totipotent blastomere-like stem cells by short-term high-dose Pladienolide B treatment.

As an alternative model for studying the dynamic process of early mammalian embryonic development, much progress has been made in using mouse embryonic stem cells (mESCs) to generate embryo-like structures, especially by modifying the starting cells. A previous study has demonstrated that totipotent blastomere-like cells (TBLCs) can be obtained by continuous treatment of mESCs with a low-dose splicing inhibitor, Pladienolide B (PlaB). However, these totipotent mESCs have limited proliferative capacity.

Midpalatal suture osteotomy combined with microimplant-assisted rapid palatal expansion for adult maxillary transverse deficiency treatment: a study protocol of a randomised controlled trial.

Introduction: Maxillary transverse deficiency (MTD) is a common type of malocclusion. For adult MTD patients with highly ossified midpalatal sutures, surgically assisted rapid palatal expansion (SARPE) has been the conventional method of maxillary expansion. However, SARPE has the disadvantages of significant trauma, high cost and a high incidence of adverse events.

Contrast-Enhanced CT-Based Radiomics Nomogram for Prediction of Pathologic T3a Upstaging in Clinical T1 RCC.

: To develop a nomogram for the preoperative prediction of pathologic T3a (pT3a) upstaging in patients with clinical T1(cT1) renal cell carcinoma (RCC). : A total of 169 cT1 patients with RCC with preoperative contrast-enhanced CT (CECT) and clinical data were enrolled in this study. Afterwards, the sample was split randomly into training and testing sets in a 7:3 ratio.

Application of a novel form of structural classification of the pterygopalatine suture for predicting midpalatal suture expansion by miniscrew-assisted rapid palatal expansion in adults: A cohort study.

Introduction: This study proposes a novel structural parameter, the insertion depth of the pyramidal process into the pterygoid notch (IDP), as a measure of pterygopalatine suture (PPS) resistance during palatal expansion and aims to evaluate the correlation between the IDP-based PPS classification and midpalatal suture (MPS) expansion.

Methods: Preexpansion and postexpansion cone-beam computed tomography images of 23 adults treated with miniscrew-assisted rapid palatal expansion were superimposed. After superimposition, the IDP, sagittal position of the expander, bone thickness penetrated by the miniscrews, PPS separation status (PPS), and MPS expansion at the anterior and posterior nasal spines (hemi-AME and hemi-PME) were determined.

Myelodysplastic syndromes with del(20q) transformed into B-lineage acute lymphoblastic leukemia remaining with del(20q): a case report with literature review.

Background: The transformation of myelodysplastic syndromes (MDS) into acute myeloid leukemia (AML) is common, while it is extremely rarely for acute lymphoblastic leukemia (ALL) transformation. Herein, we described the clinical and cytogenetic features of a case of MDS with del(20q) transformed into B-lineage ALL (B-ALL) remaining with del(20q).

Case Presentation: A 66-year-old Chinese man who presented with pancytopenia, bone marrow hypercellularity and obvious megakaryocytes dysplasia were admitted for treatment.

Design of CoQ crops based on evolutionary history.

Coenzyme Q (CoQ) is essential for energy production by mitochondrial respiration, and it is a supplement most often used to promote cardiovascular health. Humans make CoQ, but cereals and some vegetable/fruit crops synthesize CoQ with a side chain of nine isoprene units. Engineering CoQ production in crops would benefit human health, but this is hindered by the fact that the specific residues of the enzyme Coq1 that control chain length are unknown.

Visible Light-Induced C-H Alkylation of Azauracils with -Hydroxyphthalimide Esters via Catalytic EDA Complex.

Herein, we report sodium iodide (NaI)-catalyzed decarboxylative C-H alkylation of azauracils with -hydroxyphthalimide (NHPI) esters facilitated by visible light activation of catalytic electron donor-acceptor (EDA) complexes. Control experiments and density functional theory calculations suggest that the decarboxylative coupling reaction proceeds via a transiently assembled EDA complex between the NHPI ester and NaI in ,-dimethylacetamide solvent. This synthetic method efficiently applies to primary, secondary, and tertiary NHPI esters under mild, photocatalyst-free, and redox-neutral conditions, achieving high yields of the desired alkylated azauracils.

Optoelectric coordinated modulation of resistive switching behavior in perovskite based synaptic device.

Triple cation halide perovskite (TCP) stands out as a superior photoelectric material, with a broader absorption range, higher absorption efficiency, and improved environmental stability. Due to its excellent synaptic plasticity, TCP facilitates advanced neural morphological operations like light-assisted learning. Here, a modifying layer of polythiophene (P3HT) was incorporated onto the TCP thin film to enhance the resistive switching (RS) characteristics of the synaptic device, which exhibits excellent stability (10 endurance cycles and > 10 s retention time) and low energy consumption (~ 6.

Better Transcriptomic Stability and Broader Transcriptomic Thermal Response Range Drive the Greater Thermal Tolerance in a Global Invasive Turtle Relative to Native Turtle.

Greater thermal tolerance of invasive species benefits their survival and spread under extreme climate events, especially under global warming. Revealing the mechanisms underlying the interspecific differences in thermal tolerance between invasive and native species can help understand the invasion process and predict potential invaders. Here, we link the changes in global transcriptomics and antioxidant defense at multiple temperatures with the differences in thermal limits in the juveniles of a successful globally invasive turtle, Trachemys scripta elegans, and a native turtle in China, Mauremys reevesii.

One-step high-efficiency recovery of high-purity MoO from spent hydrodesulfurization catalyst by water-vapor enhanced sublimation process.

Spent hydrodesulfurization (HDS) catalysts were considered as a vital secondary resource for precious metals like Mo. The current pyrometallurgy and hydrometallurgy usually exhibits the characteristic of remarkable high energy consumption and high secondary pollutions. This study proposes an innovative technique to recycling MoO from spent HDS catalyst by sublimation process at high temperature, which has notable advantages of zero wastewater-generation and zero chemical reagent consumption.

Genetic Diversity and Population Structure of Populations in the Saline-Alkaline Regions of China.

The oriental river prawn is of great economic importance in China. However, its culture in the saline-alkaline regions is limited. This study used D-loop region sequences to analyze the genetic diversity and population structure across the saline-alkaline regions of China.

Protease activity of NIa-Pro determines systemic pathogenicity of clover yellow vein virus.

Clover yellow vein virus (ClYVV), a potyvirus that infects various dicotyledonous plants, poses a significant threat to the cultivation of legumes. Although potyviral NIa-Pro was extensively studied in viral infection cycle and host antiviral responses, the contribution of NIa-Pro protease activity to virus systemic symptoms has not yet been reported. In this study, we developed infectious clones of a ClYVV isolated from Pisum sativum.

Public attitude and media governance of biometric information dissemination in the era of digital intelligence.

Absrtact: In the era of digital intelligence, biometrics plays a critical role in mediating sensitive information dissemination, human-computer interaction, and governance in both virtual and real-world settings, including the evolving metaverse. Based on an empirical analysis of 1,862 participants, the current study investigated factors influencing public perception, acceptance, and risk awareness of biometric technologies. The findings highlight the critical roles of perceived trust (PT) and technical prudence (TP) in driving behavioral intentions (BI), with their positive effects outweighing the significant deterrent impact of perceived risks (PR).

The efficacy of a reporting and data system for computed tomography imaging in assessing the likelihood of malignancy in submandibular salivary gland tumors: a preliminary study.

Objective: To establish a submandibular gland imaging reporting and data system (SI-RADS) and explore its value in diagnosing submandibular gland (SMG) tumors.

Study Design: Patients with primary SMG tumors who underwent enhanced computed tomography (CT) scanning and surgical intervention at Peking University Hospital of Stomatology (2013-2022) were retrospectively included. The imaging data were assessed for acquisition of the relevant imaging features, including lesion boundary, shape, enhancement, calcification, lymph node, and adjacent tissue involvement, and vascular invasion.

Controlled Inflammation Drives Neutrophil-Mediated Precision Drug Delivery in Heterogeneous Tumors.

Tumor heterogeneity remains a formidable obstacle in targeted cancer therapy, often leading to suboptimal treatment outcomes. This study presents an innovative approach that harnesses controlled inflammation to guide neutrophil-mediated drug delivery, effectively overcoming the limitations imposed by tumor heterogeneity. By inducing localized inflammation within tumors using lipopolysaccharide, it significantly amplify the recruitment of drug-laden neutrophils to tumor sites, irrespective of specific tumor markers.

Engineered bio-functional material-based nerve guide conduits for optic nerve regeneration: a view from the cellular perspective, challenges and the future outlook.

Nerve injuries can be tantamount to severe impairment, standard treatment such as the use of autograft or surgery comes with complications and confers a shortened relief. The mechanism relevant to the regeneration of the optic nerve seems yet to be fully uncovered. The prevailing rate of vision loss as a result of direct or indirect insult on the optic nerve is alarming.

Regulation Roles of Juvenile Hormone Epoxide Hydrolase Gene 2 in the Female River Prawn Reproductive Process.

In this study, we investigated the regulatory roles of the () gene in the reproductive process of female . Its total cDNA length was 1848 bp, encoding for 460 amino acids. It contained conserved domains typical of epoxide hydrolases, such as the Abhydrolase family domain, the EHN epoxide hydrolase superfamily domain, and the "WWG" and "HGWP" motifs.

A novel system for classification for midpalatal suture ossification based on pseudocolored and multilayer reconstructed coronal slices: Indication for selection of maxillary expansion methods.

Introduction: A novel method was established for the staging of midpalatal suture (MPS) ossification based on a pseudocoloring stack of anterior and posterior MPS coronal slices obtained by cone-beam computed tomography (CBCT).

Methods: CBCT scans of 240 subjects aged 5-35 years were pseudocolor processed. The slice thickness of stacked anterior and posterior coronal observation planes was set at 5.

Enlarged Perivascular Spaces (EPVS) Associated with Functional and Cognitive Outcome After Aneurysm Subarachnoid Hemorrhage (aSAH).

Aneurysmal rupture is the main cause of subarachnoid hemorrhage (SAH), leading to neurological and cognitive deficits. The clinical significance of enlarged perivascular spaces (EPVS) on aSAH (aneurysm subarachnoid hemorrhage) outcomes was unclear. Our aim was to explore the association between EPVS and the clinical outcomes of aSAH.

Purchasing or leasing? Equipment upgrades for a capital-constrained manufacturer.

Purchasing and leasing are two main methods to implement equipment upgrades, which can reduce production costs and facilitate manufacturing transformation. In practice, small and medium-sized manufacturers have insufficient cash to balance equipment upgrades and daily production. Under a two-stage setting, this study examines a pull supply chain consisting of a capital-constrained manufacturer and a retailer, where the manufacturer can borrow bank loans.

WDR36 Regulates Trophectoderm Differentiation During Human Preimplantation Embryonic Development Through Glycolytic Metabolism.

Mammalian pre-implantation development is a complex process involving sophisticated regulatory dynamics. WD repeat domain 36 (WDR36) is known to play a critical role in mouse early embryonic development, but its regulatory function in human embryogenesis is still elusive due to limited access to human embryos. The human pluripotent stem cell-derived blastocyst-like structure, termed a blastoid, offers an alternative means to study human development in a dish.

Life-history traits trade-off in gecko (Gekko japonicus) under the influence of climate warming and spirotetramat: Different adaptations to stressors in female and male.

Global warming and rising surface temperatures are adversely affecting organisms. As the use of pesticides increases, concerns about their impacts on non-target organisms are growing. However, climate warming and pesticides may interact to produce combined effects on organisms.

Genome-wide association and transcriptomic analysis and the identification of growth-related genes in Macrobrachium nipponense.

Macrobrachium nipponense is a commercially important freshwater species of prawn that is widely distributed across Asian countries. In order to investigate the molecular mechanisms of growth in M. nipponense, and to provide a foundation for molecular breeding, we used genome-wide association analysis (GWAS) and transcriptomic analysis to screen polymorphisms and genes related to growth traits.