[Studies on dynamic changes of proportions of Tc1 and Tc2 cells during Schistosoma japonicum infection].

Objective: To observe the dynamic changes of the proportions of T cytotoxic type 1 (Tc1) cells and T cytotoxic type 2 (Tc2) cells and analyze the correlation of them with the dynamic changes of the proportions of Th1 and Th2 cells in T lymphocytes respectively at different stages after Schistosoma japonicum infection.

Method: Splenocytes were prepared from spleens of mice with S. japonicum infection at different stages (0, 3, 5, 8, 13 weeks), and the proportions of Tc1, Tc2 and Th1, Th2 cells in T cells were determined by FACS, respectively.

Primary malignant fibrous histiocytoma of the abdominal cavity: CT findings and pathological correlation.

Aim: To study computed tomography (CT) features of abdominal malignant fibrous histiocytoma (MFH) in various rare locations.

Methods: We retroprospectively identified cases of MFH involving the abdominal cavity. Particular attention was paid to details regarding imaging features and histological types.

[Study on the optical properties of ultra-thin metal films in the THz band].

Thin metal films are good candidates of terahertz detectors, reflectors, waveguides and terahertz quantum-cascade lasers (THz-QCLs). The optical parameter is the basis not only for designing the THz components but also for developing novel optoelectronic materials. In the present paper, the complex refractive indices of the ultra-thin metal (Cr, Ni and Ti) films in the THz band were obtained by the THz differential time-domain spectroscopy.

[Fabrication of silver ordered nanoarrays SERS-active substrates and their applications in bladder cancer cells detection].

Highly ordered silver nanopore and nanocap arrays, which were used as surface-enhanced Raman scattering active (SERS-active) substrates, were fabricated by electron-beam evaporating silver on the surface of porous layer and barrier layer of porous anodic alumina (PAA) membranes, respectively. The SERS characteristics of the SERS-active substrates were tested with bladder cancer cells as molecular probe. The results indicated that both the SERS-active substrates displayed a strong SERS enhancement effect.

Electron mobilities of n-type organic semiconductors from time-dependent wavepacket diffusion method: pentacenequinone derivatives.

The electron mobilities of two n-type pentacenequinone derivative organic semiconductors, 5,7,12,14-tetraaza-6,13-pentacenequinone (TAPQ5) and 1,4,8,11-tetraaza-6,13-pentacenequinone (TAPQ7), are investigated with use of the methods of electronic structure and quantum dynamics. The electronic structure calculations reveal that the two key parameters for the control of electron transfer, reorganization energy and electronic coupling, are similar for these two isomerization systems, and the charge carriers essentially display one-dimensional transport properties. The mobilities are then calculated by using the time-dependent wavepacket diffusion approach in which the dynamic fluctuations of the electronic couplings are incorporated via their correlation functions obtained from molecular dynamics simulations.

Assay and characterization of an osmolarity inducible promoter newly isolated from Bacillus subtilis.

An osmolarity-sensitive promoter fragment, P23423, isolated from Bacillus subtilis was characterized. The expression of β-galactosidase (β-Gal) driven by P23423 was regulated by osmolarity both in Escherichia coli and B. subtilis.

[Cost-benefit analysis of comprehensive parasitic disease control project in Rongxian County, Guangxi Zhuang autonomous region].

Objective: To evaluate the cost-benefit of comprehensive parasitic disease control project in Rongxian County of Guangxi, so as to provide the evidence for formulating the control strategy of soil-transmitted nematode.

Methods: The data of the overall input and output for soil-transmitted nematode control were collected from 2007 to 2009, and the cost-benefit was analyzed.

Results: The infection rates of soil-transmitted nematode dropped from 30.

[Correlative analysis between CT pancreatic inflammatory infiltration degree and clinical disease severity of severe acute pancreatitis].

Objective: To investigate the correlation between CT pancreatic inflammatory infiltration degree of severe acute pancreatitis (SAP) and the clinical disease severity, and to explore its prognostic value.

Methods: One hundred and nineteen (83) patients with confirmed diagnosis of SAP during 2008-2010 in West China Hospital of Sichuan University were retrospectively included into the study. Contrast-enhanced multi-detector-row CT (including dual source CT) scan was performed for all the patients.

[Correlation analysis of computed tomography imaging scoring to the presence of acute kidney injury in severe acute pancreatitis].

Objective: To investigate the multi-detector-row spiral CT (MDCT) imaging findings of severe acute pancreatitis (SAP) complicated with acute kidney injury (AKI), and to evaluate the correlation of MDCT imaging scoring to the presence of AKI in SAP.

Methods: One hundred and nineteen patients with confirmed diagnosis of SAP during March 2008-December 2010 in our hospital were retrospectively included into the study. The imaging features including pancreatic size, areas and degrees of pancreatic necrosis, peripancreatic retroperitoneal and intraperitoneal inflammation and other organs involvement (liver, kidney, spleen, gastrointestinal tract, etc.

Construction of a high density integrated genetic map for cucumber (Cucumis sativus L.).

The high-density consensus map was constructed based on the GY14 × PI 183967 map from an inter-subspecific cross and the extended S94 × S06 map from an intra-subspecific cross. The consensus map was composed of 1,369 loci, including 1,152 SSR loci, 192 SRAP loci, 21 SCAR loci and one STS locus as well as three gene loci of fruit external quality traits in seven chromosomes, and spanned 700.5 cM, of which 682.

[Experimental study of liver injury in rats of abdominal infection with abdominal compartment syndrome].

Objective: To evaluate the liver injury in rats of abdominal infection complicated with abdominal compartment syndrome(ACS).

Methods: SD rats were divided into four groups, including the sham group, the abdominal infection group, the ACS group, and the abdominal infection plus ACS group (combination group). Rats were sacrificed at 1 h, 6 h, 12 h, 24 h after operation with 6 rats at each time point.

Spatial pattern analysis of heavy metals in Beijing agricultural soils based on spatial autocorrelation statistics.

This study explored the spatial pattern of heavy metals in Beijing agricultural soils using Moran's I statistic of spatial autocorrelation. The global Moran's I result showed that the spatial dependence of Cr, Ni, Zn, and Hg changed with different spatial weight matrixes, and they had significant and positive global spatial correlations based on distance weight. The spatial dependence of the four metals was scale-dependent on distance, but these scale effects existed within a threshold distance of 13 km, 32 km, 50 km, and 29 km, respectively for Cr, Ni, Zn, and Hg.

[Acute effects of IL-1β on sodium current in cortical neurons of rats].

Interleukin-1β (IL-1β) is an important proinflammatory cytokine that plays a key role in injuries and diseases of the central nervous system (CNS). The voltage-gated Na(+) channel is the most important ion channel of neurons, and is essential for regenerative action potential (AP). The Na(+) channel also contributes to many diseases of the brain.

Chronic administration of Liu Wei Dihuang protects rat's brain against D-galactose-induced impairment of cholinergic system.

This study was aimed to investigate the protective effect of Liu Wei Dihuang (LWDH) against D-galactose (D-gal)-induced brain injury in rats and the existence of sex-dependent differences in LWDH protection. Sixty-four rats evenly composed of males and females were randomly assigned into 4 groups (n = 8): normal saline (NS) + NS (N + N), NS + LWDH (N + L), D-gal + NS (D + N) and D-gal + LWDH (D + L) groups. Rats in D + N and D + L groups received daily injection of D-gal (100 mg/kg, s.

[Open abdomen management treatment of liver injury in rats with abdominal compartment syndrome and sepsis].

Objective: To evaluate the open and closed management treatment of liver injury in rats with sepsis and abdominal compartment syndrome (ACS).

Methods: The sepsis and ACS rats (n = 72) were randomized divided into two groups. One group used closed management (n = 36), the other accepted the open abdomen management (n = 36).

Neuroprotective effect of Jatrorrhizine on hydrogen peroxide-induced cell injury and its potential mechanisms in PC12 cells.

The neuroprotective effects of Jatrorrhizine from Coptidis Rhizoma against hydrogen peroxide (H(2)O(2))-induced rat pheochromocytoma line PC12 injury and its potential mechanisms were evaluated in the present study. When cells were exposed to H(2)O(2) (200 μM) for 12h, there was a significant reduction in cell survival and activity of antioxidant enzyme (SOD and HO-1) and LDH release. In addition, increased ROS production, declined MMP and increased production of malondialdehyde (MDA) were observed.

[Interleukin-1β inhibits the amplitudes of voltage-gated Na(+) currents and action potential in cultured cortical neurons of rat].

Interleukin-1β (IL-1β) is an important proinflammatory cytokine and plays key roles in physiological and pathophysiological processes of central nervous system (CNS). The voltage-gated Na(+) channels are essential for electrical properties of excitable cells and control the excitability and action potential (AP) of neurons. Recent studies have showed the relationship between IL-1β and voltage-gated channels.

[Toll-like receptors and their role in pathogenesis and vaccine study of cutaneous diseases].

Toll like receptor (TLR) can specifically recgnize pathogen-associated molecular patterns (PAMPs) and is considered as an important link between innate and adaptive immunity. It has been shown that TLR plays an important role in the pathogenesis and pathophysiology of a variety of skin diseases. Moreover, TLR agonists have exhibited promising therapeutic effects on the disease models and are expected to be novel vaccine adjuvants.

KAI1 inhibits HGF-induced invasion of pancreatic cancer by sphingosine kinase activity.

Background: KAI1/CD82 has been reported to attenuate the process of metastases in a variety of tumors; however, its mechanism of action in invasion has not been fully elucidated. The present study aimed to investigate the importance of KAI1 in invasion and its correlation with activation of sphingosine kinase (SPK) in human pancreatic cancer PANC1 and Miapaca-2 cell lines.

Methods: The expression of KAI1 in PANC1 and Miapaca-2 cells, which was mediated by recombinant adenovirus (Ad-KAI1), was assessed by a flow cytometer and Western blotting.

Gut bacteria alteration in obese people and its relationship with gene polymorphism.

Aim: To investigate the differences in cultivable gut bacteria and peroxisome proliferator-activated receptor γ2 (PPAR-γ2) gene Pro12Ala variation in obese and normal-weight Chinese people.

Methods: Using culture methods, the amounts of Escherichia coli, Enterococci, Bacteroides, Lactobacilli, Bifidobacteria and Clostridium perfringens (C. perfringens) in the feces of 52 obese participants [body mass index (BMI): ≥ 28 kg/m(2)] and 52 participants of normal-weight (BMI: 18.

Expression and clinicopathologic significance of glypican 3 in hepatocellular carcinoma.

Glypican 3 (GPC3) is a glycosylphosphatidylinositol-anchored membrane protein and plays an important role in regulation of cell growth, differentiation, and migration. The aims of this study were to investigate the expression of GPC3 in human liver, biliary tract, and pancreatic tumors and to evaluate its diagnostic role in differentiating hepatocellular carcinoma (HCC) from other hepatic mimickers. Immunohistochemistry was performed on a large collection of surgically resected samples from 941 primary liver tumors, 50 metastatic adenocarcinomas, and 30 normal livers as well as primary adenocarcinomas of the pancreas (n = 17), gallbladder (n = 30), and extrahepatic bile duct (n = 20).

[Infinite optical thickness of dentine porcelain of IPS E.max A color series].

Objective: To determine the infinite optical thickness of dentine porcelain of IPS E.max A color series.

Methods: Cylindrical dentine porcelain specimens of the IPS E.

Cdk1 is required for the self-renewal of mouse embryonic stem cells.

Cyclin-dependent kinase 1 (Cdk1) is indispensible for the early development of the embryo. However, its role in maintaining the undifferentiated state of the embryonic stem (ES) cells remains unknown. In this study, we dissected the function of Cdk1 in mouse ES cells by RNA-interference and gene expression analyses.

[A matched case-control study on the risk factors of burn injury among primary and secondary school students in Guangzhou].

Objective: To investigate the relative factors of burn injury among primary and secondary school students in Guangzhou and to provide scientific evidence for intervention.

Methods: 1:1 case-control study was conducted in 428 cases and 428 controls based on different sex and classes. The relationship between relative factors and burn injury was analyzed by univariate and multivariate conditional logistic regression.

Application of contrast-enhanced ultrasonography after radiofrequency ablation for renal cell carcinoma: is it sufficient for assessment of therapeutic response?

Purpose: To assess the efficacy of contrast-enhanced ultrasonography (CEUS) with Sonovue in the evaluation of therapeutic response to radiofrequency ablation (RFA) of renal cell carcinoma (RCC).

Materials And Methods: In a recent 3 years, 63 patients (mean age, 60 years; range 26-81 years) with 64 RCCs were treated by RFA. The lesions had a diameter between 1.