The research, which was a component of a broader initiative, focused on synthesizing a pioneering carrier buffer particularly intended for arc atomic emission spectroscopy. By analyzing various evaporation curves and quickly refining the formula of the novel carrier buffer, a more comprehensive, selective, and expedited condition was established for fractionating the target elements from the sample using the single-electrode carrier distillation method, thereby increasing the sensitivity of atomic emission spectrum analysis. Furthermore, the buffer mechanism was thoroughly investigated, using data from field emission scanning electron microscopy (SEM), X-ray powder diffraction (XRD), and energy-dispersive spectrometry (EDS).
View Article and Find Full Text PDFThorac Cancer
December 2024
Tracheal obstruction can arise from multiple conditions, including chronic obstructive pulmonary disease, asthma, foreign bodies, tumors, and acute heart failure. We report a case of a 43-year-old man with cervical liposarcoma who, following surgical excision, chemotherapy, and radiation, presented with severe dyspnea and was admitted to our hospital. A CT scan detected an endotracheal mass causing significant obstruction, suspected to be malignant.
View Article and Find Full Text PDFQuant Imaging Med Surg
December 2024
Background: Stenting is a common approach for treating idiopathic intracranial hypertension (IIH) and venous sinus stenosis (VSS). However, studies comparing stenting with balloon angioplasty alone are lacking. This study sought to compare the clinical efficacy of balloon angioplasty and stenting in the treatment of IIH and VSS.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
December 2024
The medical devices are subjected to dynamic loads and surrounding physiological condition of the bodily fluids, which will impact the degradation behavior of magnesium (Mg) alloy implants. In this work, the corrosion fatigue (CF) and corrosion behaviors of Mg-xGa (x = 1, 1.5, and 2 wt%) alloys in Hank's balanced salt solutions (HBSS) with 1 g/L and 3 g/L glucose are thoroughly studied.
View Article and Find Full Text PDFCadmium (Cd) is a heavy metal recognized for its notable biotoxicity. Excessive Cd levels can have detrimental effects on crop growth, development, and yield. Real-time, rapid, and nondestructive monitoring of Cd content in leaves (LCd) is essential for food security.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Background: Long noncoding RNA (lncRNA) is a significant component of the noncoding genome and refers to RNA molecules that exceed 200 nucleotides in length. It plays a crucial role in both promoting and suppressing cancer by regulating the proliferation, invasion, and metastasis of tumor cells. We have found a correlation between cancer susceptibility candidate 11 (CASC11) experssion and tumorigenesis development prognosis in a number of studies on tumors.
View Article and Find Full Text PDFThe design of a protective electron-rich surface is an ideal route to enhance the performance of catalysts. Due to the higher work function of NiB, facile-directed electron transport occurs from PtNi to NiB to enrich electron density on the surface of the NiB shell. This process increases hydrogen adsorption-desorption kinetics and mitigates Cl corrosion.
View Article and Find Full Text PDFPurpose: Patients with KRAS mutant non-small cell lung cancer (NSCLC) have limited therapeutic options. Based on activity of nuclear export inhibition in preclinical models, we evaluated this strategy in previously treated advanced KRAS mutant NSCLC.
Patients And Methods: The primary outcome of this multi-center phase 1/2 dose escalation trial of selinexor plus docetaxel was safety and tolerability.
Aerogels are widely applied for construction, aerospace, military, and energy owing to their lightweight, high specific surface area, and high porosity. The high porosity of aerogels often leads to a lack of mechanical strength, which limits their applications. Here, this study reports a mechanically robust MXene/cellulose nanocrystal composite aerogel enabled by inducing dense bridging through salting-out.
View Article and Find Full Text PDFIntroduction: To prepare a gelatin methacryloyl (GelMA) hydrogel scaffold embedded with adrenomedullin (ADM) and investigate its impact and underlying mechanisms in endogenous pulp regeneration.
Methods: ADM was evenly distributed within the GelMA hydrogel through a simple and conventional physical mixing technique. The scaffold underwent characterization via scanning electron microscopy, alongside assessments of swelling, degradation, and release properties.
Stroke is a major global cause of death and disability, with ischemic stroke being the most common type. The disruption of the blood-brain barrier (BBB) is a key factor in the pathophysiology of ischemic stroke, allowing immune cells to infiltrate and worsening neuroinflammation. This study uses single-cell RNA sequencing (scRNA-seq) to examine the transcriptional changes in neutrophils, endothelial cells, and T cells during ischemic stroke.
View Article and Find Full Text PDFJ Nanobiotechnology
November 2024
Radionuclide therapy (RT) is widely used to advanced local cancers. However, its therapeutic efficacy is limited to the radiation resistance of cancer cells. Combination therapy aims to circumvent tumor resistance, and the combination of RT with photothermal therapy (PTT), photodynamic therapy (PDT), chemotherapy (CMT), and immunotherapy has shown promising treatment outcomes.
View Article and Find Full Text PDFDriven by the "Internet of Everything" (IoE) vision, the demand for smart materials is growing. Wood, one of the most abundant and renewable resources, has long been a staple in construction and furnishing applications. To further expand its application range, this study developed a high-strength, stable wood-based triboelectric material through a synergistic biphasic mechanism.
View Article and Find Full Text PDFAccurate light source calibration is critical in numerous applications including physics-based computer vision and graphics. We propose an image-based method for calibrating non-isotropic point light sources, addressing challenges posed by their non-radially symmetric radiant intensity distribution and the non-Lambertian properties of the calibration target. We deduce an image formation model, and capture the intensity of the calibration target at multiple poses, coupled with accurate 3D geometry acquisition using the digital fringe projection technique.
View Article and Find Full Text PDFBackground: Cardiac fibrosis is common in myocardial infarction (MI), leading to progressive cardiac dysfunction. Studies suggested that the abnormal N-methyladenosine (mA) modification induced by fat mass and obesity protein (FTO) is vital in MI. However, the effects of FTO on post-infarction cardiac fibrosis have not been detected.
View Article and Find Full Text PDFIn the construction of new power systems, the traditional network security protection mainly based on boundary protection belongs to static defense and still relies mainly on manual processing in vulnerability repair, threat response, etc. It is difficult to adapt to the security protection needs in large-scale distributed new energy, third-party aggregation platforms, and flexible interaction scenarios with power grid enterprise systems. It is necessary to conduct research on dynamic security protection models for IoT and other Blockchain-based IoT architectures.
View Article and Find Full Text PDFPyroptosis is a form of inflammatory cell death that has been demonstrated to trigger anti-tumor immune responses. Photodynamic therapy (PDT) is an innovative non-invasive treatment for tumors that effectively destroys tumor cells and boosts anti-tumor immune response. The ability of PDT to trigger pyroptosis and its mechanism of action are yet uncertain.
View Article and Find Full Text PDFPhotobiomodulation (PBM) is a non-invasive neuromodulation technique for the brain. Low-intensity near-infrared light (1-500 mw) has demonstrated the ability to improve memory in Alzheimer's disease (AD) model mice, suggesting its potential for AD treatment. However, the impact of PBM on neural oscillations in the hippocampal region affected by AD remains unknown.
View Article and Find Full Text PDFMultimodal therapy based on nanozyme is expected to become a novel option for tumor treatment. However, the catalytic efficiency of nanozymes and the hypoxia microenvironment of tumors limit the therapeutic effect of nanozymes. Herein, we screened a small molecule of midazole-2-carboxaldehyde (ICA) to prepare ZIF-90 and embedded gold and platinum nanoparticles to obtain ZAAP.
View Article and Find Full Text PDFBackground: Esomeprazole use is increasing in dogs, but the gastrointestinal adverse events associated with q12h dosing necessitate pharmacodynamic evaluation of a reduced dose and frequency of administration.
Objectives: To compare the efficacy of 2 doses of (q24h) esomeprazole in raising intragastric pH in dogs.
Animals: Nine healthy, client-owned dogs, >20 kg.
Background: This systematic review compared the efficacy of traditional Chinese medicine (TCM) treatments for outcomes of different stages and labor pain among pregnant women.
Methods: Eight databases were electronically searched for TCM on labor pain between January 2012 and January 2022. The studies were recorded and screened according to inclusion criteria and subsequently entered in Note Express.