Publications by authors named "Zhang Meixian"

Introduction: Straw pellet ration replacing part of silage is of great significance for farmers to save farming costs and solve the lack of feed resources. A comprehensive analysis of rumen microbial and serum metabolite compositions is conducted to promote the development of the modern breeding cows-feeding industry.

Methods: In this study, 18 healthy 2-year-old Simmental breeding cows weighing 550 ± 20 kg were selected and randomly divided into two groups.

View Article and Find Full Text PDF

Unlabelled: Some individuals experience unexplained, persistent, or newly developed symptoms after coronavirus disease 2019 (COVID-19), known as post-COVID-19 condition (PCC). We explored the age-related prevalence, symptoms, and associated factors for PCC in children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This prospective cohort study enrolled children with SARS-CoV-2 infection between December 7, 2022, and January 31, 2023.

View Article and Find Full Text PDF

Objectives: Currently, overweight/obesity rates among children are increasing. Moreover, parents generally misunderstand their children's weight status. The correct perception of overweight/obesity in early childhood is very important for children's growth and development.

View Article and Find Full Text PDF

Introduction: The gut microbiota significantly influences the host's production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.

Methods: In this study, five adult male Tianzhu white yaks (4.5 years old) were selected and fed under the same nutritional conditions.

View Article and Find Full Text PDF

Background: Gestational hypertension and preeclampsia are potentially linked to similar pathophysiological processes. Maternal preeclampsia increases the occurrence of early-onset neonatal thrombocytopenia. We hypothesized that maternal gestational hypertension may impact the incident early-onset neonatal thrombocytopenia.

View Article and Find Full Text PDF

Background: Nurses who experience verbal abuse often report negative emotions, which can affect their work status and nurse-patient relationship. However, to the best of our knowledge, no study has summarized the prevalence of verbal abuse among nurses by different perpetrators and related risk factors.

Aim: This review aimed to synthesize the prevalence of verbal abuse among nurses and identify the most common sources and related risk factors.

View Article and Find Full Text PDF

As an indigenous species on the Tibetan Plateau, the yak is well adapted to the plateau hypoxic environment. The high-altitude hypoxia adaptation of the yak requires the adaptive reshaping of multiple tissues and organs, especially the lungs. To reveal the adaptive development of yak lungs under hypoxic stress at the tissue and molecular levels, we conducted histomorphological observations as well as transcriptomic and metabolomic studies of yak lungs at three ages (0.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aims to investigate the mechanisms behind perioperative neurocognitive dysfunction (PND) after anesthesia and surgery by identifying key genes involved in this process.
  • - Researchers conducted experiments on mice to analyze the effects of surgery on gene expression and found 521 differentially expressed genes (DEGs), with four hub genes linked to cognitive decline associated with surgery.
  • - Results indicated that endoplasmic reticulum (ER) stress due to surgery contributes to cognitive impairment and neuroinflammation; preoperative treatment with Tauroursodeoxycholic acid (TUDCA) mitigated these effects by alleviating ER stress and inflammation.
View Article and Find Full Text PDF

Objectives: Low-dose computed tomography (LDCT) has emerged as a pivotal tool for detecting lung cancer among ever-smokers. This study aims to evaluate the gender-specific outcomes of LDCT screening within the Chinese never-smoking population.

Methods: We conducted a single-center, retrospective cohort study, which analyzed LDCT screening outcomes for 42,018 asymptomatic participants.

View Article and Find Full Text PDF
Article Synopsis
  • The plant family is a rich source of medicinal compounds, traditionally used in Chinese medicine for generations.
  • Recent research has highlighted the pharmaceutical potential of alkaloids from these plants, which have diverse biological activities like pain relief, anti-inflammatory effects, and anti-cancer properties.
  • The review aims to explore historical uses of these plants, analyze their alkaloid structures and pharmacological effects, and provide insights for future clinical applications.
View Article and Find Full Text PDF

Aim: This study aimed to discover risk factors for death in patients with critical COVID-19 infection in order to identify patients with a higher risk of death at an early stage.

Methods: We retrospectively analyzed the clinical data of patients with critical COVID-19 infection from April 2022 to June 2022. Data were collected from the electronic medical records.

View Article and Find Full Text PDF

Background: To investigate the relationship between cord blood levels of Angiopoietin-1 (Ang-1) and S-endoglin (sCD105) and bronchopulmonary dysplasia (BPD) in preterm infants.

Methods: Sixty-one preterm infants admitted to the neonatal intensive care unit of the study hospital between July 2021 and September 2022 were included. Cord blood was collected after the birth of premature infants.

View Article and Find Full Text PDF

The objective of this umbrella review was to investigate comprehensive and synthesized evidence of the association between ambient air pollution and obesity based on the current systematic reviews and meta-analyses. Related studies from databases including PubMed, EMBASE, Web of Science, and the Cochrane Library, published before July 16, 2023, were considered in the analysis. All selected systematic reviews and meta-analyses were included in accordance with PRISMA guidelines.

View Article and Find Full Text PDF

Background: Evidence-based medicine (EBM) is the combination of the best research evidence with our clinical expertise, specific situations, and the unique values of our patients. It is essential to evaluate the effectiveness of EBM training for healthcare workers (HCWs).

Objectives: This study aims to assess the impact of EBM training on HCWs' knowledge, attitude, and practice (KAP) related to EBM.

View Article and Find Full Text PDF

Objective: To assess whether carbon monoxide (CO) poisoning increases the incidence of dementia.

Methods: We searched the Cochrane Library, PubMed, and EMBASE from inception to 14 August 2022. Two authors independently selected studies, assessed the quality of included studies, and extracted data.

View Article and Find Full Text PDF

Background: Abusive supervision by the nurse manager significantly influences nurses' withholding voice about patient safety. The role of impression management motivation and speak up-related climate is crucial in understanding their connection. This study aimed to explore the relationship between abusive supervision, impression management motivation, speak up-related climate, and withholding voice about patient safety.

View Article and Find Full Text PDF

Background: Sclerotherapy is purportedly less effective in patients with hemorrhagic than with non-hemorrhagic lymphatic malformations (LMs). We aimed to compare the efficacy of bleomycin-lauromacrogol foam (BLF) sclerotherapy in the treatment of macrocystic LMs with and without intralesional hemorrhage.

Methods: Fifty-five children with macrocystic LMs admitted to the Pediatric Surgery Department were retrospectively included.

View Article and Find Full Text PDF

Background: Chronic airway inflammation and hyperresponsiveness are characteristics of asthma. The isoquinoline alkaloid protopine (PRO) has been shown to exert anti-inflammatory effects, but its mechanism of action in asthma is not known.

Purpose: Investigate the protective properties of PRO upon asthma and elucidate its mechanism.

View Article and Find Full Text PDF

Objective: To explore the effects of using the teach-back method prior to contrast-enhanced magnetic resonance imaging (MRI) on patients' knowledge and satisfaction as well as the clarity of the resulting scans.

Methods: A total of 254 patients who underwent contrast-enhanced MRI examination from July 4, 2022 to September 19, 2022 were enrolled and assigned to the intervention and control groups. Patients in the intervention group received education using the teach-back method, while those in the control group were given routine health education.

View Article and Find Full Text PDF
Article Synopsis
  • A study investigated clinical differences between early-onset and late-onset SARS-CoV-2 infections in neonates, focusing on symptoms, treatments, and outcomes during hospitalization.
  • The research included 58 neonates admitted to the neonatal intensive care unit, with 28% classified as early-onset (within 7 days of birth) and 72% as late-onset (more than 7 days after birth).
  • Findings revealed that late-onset cases were more likely to present with symptoms like fever and cough, and they had a higher incidence of pneumonia, indicating a need for different management strategies for each group.
View Article and Find Full Text PDF

Purpose: We explored the influence of the "Ten new guidelines" on healthcare workers' preparedness, work impact, personal life impact, concerns, and support in Taizhou, China.

Methods: A hospital-based self-administered online survey was conducted to investigate the levels of COVID-19 related experience among healthcare workers in December 2022. In total, 472 out of 2080 healthcare workers (22.

View Article and Find Full Text PDF

Background: Vaccination is the most effective means of preventing outbreaks of infectious diseases, and family ;decision makers play an important role in decision-making regarding family matters and may influence other family members to take an active role in vaccinating children against COVID-19.

Purpose: This study examined the influence of family decision makers on the hesitation of other family members to vaccinate their children against COVID-19.

Methods: A population-based, self-administered online questionnaire was administered in Taizhou, China, from September 1, 2021, to September 15, 2021.

View Article and Find Full Text PDF

Background: Postoperative systemic inflammatory dysregulation (PSID) is characterised by strongly interlinked immune and metabolic abnormalities. However, the hub genes responsible for the interconnections between these two systemic alterations remain to be identified.

Methods: We analysed differentially expressed genes (DEGs) of individual peripheral blood nucleated cells in patients with PSID (n = 21, CRP > 250 mg/L) and control patients (n = 25, CRP < 75 mg/L) following major abdominal surgery, along with their biological functions.

View Article and Find Full Text PDF

The friction and wear tests of high-speed railway braking materials for a variety of braking speeds (600, 400, and 200 rad/min) at 65% and 98% RH RH (RH: relative humidity) were carried out utilizing a friction-testing machine and humidity generator. The research results indicate that braking speeds and ambient humidity have a prominent influence on the friction and wear characteristics of high-speed railway braking materials. At 65% and 98% RH, the lower the braking speed, the lower the wear rate, and the better the wear resistance property of the braking material.

View Article and Find Full Text PDF

Critically ill patients who receive mechanical ventilation after endotracheal intubation commonly experience discomfort and pressure. The major sedative drugs that are currently used in clinical practice present with many complications, such as hypotension, bradycardia, and respiratory depression. Ciprofol (HSK3486), which is a newly developed structural analog of propofol, is a short-acting gamma-aminobutyric acid (GABA) receptor agonist, and its mechanism of action is sedation or anesthesia by enhancing GABA-mediated chloride influx.

View Article and Find Full Text PDF