Publications by authors named "Zhang Linwan"

Carbapenem-resistant (CRKP) of sequence type 11 (ST11) and capsular type KL47 or KL64 are dominant in China. We report the draft genome sequence of an ST11 -carrying CRKP strain belonging to uncommon capsular type KL62. This strain carries virulence factors encoding multiple iron acquisition systems and mucoid regulators.

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Article Synopsis
  • The study focuses on the population structure of the clinically significant pathogen Klebsiella aerogenes through genome analysis of 130 clinical isolates and additional publicly available genomes (1,026 total).
  • Findings reveal that K. aerogenes is a species complex with four phylogroups and highlights two inter-patient transmission events, along with the identification of high-risk clonal clusters that produce carbapenemase, indicating potential treatment challenges.
  • The research uncovers a large number of antimicrobial resistance genes in K. aerogenes and identifies unique genetic features related to virulence, enhancing the understanding of its evolutionary dynamics and public health implications.
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Colonisation by bacterial pathogens typically precedes invasive infection and seeds transmission. Thus, effective decolonisation strategies are urgently needed. The literature reports attempts to use phages for decolonisation.

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Objective: Patients with lung cancer generally undergo minimally invasive surgery, such as video-assisted thoracoscopic surgery (VATS). This study examined the changes in health conditions and symptoms of patients with lung cancer using the European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ) C-30 questionnaires after surgery.

Methods: This was a longitudinal descriptive study.

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As a classical molecular marker, microsatellite (simple sequence repeat, SSR) has been widely used in the study of genetics and evolution of mammals. However, there are widespread problems about lack of comparative analysis and low quality of genomic data. Based on high-quality chromosome-level genomes, we compared the SSR distribution patterns of 81 mammals species belonging to 13 orders in evolution landscape.

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The gut microbiomes of the host are large and complex communities, which helps to maintain homeostasis, improves digestive efficiency, and promotes the development of the immune system. The small mammals distributed in Sichuan Province are the most popular species for biodiversity research in Southwest China. However, the effects of different diets on the structure and function of the gut microbial community of these small mammals are poorly understood.

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Changes in gene expression occur as animals, including primates, age. Macaques have long been used as a model species for primate evolution and biomedical studies. Here, to study gene expression in Tibetan macaques (, TMs) and its differences to humans, we applied RNA-Seq to obtain the blood transcriptomes of 24 TMs.

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