Understanding Post-Translational Modifications in Porcine Reproductive and Respiratory Syndrome Virus Infection.

Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious virus affecting pigs with significant impacts to the swine industry worldwide. This review provides a comprehensive understanding of post-translational modifications (PTMs) associated with PRRSV infection. We discuss the various types of PTMs, including phosphorylation, ubiquitination, SUMoylation, acetylation, glycosylation, palmitoylation, and lactylation, that occur during PRRSV infection.

Estimation of Sow Backfat Thickness Based on Machine Vision.

Controlling the backfat thickness of sows within an appropriate range during different production stages helps to increase the number of pigs weaned per sow per year and ultimately enhances the economic benefit to the pig farm. To obtain the backfat thickness of sows automatically, a backfat thickness estimation method based on machine vision is proposed. First, the backfat thickness values and 3D images of the buttocks of 154 Landrace-Yorkshire crossbred sows were obtained using a veterinary ultrasound backfat meter and Azure Kinect DK camera.

Ethylene negatively regulates cold tolerance through HbEIN3-HbICE2 regulatory module in Hevea brasiliensis.

Cold stress can result in reduced growth rates, decreased latex production, and restricted areas for the Para rubber tree (Hevea brasiliensis). However, the molecular mechanisms governing the response of Hevea brasiliensis to cold stress remain elusive. Here, we found that ethylene plays a negative role in Hevea brasiliensis responses to cold stress.

Investigating DTI-ALPS index and its association with cognitive impairments in patients with alcohol use disorder: A diffusion tensor imaging study.

Background: The glymphatic system, a physiological pathway recently identified, has attracted considerable attention for its potential role in the pathophysiology of neurological disorders. Despite significant research efforts, the exact contribution of the glymphatic system to alcohol use disorder (AUD) remains largely elusive. This study was a secondary analysis by analyzing a subset of the original data to examine changes in the ALPS index and determine its association with cognitive abilities in individuals with AUD.

Unraveling host-pathogen dynamics in a murine Model of septic peritonitis induced by vancomycin-resistant .

Vancomycin-resistant () infection is associated with higher mortality rates. Previous studies have emphasized the importance of innate immune cells and signalling pathways in clearing , but a comprehensive analysis of host-pathogen interactions is lacking. Here, we investigated the interplay of host and in a murine model of septic peritonitis.

Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma.

HBV-associated hepatocellular carcinoma (HCC) represents the prevalent form of HCC, with HBx protein being a crucial oncoprotein. Numerous members of the protein tyrosine phosphatase nonreceptor (PTPN) family have been confirmed to be significantly associated with the occurrence and progression of malignant tumors. Our group previously identified the involvement of PTPN13 in HCC.

Decoupling and Parameter Extraction Methods for Conical Micro-Motion Object Based on FMCW Lidar.

Micro-Doppler time-frequency analysis has been regarded as an important parameter extraction method for conical micro-motion objects. However, the micro-Doppler effect caused by micro-motion can modulate the frequency of lidar echo, leading to coupling between structure and micro-motion parameters. Therefore, it is difficult to extract parameters for micro-motion cones.

SMYD4 monomethylates PRMT5 and forms a positive feedback loop to promote hepatocellular carcinoma progression.

Both lysine and arginine methyltransferases are thought to be promising therapeutic targets for malignant tumors, yet how these methyltransferases function in malignant tumors, especially hepatocellular carcinoma (HCC), has not been fully elucidated. Here, we reported that SMYD4, a lysine methyltransferase, acts as an oncogene in HCC. SMYD4 was highly upregulated in HCC and promoted HCC cell proliferation and metastasis.

Comparison of survival benefit and safety between surgery following conversion therapy versus surgery alone in patients with surgically resectable hepatocellular carcinoma at CNLC IIb/IIIa stage: a propensity score matching study.

Objective: The objective of this study is to evaluate and compare the survival benefit and safety of surgery following conversion therapy versus surgery alone in patients diagnosed with surgically resectable hepatocellular carcinoma (HCC) at China Liver Cancer Staging (CNLC) IIb/IIIa stage.

Methods: A total of 95 patients diagnosed with surgically resectable CNLC IIb/IIIa HCC were retrospectively enrolled in our study from November 2018 to December 2022. Among them, 30 patients underwent conversion therapy followed by hepatectomy, while the remaining 65 received surgery alone.

PE-RASP: range image stitching of photon-efficient imaging through reconstruction, alignment, stitching integration network based on intensity image priors.

Single photon imaging integrates advanced single photon detection technology with Laser Radar (LiDAR) technology, offering heightened sensitivity and precise time measurement. This approach finds extensive applications in biological imaging, remote sensing, and non-visual field imaging. Nevertheless, current single photon LiDAR systems encounter challenges such as low spatial resolution and a limited field of view in their intensity and range images due to constraints in the imaging detector hardware.

China-origin G1 group isolate FPV072 exhibits higher infectivity and pathogenicity than G2 group isolate FPV027.

Introduction: Feline parvovirus (FPV), a single-stranded DNA virus, is accountable for causing feline panleukopenia, a highly contagious and often lethal disease that primarily affects cats. The epidemiology prevalence and pathogenicity of FPV in certain regions of China, however, remains unclear. The aim of this research was to investigate the epidemiology of FPV in different regions of China in 2021 and compare its infectivity and pathogenicity.

Identification of Mudanjiang Phlebovirus in the Daxing'anling Region of China.

Mudanjiang phlebovirus (MJPV) is a newly discovered phlebovirus, initially detected from ticks in China in 2022. In this study, by next-generation sequencing (NGS) on a wide variety of ticks and wild small animals in China, we detected MJPV from and . Additionally, we conducted RT-PCR and sequencing on 1815 adult ticks and 805 wild small mammals collected from eight provinces in China between 2017 and 2021.

HbBIN2 Functions in Plant Cold Stress Resistance through Modulation of HbICE1 Transcriptional Activity and ROS Homeostasis in .

Cold stress poses significant limitations on the growth, latex yield, and ecological distribution of rubber trees (). The GSK3-like kinase plays a significant role in helping plants adapt to different biotic and abiotic stresses. However, the functions of GSK3-like kinase BR-INSENSITIVE 2 (BIN2) in remain elusive.

The application of plant growth-promoting rhizobacteria enhances the tolerance of tobacco seedling to salt stress.

The application of plant growth-promoting rhizobacteria (PGPR) is a novel and an efficient strategy for improving soil degradation and productivity. However, the effect of PGPR on tobacco (Nicotiana tabacum L.) seedling growth under salt stress remains unclear.

Development and validation of web-based prognostic nomograms for massive hepatocellular carcinoma (≥10 cm): A retrospective study based on the SEER database.

Background And Aims: Massive hepatocellular carcinoma (MHCC, a maximum tumor size of at least 10 cm) tends to have a poor prognosis. Therefore, this study aims to construct and validate prognostic nomograms for MHCC.

Methods: Clinic data of 1292 MHCC patients between 2010 and 2015 were got from the surveillance, epidemiology, and end results (SEER) cancer registration database.

Centroid Optimization of DNN Classification in DOA Estimation for UAV.

Classifications based on deep learning have been widely applied in the estimation of the direction of arrival (DOA) of signal. Due to the limited number of classes, the classification of DOA cannot satisfy the required prediction accuracy of signals from random azimuth in real applications. This paper presents a Centroid Optimization of deep neural network classification (CO-DNNC) to improve the estimation accuracy of DOA.

Generated Image Editing Method Based on Global-Local Jacobi Disentanglement for Machine Learning.

Accurate semantic editing of the generated images is extremely important for machine learning and sample enhancement of big data. Aiming at the problem of semantic entanglement in generated image latent space of the StyleGAN2 network, we proposed a generated image editing method based on global-local Jacobi disentanglement. In terms of global disentanglement, we extract the weight matrix of the style layer in the pre-trained StyleGAN2 network; obtain the semantic attribute direction vector by using the weight matrix eigen decomposition method; finally, utilize this direction vector as the initialization vector for the Jacobi orthogonal regularization search algorithm.

Comprehensive analysis of lipid metabolism in influenza virus infection.

Influenza A virus (IAV) exploits host metabolic pathways to support its replication. To improve the understanding of lipid metabolic changes that could occur upon IAV infection, a comprehensive analysis of lipid metabolites in A549 cells infected with the avian H9N2 virus at the different time points was performed. It was found that H9N2 infection could largely promote the level of lipid metabolites.

Object Relocation Visual Tracking Based on Histogram Filter and Siamese Network in Intelligent Transportation.

Target detection and tracking algorithms are one of the key technologies in the field of autonomous driving in intelligent transportation, providing important sensing capabilities for vehicle localization and path planning. Siamese network-based trackers formulate the visual tracking mission as an image-matching process by regression and classification branches, which simplifies the network structure and improves the tracking accuracy. However, there remain many problems, as described below.

Seasonal dynamics in bacterial communities of closed-cage broiler houses.

The bacteria contained in air aerosols from poultry houses are closely connected to animal health and production. This study aimed to investigate the seasonal factors on microbial aerosol concentration, particle size and bacterial spectrum composition inside a closed-cage broiler house. Then, 16S rDNA sequencing technology was applied to analyze the characteristics of bacterial abundance and diversity.