Disordered gold nanoislands-dielectric-metal plasmon reflector for polarization-sensitive color display, humidity sensor and optical memory.

The interaction between ultrafast, tightly focused lasers and materials has garnered significant interest owing to its distinctive properties. In this study, we present a versatile methodology for the fabrication of tunable plasmonic nanostructures by employing a disordered gold nanoisland-dielectric-metal configuration, achieved through femtosecond laser printing. By reshaping the gold nanoislands and reconfiguring them into nanograting-like structures, the orientation of these nanostructures is influenced by the polarization of the femtosecond laser light, leading to controllable plasmon resonance and polarization-sensitive color display.

Efficient removal of anionic dye congo red by Chitosan/Poly (dimethyl diallyl ammonium chloride-co-acrylamide) composite hydrogel.

Chitosan, as a natural and environmentally friendly material, has attracted significant attention in the field of water treatment. In this study, a Chitosan/poly (dimethyl diallyl ammonium chloride-co-acrylamide) composite hydrogel (CPDA hydrogel) featuring a semi-interpenetrating network structure was synthesized via free radical copolymerization for the removal of the anionic dye Congo Red (CR) from wastewater. SEM-EDS, FTIR, XPS, TG, Zeta potential, and mercury intrusion porosimetry (MIP) were employed to analyze the physical and chemical changes in the hydrogel before and after adsorption.

Alternative splicing regulation by tumor suppressing subtransferable candidate 4: a pathway to tumor suppression.

Introduction: RNA splicing is a crucial posttranscriptional process that governs gene expression, and defects in alternative splicing contribute to various diseases, including cancer. Tumor suppressing subtransferable candidate 4 (TSSC4) is a known tumor suppressor and has been identified as part of the U5 small nuclear ribonucleoprotein (snRNP), which is involved in tri-snRNP biogenesis. However, the precise role of TSSC4 in regulating alternative splicing and its impact on tumor growth remain unclear.

Illness Perception and Risk Management Behaviors Among Patients With Gynecologic Cancer at Risk of Lower Extremity Lymphedema.

Background: Patients with gynecologic cancer who undergo lymphadenectomy are at increased risk of lower extremity lymphedema (LEL). They are encouraged to be alert to the possibility of LEL and take risk-management measures throughout life. However, we know little about the perception for LEL and adherence to risk-management measures of Chinese patients with gynecologic cancer.

Identification and characterization of the auxin-response factor family in moso bamboo reveals that PeARF41 negatively regulates second cell wall formation.

Auxin response factors (ARFs) are key transcriptional factors mediating the transcriptional of auxin-related genes that play crucial roles in a range of plant metabolic activities. The characteristics of 47 PeARFs, identified in moso bamboo and divided into three classes, were evaluated. Structural feature analysis showed that intron numbers ranged from 3 to 14, while Motif 1, 2, 7 and 10 were highly conserved, altogether forming DNA-binding and ARF domains.

Pairwise hemorrhage-brain region interaction-driven hemorrhagic stroke assessment in CT.

Hemorrhagic stroke is a major global health problem requiring rapid and accurate diagnosis for effective treatment. Despite advances, current computer-aided diagnosis (CAD) frameworks rarely account for the functional impacts of hemorrhages on specific critical brain regions and lack the detailed assessments essential for precise treatment. To provide detailed insights into hemorrhages, we aim to propose a CAD framework for in-depth hemorrhagic stroke assessment in computed tomography (CT).

Active Sites Regulation and Mass Production of a Hierarchically Porous Fe-N-C Catalyst for Zinc-Air Batteries.

Although the iron-nitrogen-carbon (Fe-N-C) catalyst has great potential in zinc-air batteries (ZABs), the insufficient performance and low production of the Fe-N-C catalyst are still the key factors that greatly limit the commercial application. In this study, first, a simple dual melt-salt template method is developed to prepare the hierarchically porous HPFe-N-C catalyst with abundant highly stable Fe-pyridinic-N sites. Then, HPFe-N-C and Fe-phenanthroline are mixed and heated for the mass production of THPFe-N-C with rich highly active Fe-pyrrolic-N sites.

Global phylogeography and genomic characterization of Vibrio parahaemolyticus infections in Jilin province, China (2016-2022).

Vibrio parahaemolyticus is a critical foodborne pathogen causing gastroenteritis worldwide. The occurrence of transmission and outbreaks attributed to V. parahaemolyticus has exhibited a notable upward trend during the past two decades.

A non-classical view of antibody properties: Allosteric effect between variable and constant regions.

Historically, antibodies have been divided into two functionally independent domains, the variable (V) region for antigen binding and the constant (C) region for mediating effector functions. However, this classical view of antibody function has been severely challenged by a large and growing number of studies, which reveal long-range conformational interactions and allosteric links between the V and C regions. This review comprehensively summarizes the existing studies on antibody allostery, including allosteric conformational changes induced by covalent modifications or noncovalent ligand binding.

CWF19L1 promotes T-cell cytotoxicity through the regulation of alternative splicing.

Effective cancer immunotherapy relies on enhancing the host's immune response, particularly by boosting T cell-mediated cytotoxicity against tumor cells. In this study, we identify CWF19-like cell cycle control factor 1 (CWF19L1) as a novel splicing regulator that enhances T cell-mediated cytotoxicity. CWF19L1 interacts prominently with key splicing factors within the nucleus, including components of the U5 small nuclear ribonucleoprotein and the pre-mRNA processing factor 19 (PRPF19) complex.

Clinical characteristics and associated factors of pediatric acute necrotizing encephalopathy: a retrospective study.

Background: In the clinic, pediatric acute necrotizing encephalopathy (ANE) primarily affects children under five years of age and is characterized by severe brain damage and high mortality. However, some challenges remain regarding the diagnosis and treatment of ANE. In the present study, we analyzed the clinical characteristics and related factors of ANE with the aim of providing improved diagnostic and treatment strategies.

VEGFD/VEGFR3 signaling contributes to the dysfunction of the astrocyte IL-3/microglia IL-3Rα cross-talk and drives neuroinflammation in mouse ischemic stroke.

Astrocyte-derived IL-3 activates the corresponding receptor IL-3Rα in microglia. This cross-talk between astrocytes and microglia ameliorates the pathology of Alzheimer's disease in mice. In this study we investigated the role of IL-3/IL-3Rα cross-talk and its regulatory mechanisms in ischemic stroke.

Diosmin reduces the stability of Snail and Cyclin D1 by targeting FAK to inhibit NSCLC progression.

Background: In different tumours, focal adhesion kinase (FAK), a nonreceptor tyrosine kinase, is upregulated and hence, it represents a promising target for cancer therapy. However, the development of FAK kinase inhibitors has faced a number of challenges. It is therefore imperative that new, effective FAK kinase inhibitors be identified promptly.

A high biocompatible near-infrared fluorescent probe for tracking cysteine in multi-biosystem and its application in cervical cancer imaging.

Cysteine (Cys) plays a crucial role in the biological system and many related diseases. However, the detection of Cys in living organisms are still hindered by shortage of small molecule fluorophores that exhibit excitation and emission in the near-infrared region. Herein, we designed and synthesized a high water-soluble Cys probe (Cy7-SS) based on heptamethine cyanine scaffold.

In vitro digestion and fermentation of the whole goji berry: Bioactive ingredients change and impacts on human gut microbiota.

Goji berry (Lycium barbarum L.) is a nutrient-rich fruit and has received enormous interest for its health benefits. The beneficial effects of goji berry are linked to the absorption of bioactive compounds within the gastrointestinal digestion process and colon fermentation.

The Physical and Psychological Effects of Telerehabilitation-Based Exercise for Patients With Nonspecific Low Back Pain: Prospective Randomized Controlled Trial.

Background: Physical therapy has demonstrated efficacy in managing nonspecific low back pain (NLBP) among patients. Nevertheless, the prevalence of NLBP poses a challenge, as the existing medical infrastructure may be insufficient to care for the large patient population, particularly in geographically remote regions. Telerehabilitation emerges as a promising method to address this concern by offering a method to deliver superior medical care to a greater number of patients with NLBP.

A functional-group-based perspective on the response of marine phytoplankton to mesoscale eddies.

This study analyzed the response of marine phytoplankton to environmental changes induced by mesoscale warm eddies through the lens of functional groups, highlighting the complex interactions within the ecosystem. It was found that warm eddies significantly affected phytoplankton distribution, with cell abundance in the center being only 75.60 cells/L, compared to 1095.

Evaluation of the growth performance, meat quality, and gut microbiota of broilers fed diets containing walnut green husk extract.

This study was conducted to evaluate the effects of walnut green husk extract (WGHe) on the growth performance, meat quality, antioxidative status, gut morphology, and microbiota diversity of broilers. A total of 216 one-day-old broilers were divided into 4 groups, each consisting of 9 replicates (6 birds per replicate) as follows: 1) control group, basal diet; 2) antibiotic group, basal diet supplemented with enduracidin and colistin sulfate; 3) low-dose group, basal diet supplemented with 5.0 g/kg WGHe; and 4) high-dose group, basal diet supplemented with 10.