High-Efficiency, Long-Lifetime and Color-Tunable Hybrid WOLEDs Using a Platinum Complex with Voltage-Dependent Monomer and Aggregate Emission.

Color-tunable white organic light-emitting diodes (CT-WOLEDs) have attracted widespread attention given their large color variation to meet the different daily scenarios from the perspective of circadian rhythm. However, most reported CT-WOLEDs, especially the tri-color devices, exhibit poor performances and sophisticated structures. Here, a simple structure tri-color CT-WOLED is demonstrated that simultaneously exhibits high efficiency, ultralong operation lifetime, and wide color-tunable range for dynamic sunlight emulation.

Acute Niclofolan Intoxication Led to Stillbirth: A Case Report.

Niclofolan is a commonly used veterinary drug worldwide. We reported a case of acute niclofolan intoxication in a pregnant woman. We recorded in detail her toxic symptoms, including nausea, vomiting, asthenia, blurred vision, and aberrant blood values.

Enzymatic activity and gene expression changes in the earthworms induced by co-exposure to beta-cypermethrin and triadimefon.

Pesticides often exist as complex mixtures in soil environments, yet the toxicity of these combinations has not been thoroughly investigated. In light of this, the current study aimed to assess the enzymatic activity and gene expression responses in the earthworm Eisenia fetida when exposed to a mixture of beta-cypermethrin (BCY) and triadimefon (TRI). The findings revealed that co-exposure to BCY and TRI triggered acute synergistic toxicity in E.

Postoperative adjuvant immunotherapy for pathological stage II-IVa esophageal squamous cell carcinoma after radical surgery does not improve disease-free recurrence rates.

Background/objectives: Postoperative adjuvant therapy for esophageal squamous cell carcinoma (ESCC) primarily includes chemotherapy and chemoradiotherapy. The survival benefits of postoperative adjuvant therapy for R0-resected ESCC remain controversial. Immunotherapy is being gradually applied perioperatively for esophageal cancer, but the efficacy of postoperative immunotherapy in ESCC is unclear.

Recent Research Progress of Benzothiazole Derivative Based Fluorescent Probes for Reactive Oxygen (HO HClO) and Sulfide (HS) Recognition.

Fluorescent sensing technology has advantages such as high sensitivity, good selectivity, and easy operation. It is widely used in the environment and biomedical field and receives increasing attention from people. It is easy to modify the structure of the benzothiazole fluorophores, and adding the push-pull electronic system can regulate the optical properties of benzodiapylene molecules.

Starfish-Inspired Solid-State Li-ion Conductive Membrane with Balanced Rigidity and Flexibility for Ultrastable Lithium Metal Batteries.

The performance of solid-state lithium-metal batteries (SSLMB) is often constrained by the low ionic conductivity, narrow electrochemical window, and insufficient mechanical strength of polyethylene oxide (PEO)-based electrolytes. Inspired by the soft-outside, rigid-inside structure of starfish, we designed multifunctional "starfish-type" composite polymer electrolytes (CPEs) using electrospinning technology. These CPEs feature a three-dimensional rigid skeleton network composed of polyacrylonitrile/metal-organic frameworks/ionic liquids (PAN/MOFs/ILs), creating continuous and efficient Li transport channels: MOFs impart rigidity, PEO acts as a cushioning outer layer to enhance interfacial compatibility, and ILs reduce interfacial resistance.

Development and validation of CNN-MLP models for predicting anti-VEGF therapy outcomes in diabetic macular edema.

Diabetic macular edema (DME) is a common complication of diabetes that can lead to vision loss, and anti-vascular endothelial growth factor (anti-VEGF) therapy is the standard of care for DME, but the treatment outcomes vary widely among patients. This study collected optical coherence tomography (OCT) images and clinical data from DME patients who received anti-VEGF treatment to develop and validate deep learning (DL) models for predicting the anti-VEGF outcomes in DME patients based on convolutional neural network (CNN) and multilayer perceptron (MLP) combined architecture by using multimodal data. An Xception-MLP architecture was utilized to predict best-corrected visual acuity (BCVA), central subfield thickness (CST), cube volume (CV), and cube average thickness (CAT).

SENP1 Promotes Caspase-11 Inflammasome Activation and Aggravates Inflammatory Response in Murine Acute Lung Injury Induced by Lipopolysaccharide.

Background: Infection is the leading cause of acute lung injury (ALI). Macrophages, which are pivotal innate immune cells, play a critical role in mediating inflammatory processes. Intracellular lipopolysaccharide (LPS) from invasive Gram-negative bacteria can activate the caspase-11 inflammasome, leading to the induction of pyroptosis in macrophages.

Respiratory system mechanics during noninvasive proportional assist ventilation: A model study.

Purpose: To assess the accuracies of airway resistance (Raw) and compliance (Crs) calculations using the expiratory time constant (RCexp) method as well as the accuracy of Pmus estimation in obstructive lung models.

Methods: A Respironics V60 ventilator was connected to an active lung simulator. The driving pressure was maintained at 5-10 cmH2O and positive end-expiration pressure (PEEP) was 5 cmH2O.

A novel near-infrared fluorescent probe for butyrylcholinesterase: Research for screening of natural anti-AD inhibitors.

Elevated levels of butyrylcholinesterase (BuChE) have the potential to be predictive in the timely detection and diagnosis of Alzheimer's disease (AD). By inhibiting of BuChE activity can raise acetylcholine levels and intervene AD processes. Therefore, BuChE as an important factor in treatment AD has been given more and more attention in clinical studies.

Uncertainty guided semi-supervised few-shot segmentation with prototype level fusion.

Few-Shot Semantic Segmentation (FSS) aims to tackle the challenge of segmenting novel categories with limited annotated data. However, given the diversity among support-query pairs, transferring meta-knowledge to unseen categories poses a significant challenge, particularly in scenarios featuring substantial intra-class variance within an episode task. To alleviate this issue, we propose the Uncertainty Guided Adaptive Prototype Network (UGAPNet) for semi-supervised few-shot semantic segmentation.

A Three-Dimensional Surface-Adaptive Stretchable Sensor for Online Monitoring of Composite Materials Curing.

Recently, rigid sensors have been commonly applied to online monitoring of the core curing processes of composite materials to prevent both overcuring and under-curing. However, conventional rigid sensors are prone to causing cracks and bubbles in composite materials during the curing process, thereby affecting both the mechanical performance and the overall reliability of the materials. Herein, stretchable interdigital dielectric sensors with flexible substrates and electrodes are designed to conform to complex 3D surfaces, thus enabling embedded nondestructive monitoring of composite curing processes.

X-ray ghost imaging with a specially developed beam splitter.

X-ray ghost imaging with a crystal beam splitter has advantages in highly efficient imaging due to the simultaneous acquisition of signals from both the object beam and reference beam. However, beam splitting with a large field of view, uniform distribution and high correlation has been a great challenge up to now. Therefore, a dedicated beam splitter has been developed by optimizing the optical layout of a synchrotron radiation beamline and the fabrication process of a Laue crystal.

Enhancing Spin-Orbit Coupling in an Indolocarbazole Multiresonance Emitter by a Sulfur-Containing Peripheral Substituent for a Fast Reverse Intersystem Crossing.

A fast reverse intersystem crossing (RISC) remains an ongoing pursuit for multiresonance (MR) emitters but faces formidable challenges, particularly for indolocarbazole (ICz) derived ones. Here, heavy-atom effect is introduced first to construct ICz-MR emitter using a sulfur-containing substitute, simultaneously enhancing both spin-orbit and spin-vibronic coupling to afford a fast RISC with a rate of 1.2 × 10 s, nearly one order of magnitude higher than previous maximum values.

Delocalizing electron distribution in thermally activated delayed fluorophors for high-efficiency and long-lifetime blue electroluminescence.

Blue thermally activated delayed fluorescent emitters are promising for the next generation of organic light-emitting diodes, yet their performance still cannot meet the requirements for commercialization. Here we establish a design rule for highly efficient and stable thermally activated delayed fluorescent emitters by introducing an auxiliary acceptor that could delocalize electron distributions, enhancing molecular stability in both the negative polaron and triplet excited state, while also accelerating triplet-to-singlet up-conversion and singlet radiative processes simultaneously. Proof-of-concept thermally activated delayed fluorescent compounds, based on a multi-carbazole-benzonitrile structure, exhibit near-unity photoluminescent quantum yields, short-lived delays and improved photoluminescent and electroluminescent stabilities.

Mechanism of Jizhi syrup's prevention and treatment of acute bronchitis based on LPS-iNOS inflammatory mediators' signalling.

Ethnopharmacological Relevance: Jizhi syrup (JZTJ) is composed of eight medicinal herbs, including Houttuynia cordata, Fagopyrum dibotrys, Ilex chinensis, Ephedra sinica, Aster tataricus, Peucedanum praeruptorum, Citrus aurantium and Glycyrrhiza uralensis. It is mainly used for coughing caused by exogenous wind heat. Symptoms include fever, aversion to cold, chest and diaphragm tightness, cough and sore throat; and acute bronchitis and acute exacerbation of chronic bronchitis with the above symptoms.

Mechanistic insights into CO hydrogenation to methanol on Cu(110): unveiling energy linear relationships and enhancing performance strategies.

The study of energy correlations in catalytic reactions plays a pivotal role in guiding catalyst development. This paper focuses on the investigation of energy linear relationships in methanol synthesis from CO hydrogenation on copper surfaces, systematically exploring energy parameters including activation energy, reaction energy and adsorption energy. A comparative analysis of the adsorption characteristics and reaction parameters in the formate, formic acid and reverse water-gas shift pathways is conducted, laying the data foundation for subsequent linear studies.

Jejunostomy feeding plus oral feeding versus intravenous nutrition plus oral feeding after esophageal cancer resection: a comparative retrospective cohort study.

Background: There are multiple choices for the nutritional management mode after esophageal cancer surgery. Currently, there is still controversy regarding which nutritional management mode has an impact on the postoperative recovery and overall survival (OS) of patients. This study aims to compare the differences between two commonly used clinical nutritional management modes: jejunostomy feeding plus oral intake (JF plus OI) and intravenous nutrition plus oral intake (IN plus OI), in terms of short-term efficacy and 3-year OS, in order to further explore the optimal mode of enteral nutrition management after esophageal cancer surgery.

Whole-Cell Electron Tomography Analysis of Vacuole Biogenesis.

Vacuoles in plant cells are the most prominent organelles that harbor distinctive features, including lytic function, storage of proteins and sugars, balance of cell volume, and defense responses. Despite their dominant size and functional versatility, the nature and biogenesis of vacuoles in plants per se remain elusive and several models have been proposed. Recently, we used the whole-cell 3D electron tomography (ET) technique to study vacuole formation and distribution at nanometer resolution and demonstrated that small vacuoles are derived from multivesicular body maturation and fusion.

Extracellular Vesicle Isolation and Mass Spectrometry-Based Proteomic Analysis in Arabidopsis thaliana.

Extracellular vesicles (EVs) can transport various biological materials, including proteins, lipids, nucleic acids, and metabolites, through the unconventional protein secretion (UPS) pathway. Plant EVs can be classified into at least three major types: tetraspanin 8 (TET8)-positive EVs, penetration 1 (PEN1)-positive EVs, and exocyst-positive organelle (EXPO)-derived EVs. However, the research progress of plant EVs has been hindered due to the limitations inherent in EV isolation techniques.

Lag projective synchronization of discrete-time fractional-order quaternion-valued neural networks with time delays.

This paper deals with the lag projective synchronization (LPS) problem for a class of discrete-time fractional-order quaternion-valued neural networks(DTFO QVNNs) systems with time delays. Firstly, a DTFOQVNNs system with time delay is constructed. Secondly, linear and adaptive feedback controllers with sign function are designed respectively.