Association between sarcopenia and prognosis of hepatocellular carcinoma: A systematic review and meta-analysis.

Background: Sarcopenia, characterized by the loss of muscle mass, strength, and physical ability, occurs with aging and certain chronic illnesses such as chronic liver diseases and cancer. Sarcopenia is common in liver cirrhosis and hepatocellular carcinoma (HCC). Previous reports of association between sarcopenia and prognosis of HCC have been inconsistent.

Targeting ninjurin 2 by miR-764 regulates hydrogen peroxide (HO)-induced neuronal cell death.

Ninjurin 2 (NINJ2) is a novel adhesion molecule expressed in neurons and glial cells. The current study determined if specific microRNA (miRNA) can regulate NINJ2 expression in human neuronal cells. Sequence analysis of NINJ2 mRNA 3'-untranslated region (3'-UTR) revealed that microRNA-764 (miR-764) putatively targets NINJ2.

Chondroitin sulfate from sturgeon bone ameliorates pain of osteoarthritis induced by monosodium iodoacetate in rats.

Chondroitin sulfate (CS) is an important component of the extracellular matrix of cartilage and has been widely used as one of the main drugs for the treatment of joint pain-related nutraceuticals and medicines. Sturgeon bone (SB) is the main waste during deep processing of sturgeons in fishery production. The present study was evaluated the therapeutic effect of CS from SB (CSSB) on monosodium iodoacetate (MIA)-induced osteoarthritis (OA) pain and further explored the potential medicinal value of CSSB.

Association of serum Ninjurin2 levels with neurologic damage and postherpetic neuralgia occurrence: an observational cohort study in chinese herpeszoster patients.

Objectives: Postherpetic neuralgia(PHN) is the most common complication of herpeszoster (HZ) infection. The study aimed to explore whether serum Ninjurin2 (for nerve injury-induced protein 2, NINJ2), a novel neurologic damage related protein, is associated with nerve injury and the occurrence of PHN.

Results: Seventy-four of the eighty patients completed the study.

Comparison of the efficacy and safety between dezocine injection and morphine injection for persistence of pain in Chinese cancer patients: a meta-analysis.

The association between the efficacy and safety of dezocine injection and morphine injection for persistence of pain in patients with cancer had yielded controversial results. Therefore, we conduct a meta-analysis of existing observational published studies to assess the relationship between them among Chinese. We conducted a comprehensive research from the databases of PubMed, Web of Science, and Wan Fang Med Online for the related studies up to October 2016.

Association between selenium intake and the risk of pancreatic cancer: a meta-analysis of observational studies.

Quantification of the association between the intake of selenium and risk of pancreatic cancer is still conflicting. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of selenium intake with the risk of pancreatic cancer. Pertinent studies were identified by a search of PubMed and Web of Knowledge to July 2016.

Pregabalin in the treatment of herpetic neuralgia: results of a multicenter Chinese study.

Objective: The aim of this study was to evaluate the efficacy, impact on quality of life, and safety of pregabalin for the treatment of acute herpetic neuralgia (AHN) and subacute herpetic neuralgia (SHN).

Design: Multicenter, parallel-group, single-blind, 4-week, randomized clinical trial.

Setting: Conducted in the department of pain clinic of participating hospitals.