Light-curing of restorative composite through milled and 3D-printed full-contour zirconia for adhesive luting.

Objectives: To evaluate the effect of different zirconia compositions and manufacturing processes on the light irradiance (LI), to measure the degree of conversion (DC) of solely light-curing restorative composite underneath these zirconia grades and to evaluate the respective zirconia microstructures.

Methods: Six dental zirconia grades (GC HT, GC UHT [GC]; Katana HT, Katana UTML [Kuraray Noritake]; Lava Esthetic, Lava Plus [3 M Oral Care]) were cut and sintered per manufacturer instructions. One 3D-printed zirconia grade (XJet [XJET]) was prepared according to previous research.

Characterization of the wall-associated kinase (WAK) gene family in Gossypium barbadense reveals the positive role of GbWAK5 in salt tolerance.

We characterized the WAK gene family in Gossypium barbadense and revealed the potential function of GbWAK5 in regulating salt tolerance by modulating ion homeostasis. Soil salinization is one of the main factors restricting cotton production. Although the role of the wall-associated kinases (WAKs) in plants has been extensively studied, its response to salt stress in sea-island cotton (Gossypium barbadense L.

Significance of frailty in mortality and complication after hepatectomy for patients with liver cancer: a systematic review and meta-analysis.

Background: Frailty has been associated with increased mortality and complications among liver cancer patients. However, the frailty prevalence and outcomes in frail populations with primary liver cancer have not been systematically validated.

Methods: Embase, PubMed, Scopus, and Web of Science were searched for eligible studies that explored the prevalence and impact of frailty in liver cancers from inception until October 26, 2023.

Remote sensing research on plastics in marine and inland water: Development, opportunities and challenge.

The accumulation of plastic waste from various sources into marine and inland water is considered a global problem due to its serious impacts on aquatic ecosystems and human health. In the past decade, remote sensing has played an important role in monitoring of plastic pollution in marine and inland water sources and has achieved a series of research results in this field. In this study, a comprehensive review was conducted on the development, opportunities, and challenges of datasets and methods in Marine and Inland Water Plastics Remote Sensing (MIWPRS) monitoring over the past decade, based on the Web of Science (WOS) core database.

Evaluation of atmospheric correction algorithms for salt lake water assessment: Accuracy, band-specific effects, and sensor consistency.

Atmospheric correction plays an important role in satellite monitoring of lake water quality. However, different atmospheric correction algorithms yield significantly different accuracy for inland lake waters beset by shallowness and turbidity. Finding a suitable algorithm for a specific lake is critical for quantitative satellite water-environmental monitoring.

Determinants of regioselectivity of heterostructures in cation exchange reactions.

A cation exchange (CE) reaction offers a remarkable opportunity to create versatile metal sulfide nanocrystals (NCs) with arbitrary complexity in composition, structure, and functionality. The concept of regioselectivity has been discovered and developed to build the target heterostructures through CE reactions, yet a general principle of regioselectivity remains unclear. In this work, we establish connections between experimental results and theoretical insights to elucidate the determinants of regioselectivity using designed aliovalent CE reactions on a two-dimensional template.

Co-expression of α-L-rhamnosidase and β-glucosidase in Aspergillus niger and its application in enzymatic production of quercetin.

Quercetin (3,3',4',5,7-pentahydroxy flavonoid) is a bioactive flavonoid with significant medicinal properties. Similarly, Rutin (quercetin-3-O-rutinoside or 3',4',5,7-tetrahydroxy-flavone-3-rutinoside) is widely recognized flavonoid, and is converted to quercetin by α-L-rhamnosidase and β-D-glucosidase. In this study, engineered Aspergillus niger co-expressing α-L-rhamnosidase and β-glucosidase was successfully constructed, and engineered strain Rha1-BGL8 was obtained by enzyme activity assay.

Longitudinally continuous varying high-order cylindrical vector fields enabled by spin-decoupled metasurfaces.

The manipulation of vector optical fields in three-dimensional (3D) space plays a vital role in both fundamental research and practical implementations of polarization optics. However, existing studies mostly focus on 3D vector optical fields with limited modes. Here, an approach of spin-decoupled spatial partitioning is proposed to generate complex 3D vector optical fields with a customizable number of modes on demand.

Dynamic nonlocal metasurface for multifunctional integration via phase-change materials.

Non-local metasurface supporting geometric phases at bound states in the continuum (BIC) simultaneously enables sharp spectral resonances and spatial wavefront shaping, thus providing a diversified optical platform for multifunctional devices. However, a static nonlocal metasurface cannot manipulate multiple degrees of freedom (DOFs), making it difficult to achieve multifunctional integration and be applied in different scenarios. Here, we presented and demonstrated phase-change non-local metasurfaces that can realize dynamic manipulation of multiple DOFs including resonant frequency, values, band, and spatial wavefront.

Deep learning for cross-region streamflow and flood forecasting at a global scale.

Streamflow and flood forecasting remains one of the long-standing challenges in hydrology. Traditional physically based models are hampered by sparse parameters and complex calibration procedures particularly in ungauged catchments. We propose a novel hybrid deep learning model termed encoder-decoder double-layer long short-term memory (ED-DLSTM) to address streamflow forecasting at global scale for all (gauged and ungauged) catchments.

Deciphering the hepatitis E virus ORF1: Functional domains, protein processing, and patient-derived mutations.

Hepatitis E virus (HEV) is a major cause of acute and chronic hepatitis in humans. The HEV open reading frames (ORF1) encodes a large non-structural protein essential for viral replication, which contains several functional domains, including helicase and RNA-dependent RNA polymerase. A confusing aspect is that, while RNA viruses typically encode large polyproteins that rely on their enzymatic activity for processing into functional units, the processing of the ORF1 protein and the mechanisms involved remain unclear.

Pullulan-spermine enhance the tolerance of probiotics and immune stimulation of macrophages.

The application of probiotics as adjunctive therapy in colorectal cancer treatment is hindered by the paucity of strains with specialized functions and the instability of their in vivo efficacy. The design of innovative and simple encapsulation strategies to enhance their stability and efficacy of probiotics has garnered substantial interest. This study investigated four Bifidobacterium longum strains from human feces for tolerance and cytotoxicity, and then synthesized a cationic polysaccharide, pullulan-spermine (PS), for probiotic encapsulation.

High-resolution non-line-of-sight imaging based on liquid crystal planar optical elements.

Non-line-of-sight (NLOS) imaging aims at recovering hidden objects located beyond the traditional line of sight, with potential applications in areas such as security monitoring, search and rescue, and autonomous driving. Conventionally, NLOS imaging requires raster scanning of laser pulses and collecting the reflected photons from a relay wall. High-time-resolution detectors obtain the flight time of photons undergoing multiple scattering for image reconstruction.

The CCL5/CCR5/SHP2 axis sustains Stat1 phosphorylation and activates NF-κB signaling promoting M1 macrophage polarization and exacerbating chronic prostatic inflammation.

Background And Objective: Chronic prostatitis (CP) is a condition markered by persistent prostate inflammation, yet the specific cytokines driving its progression remain largely undefined. This study aims to identify key cytokines involved in CP and investigate their role in driving inflammatory responses through mechanistic and therapeutic exploration.

Methods: A 48-cytokine panel test was conducted to compare the plasma cytokine profiles between participants with CP-like symptoms (CP-LS) and healthy controls.

Harnessing AI for advancing pathogenic microbiology: a bibliometric and topic modeling approach.

Introduction: The integration of artificial intelligence (AI) in pathogenic microbiology has accelerated research and innovation. This study aims to explore the evolution and trends of AI applications in this domain, providing insights into how AI is transforming research and practice in pathogenic microbiology.

Methods: We employed bibliometric analysis and topic modeling to examine 27,420 publications from the Web of Science Core Collection, covering the period from 2010 to 2024.

Upregulation of CRISP3 and its clinical values in adult sepsis: a comprehensive analysis based on microarrays and a two-retrospective-cohort study.

Background: Current lines of evidence indicate that cysteine-rich secretory protein 3 (CRISP3) is an immunoregulatory factor. Nevertheless, no study has explored the relationships between the values of CRISP3 and sepsis.

Methods: We conducted a comprehensive literature search and meta-analysis from the Gene Expression Omnibus (GEO) and ArrayExpress to determine the expression of CRISP3 in sepsis patients.

4-Gbps low-latency FPGA-based underwater wireless optical communication.

In this paper, a high-speed and real-time underwater wireless optical communication (UWOC) system based on orthogonal frequency division multiplexing (OFDM) is designed and demonstrated using the field programmable gate array (FPGA) with a miniaturized demo board designed and made by ourselves. Through the parallel signal processing mode (i.e.

Azopyridine Polymers in Organic Phase Change Materials for High Energy Density Photothermal Storage and Controlled Release.

Azo-compounds molecules and phase change materials offer potential applications for sustainable energy systems through the storage and controllable release photochemical and phase change energy. Developing novel and highly efficient Azo-based solar thermal fuels (STFs) for photothermal energy storage and synergistic cooperation with organic phase change materials present significant challenges. Herein, three types of (ortho-, meta-, and para-) azopyridine polymers hinged with flexible alkyl chain are synthesized, in which meta-azopyridine polymer exhibits striking photothermal storage capacity of 430 J/g, providing a feasibility solution for developing high energy density Azo-based STFs.

The trend, prevalence and potential risk factors of secondary HIV transmission among HIV/AIDS individuals receiving ART in Guangxi, China: a longitudinal cross-sectional study.

Identifying the prevalence and risk factors of secondary human immunodeficiency virus (HIV) transmission from people living with HIV (PLWH) to other people is crucial for ending the HIV epidemic. However, the data among antiretroviral therapy (ART) patients is limited. This study aims to assess the prevalence and risk factors of secondary HIV transmission among PLWH receiving ART by longitudinal molecular networks in China.

Metabolomic Analysis of Exposed to UV-B Radiation Stress.

Plants cultivated on the Qinghai-Tibet Plateau (QTP) are exposed to high ultraviolet radiation intensities, so they require effective mechanisms to adapt to these stress conditions. UV-B radiation is an abiotic stress factor that affects plant growth, development, and environmental adaptation. is a common species in the alpine meadows of the QTP, with high-stress resistance, large biomass, and high nutritional value.

Insights into the genetic architecture of the reciprocal interspecific hybrids derived from and .

Unlabelled: Chrysanthemums are versatile ornamental plants, and improving leaf and flower traits is an important breeding objective. Distant hybridization is a powerful method for plant breeding and genetic improvement, whereas the genetic basis in interspecific F progeny of chrysanthemums needs to be better understood for breeding purposes. In this study, the leaf and floral traits of the 273 reciprocal interspecific F hybrids of diploid (YSJ) and (JHN) were analyzed along with their SNP-derived genetic structure to elucidate the influence of differences in genetic background between the parents on the hybrid performance.