Study on biogenic acid-mediated enhanced leaching of lepidolite by Aspergillus niger based on transcriptomics.

The synergistic effect between microorganisms with different modes of action can improve the leaching efficiency. In this study, biogenic acid was extracted from bacterial metabolites to induce fungal secretion, strengthen fungal leaching, and reveal the microscopic mechanism of biogenic acid stimulating fungal metabolic synthesis through transcriptome analysis. The results showed that the addition of biogenic acid increased the biomass and metabolic activity of Aspergillus Niger, changed the secretion of extracellular polymeric substances, enhanced the dissolution of mineral surface, and increased the leaching rate.

Feasibility study of YSO/SiPM based detectors for virtual monochromatic image synthesis.

Background: The development of photon-counting CT systems has focused on semiconductor detectors like cadmium zinc telluride (CZT) and cadmium telluride (CdTe). However, these detectors face high costs and charge-sharing issues, distorting the energy spectrum. Indirect detection using Yttrium Orthosilicate (YSO) scintillators with silicon photomultiplier (SiPM) offers a cost-effective alternative with high detection efficiency, low dark count rate, and high sensor gain.

Feasibility study of photon-counting CT for material identification based on YSO/SiPM detector: A proof of concept.

Background: Current photon-counting computed tomography (CT) systems utilize semiconductor detectors, such as cadmium telluride (CdTe), cadmium zinc telluride (CZT), and silicon (Si), which convert x-ray photons directly into charge pulses. An alternative approach is indirect detection, which involves Yttrium Orthosilicate (YSO) scintillators coupled with silicon photomultipliers (SiPMs). This presents an attractive and cost-effective option due to its low cost, high detection efficiency, low dark count rate, and high sensor gain.

Sub-bundle based analysis reveals the role of human optic radiation in visual working memory.

White matter (WM) functional activity has been reliably detected through functional magnetic resonance imaging (fMRI). Previous studies have primarily examined WM bundles as unified entities, thereby obscuring the functional heterogeneity inherent within these bundles. Here, for the first time, we investigate the function of sub-bundles of a prototypical visual WM tract-the optic radiation (OR).

Synergistic enzymatic mechanism of lepidolite leaching enhanced by a mixture of Bacillus mucilaginosus and Bacillus circulans.

Numerous studies have demonstrated that the co-leaching of ores by different silicate bacteria significantly improves the performance of bioleaching systems. Nevertheless, the mechanism of different silicate bacteria synergistically or complementarily enhanced the leaching process of lithium-containing silicate remains unclear. This study discussed the leaching impact of the combined presence of two metabolically distinct silicate bacteria on lepidolite, with the aim of comprehending the synergistic effect resulting from the presence of Bacillus mucilaginosus and Bacillus circulans in the leaching process.

Effects of single and combined contamination of total petroleum hydrocarbons and heavy metals on soil microecosystems: Insights into bacterial diversity, assembly, and ecological function.

Deciphering the impact of single and combined contamination of total petroleum hydrocarbons (TPH) and heavy metals on soil microecosystems is essential for the remediation of contaminated habitats, yet it remains incompletely understood. In this study, we employed high-throughput sequencing to investigate the impact of single TPH contamination, single metal contamination, and their co-contamination on soil microbial diversity, assembly mechanisms, composition, ecological function, and resistome. Our results revealed that contamination led to a reduction in alpha diversity, with single contamination displaying lower diversity compared to co-contamination, depending on the concentration of pollutants.

Thiophene-based porphyrin polymers for Mercury (II) efficient removal in aqueous solution.

Development of novel sulf-functionalized porous organic polymers (POPs) for Mercury (II) (Hg) removal is of great significant, but the adsorbents always suffered by the low adsorption capacity, stability, and efficiency for the reason that the common construction of functionalized POPs from the functionalized monomers or post-functionalization of the POPs always sacrifice the porosity. In this paper, porphyrin-based POPs with different heteroatoms were constructed through the aldehyde monomer (benzene, 2,5-thiophenedicarboxaldehyde and thieno[3,2-b]thiophene-2,5-dicarboxaldehyde) and pyrrole according to the Adler-Longo method. In this way, nitrogen (N) in pyrrole and sulfur (S) in thiophene structures were embed into the backbone structure of the polymers.

Comparing efficacy and factors of postoperative bleeding in endoscopic mucosal resection vs coagulation for intestinal polyps.

This study aimed to assess the effectiveness of Endoscopic Mucosal Resection (EMR) and Argon Plasma Coagulation (APC) as therapeutic approaches for intestinal polyps in patients, and to examine the factors associated with postoperative bleeding. This study included 132 patients diagnosed with colorectal polyps (188 polyps) who underwent endoscopic surgery at our hospital between January 2022 and December 2022. Based on the surgical method employed, the patients were divided into 2 groups: EMR (68 cases, 97 polyps) and APC (64 cases, 91 polyps).

Whole-genome transcriptome and DNA methylation dynamics of pre-implantation embryos reveal progression of embryonic genome activation in buffaloes.

Background: During mammalian pre-implantation embryonic development (PED), the process of maternal-to-zygote transition (MZT) is well orchestrated by epigenetic modification and gene sequential expression, and it is related to the embryonic genome activation (EGA). During MZT, the embryos are sensitive to the environment and easy to arrest at this stage in vitro. However, the timing and regulation mechanism of EGA in buffaloes remain obscure.

White matter BOLD signals at 7 Tesla reveal visual field maps in optic radiation and vertical occipital fasciculus.

There is growing evidence that blood-oxygen-level-dependent (BOLD) activity in the white matter (WM) can be detected by functional magnetic resonance imaging (fMRI). However, the functional relevance and significance of WM BOLD signals remain controversial. Here we investigated whether 7T BOLD fMRI can reveal fine-scale functional organizations of a WM bundle.

Covalently connected core-shell NH-MIL-125@COFs-OH hybrid materials for visible-light-driven CO reduction.

Herein, the covalently connected core-shell metal-organic frameworks (MOFs)@covalent-organic frameworks (COFs) hybrid materials were successfully constructed by coating the stable COF-OH shell on the NH-MIL-125 core. The introduction of the NH-MIL-125 core endowed the hybrid materials with high Brunauer-Emmett-Teller (BET) surface area (S) and abundant unsaturated metal sites. And the coating of COF-OH shell endowed the hybrid materials outstanding physicochemical stability and visible-light response, and suitable band gaps.

Coordinated transcriptional and post-transcriptional epigenetic regulation during skeletal muscle development and growth in pigs.

Background: N6-methyladenosine (mA) and DNA 5-methylcytosine (5mC) methylation plays crucial roles in diverse biological processes, including skeletal muscle development and growth. Recent studies unveiled a potential link between these two systems, implicating the potential mechanism of coordinated transcriptional and post-transcriptional regulation in porcine prenatal myogenesis and postnatal skeletal muscle growth.

Methods: Immunofluorescence and co-IP assays were carried out between the 5mC writers and mA writers to investigate the molecular basis underneath.

A Deep Learning Framework for Start-End Frame Pair-Driven Motion Synthesis.

A start-end frame pair and a motion pattern-based motion synthesis scheme can provide more control to the synthesis process and produce content-various motion sequences. However, the data preparation for the motion training is intractable, and concatenating feature spaces of the start-end frame pair and the motion pattern lacks theoretical rationality in previous works. In this article, we propose a deep learning framework that completes automatic data preparation and learns the nonlinear mapping from start-end frame pairs to motion patterns.

Local Self-Expression Subspace Learning Network for Motion Capture Data.

Deep subspace learning is an important branch of self-supervised learning and has been a hot research topic in recent years, but current methods do not fully consider the individualities of temporal data and related tasks. In this paper, by transforming the individualities of motion capture data and segmentation task as the supervision, we propose the local self-expression subspace learning network. Specifically, considering the temporality of motion data, we use the temporal convolution module to extract temporal features.

Glomerular filtration rate calculation based on Ga-EDTA dynamic renal PET.

Positron emission tomography (PET) can accurately locate and quantify radioactivity over traditional single photon emission computed tomography (SPECT), encouraging its application in kidney function evaluation and glomerular filtration rate (GFR) measurement. Ga-ethylenediamine-tetraacetic acid (Ga-EDTA) is a novel PET tracer for renal scan but a mature GFR calculation method still pending establishment. Herein, we aim to investigate the imaging performance of Ga-EDTA dynamic PET in healthy C57BL/6 mice, establish quantitative methods to calculate GFR, and evaluate its feasibility in mice with kidney dysfunction.

Longitudinal physiological and transcriptomic analyses reveal the short term and long term response of Synechocystis sp. PCC6803 to cadmium stress.

Due to the bioaccumulation and non-biodegradability of cadmium, Cd can pose a serious threat to ecosystem even at low concentration. Microalgae is widely distributed photosynthetic organisms in nature, which is a promising heavy metal remover and an effective industrial sewage cleaner. However, there are few detailed reports on the short-term and long-term molecular mechanisms of microalgae under Cd stress.

Evaluation of Serum Levels of Copper and Zinc in Patients with Celiac Disease Seropositivity: Findings from the National Health and Nutrition Examination Survey.

Celiac disease is a multisystem immune based disorder, caused by an immune-mediated reaction to ingested gluten with increasing prevalence in the USA. Celiac disease can cause a wide variety of symptoms, including gastrointestinal symptoms (diarrhea, abdominal distention, or abdominal pain), which may affect absorption of many nutritional components. All patients with celiac disease should remain on a strict and lifelong gluten-free diet, which are often low in certain trace elements such as zinc.

Intensive care unit occupancy predictions in the COVID-19 pandemic based on age-structured modelling and differential flatness.

The COVID-19 pandemic confronts governments and their health systems with great challenges for disease management. In many countries, hospitalization and in particular ICU occupancy is the primary measure for policy makers to decide on possible non-pharmaceutical interventions. In this paper a combined methodology for the prediction of COVID-19 case numbers, case-specific hospitalization and ICU admission rates as well as hospital and ICU occupancies is proposed.

Upregulated WTAP expression in colorectal cancer correlates with tumor site and differentiation.

Few reports exist regarding the expression and function of Wilms' tumor 1-associated protein (WTAP) in colorectal cancer (CRC), and the evidence is controversial. Our analysis explored the expression of WTAP in CRC tissue, and analyzed its clinical and prognostic significance. WTAP expression was significantly higher in CRC tissue than in colorectal adenoma and normal colorectal tissue.

Longitudinal resting-state functional connectivity and regional brain atrophy-based biomarkers of preclinical cognitive impairment in healthy old adults.

Background: Intervention against age-related neurodegenerative diseases may be difficult once extensive structural and functional deteriorations have already occurred in the brain.

Aim: Investigating 6-year longitudinal changes and implications of regional brain atrophy and functional connectivity in the triple-network model as biomarkers of preclinical cognitive impairment in healthy aging.

Methods: We acquired longitudinal cognitive scores and magnetic resonance imaging (MRI) data from 74 healthy old adults.

assembly and transcriptome characterization: Novel insights into the mechanisms of primary ovarian cancer in .

The natural incidence of primary epithelial ovarian cancer (OVC) in adult female voles of some established strains of is relatively high. OVC has some pathological similarities to human epithelial OVC, therefore represents the latest and most valuable animal model for studying human OVC. The lack of available genetic information for limits the use of common immunological methods; thus, high‑throughput sequencing technologies have been used to reveal the mechanisms of primary OVC in .

Association of dietary magnesium intake with chronic constipation among US adults: Evidence from the National Health and Nutrition Examination Survey.

The association of dietary magnesium intake with chronic constipation has not been well-studied in general population. Therefore, the aim of this study was to examine whether increased intake of dietary magnesium is associated with the presence of chronic constipation. Data from the 2007-2010 National Health and Nutrition Examination Survey (NHANES) were used.

Surface modification and effects on tribology by laser texturing in AlO.

We investigate the surface modification by laser texturing and effects thereof on the tribological performance in . By detailed observation for microstructure evolution, it has been shown that there were three distinct modification morphologies by laser treatment: dense surface microfeatures, "coral" dendritic structures, and coarse grains. X-ray diffraction (XRD) results indicated that there was no formation of metastable phases due to low supercooling in solidification in the nanosecond laser regime.

Pose-Driven Realistic 2-D Motion Synthesis.

A realistic 2-D motion can be treated as a deforming process of an individual appearance texture driven by a sequence of human poses. In this article, we thereby propose to transform the 2-D motion synthesis into a pose conditioned realistic motion image generation task considering the promising performance of pose estimation technology and generative adversarial nets (GANs). However, the problem is that GAN is only suitable to do the region-aligned image translation task while motion synthesis involves a large number of spatial deformations.