Preoperative frailty in oesophageal cancer: postoperative outcomes and overall survival - meta-analysis and systematic review.

Purpose: To assess the prevalence of preoperative frailty in patients with oesophageal cancer and its impact on postoperative outcomes and overall survival.

Methods: A comprehensive computer-based search of the CNKI, Wanfang, VIP, CBM, PubMed, Embase, Cochrane Library, Web of Science and CINAHL databases was conducted for articles related to preoperative frailty in patients with oesophageal cancer. The search was carried out from the time of the construction of the database to 20 April 2024.

A case of large uterine cystic adenomyosis outside the uterus after laparoscopic myomectomy: a case report and literature review.

Background: Uterine cystic adenomyosis is a rare form of focal adenomyosis that is primarily located within the myometrium. In this case report, we present a unique case of adult uterine cystic adenomyosis found outside the uterus following laparoscopic myomectomy.

Case Presentation: The patient was a 36-year-old Chinese woman who had previously undergone laparoscopic surgery at our hospital to remove a 4 cm diameter diameter uterine fibroid six years prior.

Adipose ZFP36 protects against diet-induced obesity and insulin resistance.

Aims: Obesity, as a worldwide healthcare problem, has become more prevalent. ZFP36 is a well-known RNA-binding protein and involved in the posttranscriptional regulation of many physiological processes. Whether the adipose ZFP36 plays a role in obesity and insulin resistance remains unclear.

A review of cellulose and lignin contained rattan materials: Structure, properties, modifications, applications and perspectives.

Rattan is a multi-purpose plant resource in the tropical forest treasure house. With its good technological characteristics, it has become an excellent material for the preparation of industry. The original rattan is an important forest product second only to wood and bamboo.

The prognostic value of vascular endothelial growth factor in endometrial cancer: A protocol for systematic review and meta-analysis.

Background: A large number of studies have shown that high expression of vascular endothelial growth factor (VEGF) in cancer tissues is associated with poor prognosis of various cancers. However, this finding in endometrial cancer is controversial. Therefore, this meta-analysis aimed to explore the effects of VEGF on survival in patients with endometrial cancer.

Relationships among Helicobacter pylori seropositivity, the triglyceride-glucose index, and cardiovascular disease: a cohort study using the NHANES database.

Background: Helicobacter pylori (H. pylori), a widely prevalent pathogen that can be cured through relatively simple medical methods, is thought to be potentially associated with the risk of cardiovascular diseases (CVD), although controversy remains. Currently, it is unclear whether the triglyceride-glucose index (TGI), a classic indicator of insulin resistance, influences the relationship between H.

Expression and prognostic impact of hypoxia- and immune escape-related genes in triple-negative breast cancer: A comprehensive analysis.

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks effective therapeutic options. Hypoxia and immune escape are critical factors that contribute to the progression of and resistance to therapy in patients with TNBC. Nevertheless, few studies have comprehensively analyzed hypoxia and immune escape in patients with TNBC.

The role of CD47 in immune escape of colon cancer and its correlation with heterogeneity of tumor immune microenvironment.

Background: Cluster of differentiation 47 (CD47), a transmembrane protein, plays a critical role in regulating cellular functions and maintaining immune homeostasis. Its expression has been shown to influence cancer prognosis. In this study, we investigated the role of CD47 in tumor progression in colon adenocarcinoma (COAD) and evaluated its potential as a target for immunotherapy.

TRPML1 acts as a predisposing factor in lymphedema development by regulating the subcellular localization of aquaporin-3, -5.

An imbalance in lymphatic fluid, whether it is caused by generation, transport, outflow, or dysfunctional vessels, can lead to lymphedema; however, the exact pathogenesis of this disease remains unclear. To explore the mechanism, we focused on the association among TRPML1, aquaporin-3 (AQP3), and aquaporin-5 (AQP5) in human lymphatic endothelial cells (HLECs). We explored the role of TRPML1 in altering the permeability of HLECs in lymphedema.

Case Report: Zero-contrast balloon pulmonary angioplasty guided by real-time fusion of CT angiography with x-ray fluoroscopy.

Background: Allergy to iodine contrast agents has long been a contraindication for balloon pulmonary angioplasty (BPA). We report the successful zero-contrast BPA procedure of a patient with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and severe iodine allergy using real-time fusion of computed tomography angiography (CTA) with x-ray fluoroscopy.

Case Presentation: A 62-year-old woman with CTEPH who developed a severe allergic reaction after the first BPA procedure.

An Fe-doped Ni-based oxalate framework with a favorable electronic structure for electrocatalytic water and urea oxidation.

An Fe-doped Ni-based oxalate framework, synthesized a facile co-precipitation method, is applied as an excellent bi-functional electrocatalyst for water and urea oxidation reactions. The obtained framework achieved a large current density of 100 mA cm at 1.497 V and 1.

High Mechanical Cellulose-Based Aerogel Induced by Fe at Ambient Temperature and Pressure.

Nanocellulose aerogels are usually produced by methods such as freeze-drying or critical point drying, which have the disadvantages of high equipment requirements and high energy consumption. In this study, the Fe-containing ethanol bath was employed to dissolve and replace ice crystals in the prefrozen precursors of cellulose-based aerogels. The method achieved both solvent substitution and metal ion complexation and successfully prepared nanocellulose aerogels with a total solid concentration of 2.

Molecular mechanisms of lipid droplets-mitochondria coupling in obesity and metabolic syndrome: insights and pharmacological implications.

Abnormal lipid accumulation is a fundamental contributor to obesity and metabolic disorders. Lipid droplets (LDs) and mitochondria (MT) serve as organelle chaperones in lipid metabolism and energy balance. LDs play a crucial role in lipid storage and mobilization, working in conjunction with MT to regulate lipid metabolism within the liver, brown adipose tissue, and skeletal muscle, thereby maintaining metabolic homeostasis.

[Research progresses of Qa-1 restricted CD8 regulatory T cells in the pathogenesis of infectious diseases].

The Qa-1 in mice is homologous to human leukocyte antigen E(HLA-E), and both of them belong to the non-classical major histocompatibility complex I b(MHC-I b) molecules. Qa-1 is capable of presenting self or exogenous antigen peptides to interact with two distinct receptors, namely T cell receptor (TCR) and natural killer cell group 2 member A (or C) (NKG2A/C), thus playing an important role in immune response and regulation. Qa-1-restricted regulatory CD8 T cell (CD8 Treg) is one of the most studied CD8 Treg subgroups, which can maintain immune homeostasis and autoimmune tolerance by exerting immunosuppressive effects.

Experimental demonstration of improved reference-frame-independent quantum key distribution over 175km.

Reference-frame-independent (RFI) quantum key distribution (QKD) presents promising advantages, especially for mobile-platform-based implementations, as it eliminates the need for active reference frame calibration. While RFI-QKD has been explored in various studies, limitations in key rate and distance persist due to finite data collection. In this study, we experimentally demonstrate an improved RFI-QKD protocol proposed by Zhu et al.

The protective effect of rutin on sciatic nerve injury in acrylamide-exposed rats and its mechanisms.

Rutin (Rut) is a flavonoid with pharmacological activities such as anti-inflammatory and antioxidant. Acrylamide (ACR) is a toxic substance widely found in human life that can induce neurotoxicity. Some studies have confirmed that neurotoxicity caused by ACR induces myelin damage, which in turn causes neurological dysfunction.

Dietary Flavonoid Intake and Risk of Mild Cognitive Impairment in the Elderly: A Case-Control Study.

Background: This study investigates the association between dietary flavonoid intake and the incidence of mild cognitive impairment (MCI) through a matched case-control design.

Methods: Dietary intake was assessed using a food frequency questionnaire, comparing the intake of flavonoids between individuals with MCI and those with normal cognitive function. Logistic regression analysis was employed to evaluate the correlation between dietary flavonoid intake and the risk of MCI.

Preferences of Cancer Survivors for Follow-Up Care: A Systematic Review of Discrete Choice Experiments.

Background And Objective: Cancer survivors frequently encounter multiple challenges, including physical, psychological, social, emotional, and financial difficulties. These challenges significantly impact their quality of life and recovery process. This systematic review intends to delineate and assess the evidence gathered from discrete choice experiments, aiming to unravel the preferences of cancer survivors towards their follow-up care.