Correction: Zhang et al. Hepatitis B Virus X Protein (HBx) Suppresses Transcription Factor EB (TFEB) Resulting in Stabilization of Integrin Beta 1 (ITGB1) in Hepatocellular Carcinoma Cells. 2021, , 1181.

In the original publication [...

Imaging and Clinical Features of Primary Thoracic Lymphangioma.

Background: Primary thoracic lymphangioma is a rare disease. Most of the previous studies are comprised of individual case reports, with a very limited number of patients included.

Objective: This study aims to investigate the chest computed tomography (CT) imaging features and clinical manifestations of thoracic lymphangioma, thereby enhancing our understanding of the condition.

Termination-acidity tailoring of molybdenum carbides for alkaline hydrogen evolution reaction.

Transition-metal carbides have been advocated as the promising alternatives to noble-metal platinum-based catalysts in electrocatalytic hydrogen evolution reaction over half a century. However, the effectiveness of transition-metal carbides catalyzing hydrogen evolution in high-pH electrolyte is severely compromised due to the lowered proton activity and intractable alkaline-leaching issue of transition-metal centers. Herein, on the basis of validation of molybdenum-carbide model-catalyst system by taking advantage of surface science techniques, MoC micro-size spheres terminated by Al doped MoO layer exhibit a notable performance of alkaline hydrogen evolution with a near-zero onset-potential, a low overpotential (40 mV) at a typical current density of 10 mA/cm, and a small Tafel slope (45 mV/dec), as well as a long-term stability for continuous hydrogen production over 200 h.

Application of autophagy in mesenchymal stem cells.

In this editorial, we have taken an in-depth look at the article published by Wan . The study showed that preconditioning mesenchymal stem cells (MSCs) protected them against programmed cell death, and increased their survival rate and therapeutic potential. Autophagy, a type of programmed cell death, is a major intracellular degradation and recycling pathway that is crucial for maintaining cellular homeostasis, self-renewal, and pluripotency.

Structural-functional connectivity decoupling in multiscale brain networks in Parkinson's disease.

Background: Parkinson's disease (PD) is a progressive neurodegenerative disease associated with functional and structural alterations beyond the nigrostriatal dopamine projection. However, the structural-functional (SC-FC) coupling changes in combination with subcortical regions at the network level are rarely investigated in PD.

Methods: SC-FC coupling networks were systematically constructed using the structural connectivity obtained by diffusion tensor imaging and the functional connectivity obtained by resting-state functional magnetic resonance imaging in 53 PD and 72 age- and sex-matched healthy controls (HCs).

YAP/TAZ as master regulators in liver regeneration and disease: insights into mechanisms and therapeutic targets.

Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are key downstream effectors of the Hippo pathway that regulate organ size, tissue homeostasis, and cancer development. YAP/TAZ play crucial regulatory roles in organ growth, cell proliferation, cell renewal, and regeneration. Mechanistically, YAP/TAZ influence the occurrence and progression of liver regeneration (LR) through various signaling pathways, including Notch, Wnt/β-catenin, TGF-β/Smad.

Mechanism of Endometrial Receptivity Affected by Fibroids.

Fibroids are the most common benign tumors of the female reproductive system. Most patients with fibroids are asymptomatic, but the presence of fibroids can still cause some abnormal clinical symptoms, such as increased menstrual volume, abnormal uterine bleeding, pelvic pain, urinary tract and gastrointestinal tract compression symptoms, etc. The impact of fibroids on pregnancy is worth discussing.

Local CpG- siRNA treatment improves antitumor effects of immune checkpoint inhibitors.

Immune checkpoint blockade (ICB) therapy has significantly benefited patients with several types of solid tumors and some lymphomas. However, many of the treated patients do not have a durable clinical response. It has been demonstrated that rescuing exhausted CD8 T cells is required for ICB-mediated antitumor effects.

The enhancement mechanisms of chondroitin sulfate on α-amylase activity: Exploring the interaction using in vitro and in silico studies.

Glycosaminoglycans (GAG) are bioactive polysaccharide rich in -SO- and -COO- groups, also known as acidic mucopolysaccharides. In this study, the feasibility of three structurally distinct forms of chondroitin sulfate (CS-A, CS-C, and CS-D) from the GAG family was explored as a potential strategy to enhance industrial α-amylase activity. All three CSs were found to increase α-amylase activity to varying degrees, with CS-D showing the most significant increase, exceeding 78 %.

Calnexin interacts with B-cell receptor-associated protein 31 (Bap31) to mediate coelomocyte phagocytosis and Vibrio splendidus clearance in Apostichopus japonicus.

Calnexin serves as a lectin chaperone located on the endoplasmic reticulum membrane and functions in glycoprotein folding and synthesis quality control, as well as in Ca storage. Calnexin is extensively documented to participate in host immunity in the endoplasmic reticulum. However, the functions and fundamental mechanisms of calnexin in the invertebrate innate defence remain largely unknown.

A high entropy metallic-high entropy nonmetallic community as a high performance electrocatalyst for the oxygen evolution reaction and oxygen reduction reaction.

The multi-element synergism in high-entropy materials (HEMs) provides great opportunities as multi-functional catalysts or for the promotion of tandem reactions. Herein, a strategy that utilizes a high entropy precursor is proposed to realize the formation of a unique high entropy metallic-high entropy non-metallic community (HEM-HENMC). Aminotriazole acts as a "bonding agent" for the high entropy precursor, and not only binds the five metals Cr, Mn, Fe, Co and Ni together, but also introduces nitrogen and carbon .

Targeting TSPEAR-AS2 suppresses tumor growth and interferon signaling in esophageal cancer.

Dysregulation of long non-coding RNAs (lncRNAs) and interferon signaling contributes to tumorigenesis and progression; however, their crosstalk in tumor biology remains poorly understood. Here, we showed that TSPEAR-AS2, an lncRNA mediated by METTL1, activates the interferon signaling pathway in esophageal cancer (ESCA). Clinically, we conducted a pan-cancer investigation and identified TSPEAR-AS2 as a novel ESCA-related lncRNA that predicts a worse patient prognosis.

The Potential of Defatted Yellow Mealworm () Meal as an Alternative Protein Source for Juvenile Chinese Mitten Crab ().

This study was aimed to investigate the effects of replacing dietary fish meal (FM) with defatted yellow mealworm () meal (DYM) on growth performance, intestinal health, serum immune, and antioxidant indexes of juvenile Chinese mitten crab (). Four hundred juvenile Chinese mitten crabs (4.94 ± 0.

Impact of COVID-19 on the Prevalence and Drug Resistance of Bacteria Isolated From Bacterial Meningitis Cerebrospinal Fluid in Shandong Province: A Multicenter Retrospective Study.

Our objective was to evaluate the ramifications of the 2019 coronavirus disease (COVID-19) pandemic on the microbial profile and antimicrobial resistance patterns of bacteria isolated from cerebrospinal fluid (CSF) specimens of patients with bacterial meningitis. We conducted a retrospective analysis of laboratory results and clinical records about positive CSF cultures reported by the SPARSS network from 2017 to 2023. The study covered three distinct periods: January 2017 to December 2019 (before the COVID-19 pandemic), January 2020 to December 2022 (during the COVID-19 pandemic), and January 2023 to December 2023 (after the COVID-19 pandemic), with a total of 5793 CSF isolates collected.

Self-Templated 3D Sulfide-Based Solid Composite Electrolyte for Solid-State Sodium Metal Batteries.

Rechargeable solid-state sodium metal batteries (SSMBs) experience growing attention owing to the increased energy density (vs Na-ion batteries) and cost-effective materials. Inorganic sulfide-based Na-ion conductors also possess significant potential as promising solid electrolytes (SEs) in SSMBs. Nevertheless, due to the highly reactive Na metal, poor interface compatibility is the biggest obstacle for inorganic sulfide solid electrolytes such as NaSbS to achieve high performance in SSMBs.

Hemorrhages and risk factors in patients undergoing thromboprophylaxis in a respiratory critical care unit: a secondary data analysis of a cohort study.

Objective: To verify whether the bleeding risk assessment guidelines from the 9th American College of Chest Physicians (ACCP) are prognostic for respiratory intensive care unit (RICU) patients and to explore risk factors for hemorrhages, we conducted a secondary data analysis based on our previously published cohort study of venous thromboembolism.

Patients And Methods: We performed a secondary data analysis on the single-center prospective cohort from our previous study. Patients admitted to the RICU at Beijing Chao-Yang Hospital from August 1, 2014 to December 31, 2020 were included and followed up until discharge.

The first child with mixed invasive pulmonary and infection: a case report and literature review.

Purpose: Coinfections or consecutive infections of and are exceedingly uncommon in children, we report the case to offer the valuable experience for colleagues facing similar situations.

Case Report: This report documents the first recorded case of successful treatment for pulmonary mixed infection in a diabetic girl. Initially, the patient underwent treatment based on voriconazole, but the infection continued to deteriorate.