Anisotropic Plasmon Resonance in TiCT MXene Enables Site-Selective Plasmonic Catalysis.

The ever-growing interest in MXenes has been driven by their distinct electrical, thermal, mechanical, and optical properties. In this context, further revealing their physicochemical attributes remains the key frontier of MXene materials. Herein, we report the anisotropic localized surface plasmon resonance (LSPR) features in TiCT MXene as well as site-selective photocatalysis enabled by the photophysical anisotropy.

Integrating bioinformatics and machine learning to unravel shared mechanisms and biomarkers in chronic obstructive pulmonary disease and type 2 diabetes.

Background: Chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are on the rise. While there is evidence of a link between the two diseases, the pathophysiological mechanisms they share are not fully understood.

Methods: In this study, the co-expressed genes of COPD and T2DM in Gene Expression Omnibus database were identified by bioinformatics method, and the functional enrichment analysis was performed.

Monitoring long-term cardiac activity with contactless radio frequency signals.

Cardiovascular diseases claim over 10 million lives annually, highlighting the critical need for long-term monitoring and early detection of cardiac abnormalities. Existing techniques like electrocardiograms (ECG) and Holter are accurate but suffer from discomfort caused by body-attached electrodes. While wearable devices using photoplethysmography offer more convenience, they sacrifice accuracy and are susceptible to environmental interference.

Mucosal Hub Bacteria as Potential Targets for Improving High-Fat Diet-Related Intestinal Barrier Injury.

Intestinal barrier injury contributes to multiple diseases such as obesity and diabetes, whereas no treatment options are available. Due to close interactions between mucosal microbiome and intestinal barrier, we evaluated the potential of mucosal bacteria in providing targets for high-fat diet (HFD)-related intestinal barrier injury. Whole-genome metagenomics was used to evaluate mucosal microbiome, while intestinal barrier injury was estimated using serum LPS, FITC-dextran intensity, and ZO-1 protein.

Characterization of a Putative Lysin from Enterococcus faecalis Phage IME-EFm1 and Determination of its Protective Efficacy in Mice.

The rising tide of bacterial drug resistance has sparked renewed interest in bacteriophages, the natural predators of bacteria. Our study highlights IME-EFm1, a Caudoviricetes bacteriophage specifically targeting Enterococcus faecium. Through our investigations, we identified that the gene IME-EFm1-ORF24 encodes an amidase, referred to as gp24, with promising lytic capabilities.

Sensitive and portable intelligent detection platform construction and dietary risk assessment of procymidone in Chinese leek, cowpea and celery.

Procymidone (PRM), a widely used amide-type fungicide in vegetables, poses potential health risks due to its high detection rate. This study introduces a pretreatment device and an intelligent quantification method for PRM in Chinese leek, cowpea, and celery using a lateral flow immunoassay (LFIA) integrated with a smartphone. The whole pretreatment and detection process can be achieved within 21 min.

Elucidating the influence of volatile compounds on aroma profiles across peach ( L.) cultivars and offspring exhibiting diverse flesh colors.

Yellow- and white-fleshed peach fruits are favored for their diverse flesh colors. While carotenoid accumulation primarily dictates flesh color differences, the influence of volatile compounds on their aromas remains largely unexplored. Here, multiple analytical methods including odor importance assessment, hierarchical clustering, and aroma characterization analysis were employed to investigate volatile compositions and aroma characteristics of the two types of peach, as well as the offspring with identical parentage.

Mormyroidea-inspired electronic skin for active non-contact three-dimensional tracking and sensing.

The capacity to discern and locate positions in three-dimensional space is crucial for human-machine interfaces and robotic perception. However, current soft electronics can only obtain two-dimensional spatial locations through physical contact. In this study, we report a non-contact position targeting concept enabled by transparent and thin soft electronic skin (E-skin) with three-dimensional sensing capabilities.

Rapid Dual-Gene Detection of Burkholderia gladioli and Subspecies Cocovenenans in Fresh Noodles and Tremella Using CRISPR-Cas12a/Cas13a.

Background: Burkholderia gladioli pv. cocovenenans is a notable foodborne pathogen that poses a significant risk to food safety. Contaminated food requires distinct classification and treatment procedures for non-pathogenic B.

Analysis of risk factors for carotid artery plaque in asymptomatic adults.

Objective: This study aimed to investigate the risk factors affecting the presence of carotid plaque in asymptomatic adults.

Methods: Asymptomatic adults (age > 40 years, no symptoms of cardiovascular and cerebrovascular diseases) undergoing routine health examinations from physical examination department were included in this study. Carotid plaque was measured by Resona 7OB and Resona 8EXP color Doppler ultrasound and L9-3U and L4-5WU probes.

Application of target scanning combined with three-dimensional reconstruction in the diagnosis of early-stage lung adenocarcinoma.

This study aimed to assess the diagnostic value of target scanning combined with three-dimensional reconstruction in early-stage lung adenocarcinoma. A retrospective analysis was conducted on 2017 patients with pathologically confirmed early-stage lung adenocarcinoma who underwent thoracoscopic lobectomy at the First Affiliated Hospital of Anhui Medical University from September 2018 to May 2023. These patients were initially diagnosed using conventional spiral CT scanning, and the study explored the application of target scanning combined with three-dimensional reconstruction in the diagnosis of early-stage lung adenocarcinoma.

Study of Time-Resolved Dynamics in Turbid Medium Using a Single-Cavity Dual-Comb Laser.

In measuring cerebral blood flow (CBF) noninvasively using optical techniques, diffusing-wave spectroscopy is often combined with near-infrared spectroscopy to obtain a reliable blood flow index. Measuring the blood flow index at a determined depth remains the ultimate goal. In this study, we present a simple approach using dual-comb lasers where we simultaneously measure the absorption coefficient (μ), the reduced scattering coefficient (μ ), and dynamic properties.

Easily Applicable Superhydrophobic Composite Coating with Improved Corrosion Resistance and Delayed Icing Properties.

Mitigating the adverse effects of corrosion failure and low-temperature icing on aluminum (Al) alloy materials poses significant research challenges. The facile fabrication of bioinspired superhydrophobic materials offers a promising solution to the issues of corrosion and icing. In this study, we utilized laboratory-collected candle soot (CS), hydrophobic fumed SiO, and epoxy resin (EP) to create a HF-SiO@CS@EP superhydrophobic coating on Al alloy surfaces using a spray-coating technique.

A model integrating attention mechanism and generative adversarial network for image style transfer.

Image style transfer is an important way to combine different styles and contents to generate new images, which plays an important role in computer vision tasks such as image reconstruction and image texture synthesis. In style transfer tasks, there are often long-distance dependencies between pixels of different styles and contents, and existing neural network-based work cannot handle this problem well. This paper constructs a generation model for style transfer based on the cycle-consistent network and the attention mechanism.

TMEM100 acts as a TAK1 receptor that prevents pathological cardiac hypertrophy progression.

Pathological cardiac hypertrophy is the primary cause of heart failure, yet its underlying mechanisms remain incompletely understood. Transmembrane protein 100 (TMEM100) plays a role in various disorders, such as nervous system disease, pain and tumorigenesis, but its function in pathological cardiac hypertrophy is still unknown. In this study, we observed that TMEM100 is upregulated in cardiac hypertrophy.

A buffering PVDF-HFP-based gel polymer electrolyte for stable and flexible lithium batteries.

Flexible lithium batteries (FLBs) are highly regarded as potential candidates for next-generation batteries due to their versatility in various applications. However, the main focus in the development of FLBs lies in addressing mechanical challenges such as crack propagation under conditions of flexibility and stretchability. Herein, this work presents a novel design of a gel polymer electrolyte (GPE112) film prepared by solution-casting methods.

Precisely Designed Morphology and Surface Chemical Structure of Fe-N-C Electrocatalysts for Enhanced Oxygen Reaction Reduction Activity.

Fe-N-C materials have been regarded as one of the potential candidates to replace traditional noble-metal-based electrocatalysts for the oxygen reduction reaction (ORR). It is believed that the structure of carbon support in Fe-N-C materials plays an essential role in highly efficient ORR. However, precisely designing the morphology and surface chemical structure of carbon support remains a challenge.

Predicting lncRNA-Disease Associations Based on a Dual-Path Feature Extraction Network with Multiple Sources of Information Integration.

Identifying the associations between long noncoding RNAs (lncRNAs) and disease is critical for disease prevention, diagnosis and treatment. However, conducting wet experiments to discover these associations is time-consuming and costly. Therefore, computational modeling for predicting lncRNA-disease associations (LDAs) has become an important alternative.

RELA-mediated upregulation of LINC03047 promotes ferroptosis in silica-induced pulmonary fibrosis via SLC39A14.

Long non-coding RNAs play a key role in silicosis, a fatal fibrotic lung disease, and there is an urgent need to develop new treatment targets. Long intergenic non-protein-coding RNA 3047 (LINC03047) is associated with cancer, but its role and mechanism in the progression of silicosis require further elucidation. This study investigated the function of LINC03047 in the epithelial-mesenchymal transition (EMT) during silicosis progression.