Fingerprint-Inspired Strain Sensor with Balanced Sensitivity and Strain Range Using Laser-Induced Graphene.

Sensitivity and strain range are two mutually exclusive features of strain sensors, where a significant improvement in flexibility is usually accompanied by a reduction in sensitivity. The skin of a human fingertip, due to its undulating fingerprint pattern, can easily detect environmental signals and enhances sensitivity without losing elasticity. Inspired by this characteristic, laser-induced graphene (LIG) with a fingerprint structure is prepared in one step on a polyimide (PI) film and transferred into an Ecoflex substrate to assemble resistive strain sensors.

Helix B Surface Peptide Protects Cardiomyocytes From Hypoxia/Reoxygenation-induced Autophagy Through the PI3K/Akt Pathway.

Background: Helix B surface peptide (HBSP) is a newly discovered tissue-protective erythropoietin derivative that provides benefits after myocardial ischemia/reperfusion. This study explores the cardioprotective effects of HBSP in myocardial cells in response to hypoxia/reoxygenation injury and its potential mechanism.

Methods: In this study, rat ventricular (H9c2) cell cultures were established and pretreated with HBSP.

Erythropoietin helix B surface peptide modulates miR-21/Atg12 axis to alleviates cardiomyocyte hypoxia-reoxygenation injury.

Background: The erythropoietin helix B surface peptide (HBSP) has been shown to have neuroprotective and repair-damaging myocardium effects similar to erythropoietin (EPO). However, the protective mechanism of HBSP on cardiomyocyte hypoxia-reoxygenation (H/R) injury is not clear.

Methods: H9C2 cells were pretreated with HBSP and subjected to hypoxia/reoxygenation (H/R), changes in cell function, autophagy and apoptosis were assessed, respectively.