[Testicular histology does not affect the clinical outcomes of ICSI in men with non-obstructive azoospermia].

Objective: To investigate whether testicular histology influences the clinical outcomes of intracytoplasmic sperm injection (ICSI) in men with non-obstructive azoospermia (NOA).

Methods: We retrospectively analyzed the clinical data about 73 cases of NOA undergoing ICSI, including 105 ICSI cycles and 79 embryo transfer cycles. The infertility of the patients was attributed to male factors only or both male and female tube factors and the females' age was ≤38 years.

[Safety and efficacy of China-made sildenafil citrate in the treatment of erectile dysfunction].

Objective: To evaluate the safety, efficacy and tolerability of China-made sildenafil citrate (Jinge) in the treatment of ED.

Methods: We conducted a multi-center, randomized, double-blind and placebo-controlled clinical trial among 222 ED patients in five urological or andrological clinics of China. The patients were randomly assigned to receive sildenafil citrate (SC, n = 111) or placebo (n = 111) for 8 weeks.

[Effect of Y chromosomal length variation on male reproductive dysfunction].

Objective: To investigate the effects of big and bit Y chromosome configurations on male fertility and to evaluate the relevant clinical significance.

Methods: The relevant cases were divided into A and B groups. Group A included male infertile cases.

Help-seeking behavior for erectile dysfunction: a clinic-based survey in China.

The behavior of Chinese patients seeking help for erectile dysfunction (ED) has not been described in detail. This was an observational study conducted using an outpatient clinic-based questionnaire survey of ED patients. From 2008 to 2009, physicians in 10 medical centers in China enrolled 2693 men (aged 25-70 years) diagnosed with ED.

[Testicular sperm cryopreservation for male fertility preservation].

Objective: To investigate the effectiveness of testicular sperm cryopreservation in male fertility preservation by evaluating the clinical outcome of ICSI cycles with frozen-thawed testicular sperm for azoospermia patients.

Methods: We retrospectively analyzed 96 samples of cryopreserved testicular sperm obtained by testicular biopsy, vasovasostomy (V-V), vasoepididymostomy (V-E) , of which 55 were subjected to 60 ICSI cycles with frozen-thawed testicular sperm. We evaluated the rates of sperm recovery, fertilization, cleavage, transferable and good-quality embryos, clinical pregnancy, pregnancy outcome, and health of the newborns.

[Sex therapy is effective for erectile dysfunction].

Objective: To evaluate the sex therapy for erectile dysfunction (ED).

Methods: We recommended the sex therapy to ED patients and their partners (11 couples in all) in the outpatient department. Of the total number of volunteers, 2 males were accompanied by ejaculation disorder, another 2 with hyposexuality, and 1 female had vaginismus.

[Aildenafil citrate: a new potent and highly selective phosphodiesterase type 5 inhibitor for the treatment of erectile dysfunction].

Objective: To evaluate the efficacy and safety of aildenafil citrate, an oral phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction.

Methods: Integrated analyses were made of 8-week, randomized, double-blind, placebo-controlled phase 2 clinical trials involving 250 men with mild-to-severe erectile dysfunction of various etiologies who received aildenafil citrate 30 or 60 mg (n = 167) or placebo (n = 83).

Results: The statistic results of International Index of Erectile Function, Patient Sexual Encounter Profile (SEP) diaries and Global Assessment Question (GAQ) were significantly higher in the aildenafil citrate patients than in the placebo controls.

[Factors affecting clinical application of sex therapy for erectile dysfunction].

Objective: To discuss the factors that affect the clinical application of sex therapy for erectile dysfunction (ED).

Methods: Urological researchers recommended free sex therapy to ED patients and their partners in the outpatient department and studied the factors affecting the patients of Medicaid their partnersology, acceptance of sex therapy by interview and observation.

Results: Many patients refused sex therapy.

[Diagnosis and differential diagnosis value of ultrasound in epididymal mass].

Objective: To elevate the diagnosis and differential diagnosis levels of epididymal mass by sonography.

Methods: This was a retrospective study of 179 cases of epididymal mass treated by surgery in our hospital between 1990 and 2005. The analysis was focused on pathological and sonographic features.

[The value of dynamic color duplex scanning in the diagnosis of vascular erectile dysfunction].

Objective: To evaluate deep penile arterial flow after an intracavernosal injection with prostaglandin E1 in patients with erectile dysfunction (ED).

Methods: 527 patients with ED were evaluated using Color Doppler Ultrasonography. Diagnostic tests were undertaken after an intracavernosal injection with 20 microg prostaglandin El.

[Effects of sildenafil on erectile dysfunction in the aged men with diabetes].

Objective: To evaluate the efficacy and safety of sildenafil on erectile dysfunction in the aged men with diabetes.

Methods: One hundred and ten patients aged 55 years old above with type I or II diabetes and a minimum 3-month history of ED were studied. Patients were instructed to take one dose of their treatment orally at any time before anticipated sexual activity.

[Effects of food and alcohol on the pharmacokinetics of vardenafil].

There is a close relationship between sexual activity and meals or alcohol consumption. It is of great clinical significance for clinicians to understand the effects of food and alcohol on the pharmacokinetics of phosphodiesterase-5 inhibitor vardenafil so as to give correct instructions to patients. Although a high-fat ( > 55% fat calories) meal modestly reduces C(max) by 18% and prolongs t(max) of vardenafil by approximately 1 hour, no significant effects of a typical moderate-fat meal (30% fat calories) on vardenafil pharmacokinetics were observed in a study carried out in 25 healthy adult males.

[Long-term efficacy of TRUS-guided transperineal needle aspiration and irrigation on persistent hematospermia].

Objective: To evaluate the long-term efficacy of transrectal ultrasonography (TRUS)-guided transperineal needle aspiration and irrigation for persistent hematospermia.

Methods: Included in the study were 12 patients with persistent hematospermia, aged (36.4 +/- 10.

[Etiology and management of persistent hematospermia: a pilot study].

Objectives: To study the etiology of persistent hematospermia and to evaluate the efficacy of transrectal ultrasonography (TRUS)-guided transperineal needle aspiration and irrigation for diagnosis and treatment of persistent hematospermia.

Methods: Twelve patients were included in the study, with a mean age of (36.4 +/- 10.

[Physicians' knowledge and attitude to erectile dysfunction].

Objectives: The physicians knowledge and attitude to erectile dysfunction (ED) is very important to the diagnosis and management of this disease. We investigated the physicians and practitioners knowledge of ED, attitude to ED, and if they actively find the underlying ED patients.

Methods: Three hundreds and one physicians and practitioners in Beijing completed a questionnaire.