Publications by authors named "Zhan-Qiang Wang"
Article Synopsis
- A novel bacterium called strain ZHW00191 was isolated from human feces and characterized, showing it is a Gram-positive, non-motile, obligate anaerobe.
- It thrives at temperatures of 25-45°C, with an optimum around 37-42°C, and can grow in a pH range of 5.5-10.0, preferring pH 6.5-7.0, while not tolerating salt well.
- Genetic analysis and comparison with related strains indicate that ZHW00191 represents a new genus and species, proposing the name for classification within microbiology.
Background: The mechanism of post-stroke cognitive impairment (PSCI) has not been explained. We aimed to investigate whether miR-let-7i participates in the PSCI and illuminates its underlying role in oxygen-glucose deprivation (OGD)-induced cell apoptosis.
Methods: Blood samples from 36 subjects with PSCI and 38 with post-stroke cognitive normality (Non-PSCI) were collected to evaluate the differential expression of miR-let-7 family members, using qRT-PCT analysis.
It has been well established that the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) opener, diazoxide, has protective effects on the heart and brain following ischemia/reperfusion injury. However, the mechanism of the neuroprotective effects of diazoxide remains unclear. This study highlights the anti-apoptotic effects of the drug, which are mediated by specific regulation of apoptosis-inducing factor (AIF) in the process of oxygen and glucose deprivation (OGD)-induced apoptosis in SH-SY5Y cells.
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