Modulating Treg cell activity in prostate cancer via chitosan nanoparticles loaded with si-BATF/PRDM1.

Prostate cancer is a significant health issue, with regulatory T (Treg) cells playing a crucial role in its progression. This study explores the potential of chitosan-modified magnetic nanoparticles loaded with si-BATF/PRDM1 to target Treg cell activity in impeding prostate cancer development. By understanding the function of BATF and PRDM1 in Treg cells, the research demonstrates their central involvement in prostate cancer progression.

Microsatellite analysis of genetic variation and population genetic differentiation in autotetraploid and diploid rice.

Genetic diversity and population genetic structure of autotetraploid and diploid populations of rice collected from Chengdu Institute of Biology, Chinese Academy of Sciences, were studied based on 36 microsatellite loci. Among 50 varieties, a moderate to high level of genetic diversity was observed at the population level, with the number of alleles per locus (Ae) ranging from 2 to 6 (mean 3.028) and polymorphism information content ranging from 0.