[Preparation and identification of PON2 monoclonal antibodies.].

Aim: To prepare and characterize the mouse monoclonal antibodies against human PON2 (paraoxonase 2).

Methods: A fragment of human PON2 gene of low homology with mice but of strong hydrophilicity and immunogenicity was selected for recombinant expression. Mice were immunized with the purified HIS fusion protein 3 times.