A nematic liquid crystal confined to the surface of a sphere exhibits topological defects of total charge +2 due to the topological constraint. In equilibrium, the nematic field forms four +1/2 defects, located at the corners of a regular tetrahedron inscribed within the sphere, since this minimizes the Frank elastic energy. If additionally the individual nematogens exhibit self-driven directional motion, the resulting active system creates large-scale flow that drives it out of equilibrium.
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