Publications by authors named "Zhan-Chao Ye"

Background: Liver diseases have been bound to environmental factors, inclusive of air pollution. The exposure of workers to petrochemicals counts as a possible cause of Liver diseases, whereas results are inconsistent with the previous studies. In this study, a meta-analysis is conducted to assess the pooled risk.

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Objective: To evaluate the effect of maxillary sinus elevation with gene-enhanced tissue engineering bone in dogs.

Methods: bone marrow stromal cells (BMSC) derived from dog marrow were cultured, and transduced with the adenovirus carrying bone morphogenetic protein-2 (BMP-2) gene (AdBMP-2), the adenovirus carrying green fluorescent protein (GFP) gene (AdGFP) in vitro. The bone formation ability of gene modified BMSC with scaffold was examined in nude mice and in elevated maxillary sinus of dog.

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Purpose: To evaluate the clinical effectiveness and feasibility of immediate implant-supported mandibular overdentures retained by conical crowns.

Methods: In this study, 10 patients with edentulous mandible were included. They were restored by traditional complete denture before operation.

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Objective: To evaluate the effect of tissue engineering bone in maxillary sinus lifting.

Methods: The marrow stromal stem cells of dog were cultured in DMEM containing 100 m1/L fetal bovine serum and induced to differentiate to osteoblasts, which were then inoculated together with Bio-Oss for 5 days. Sixteen dog's bilateral maxillary sinus were elevated.

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Purpose: To evaluate the effect of radiation and osteogenic growth peptide(OGP) on the bone density adjacent to the implants.

Methods: 24 rabbits underwent 48 implants placed in the tibia, then the rabbits were divided into one control group and two experimental groups randomly. Rabbits in one of the experimental groups were injected with OGP Sol, rabbits in the other groups were injected with normal saline; Then rabbits in the two experimental groups received radiation after the implant wound healed.

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Purpose: To evaluate the effectiveness of the tissue engineered bone substitute loaded with periosteal-derived osteoblasts (POBs) transfected by adenovirus mediated human bone morphogenetic protein-2 gene (Ad-hBMP-2) in the repair of rabbit mandibular central fissures.

Methods: 45 rabbits with the soft tissue in the mandibular central fissures removed were randomly divided into 5 groups, group I: Ad-hBMP-2 transfected POBs/bioglass group (n=10); group II: adenovirus mediated enhanced green fluorescent protein (Ad-EGFP) gene transfected POBs/bioglass group (n=10); group III: untransfected POBs/bioglass group (n=10); group IV: single bioglass group (n=10); group V: control group (n=5). The above bone substitutes were implanted in the rabbit mandibular central fissures respectively except group V.

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