Publications by authors named "Zhan Qi Li"
Acute lymphoblastic leukemia (ALL) is a common pediatric cancer. The second malignant neoplasms (SMNs) in long-term survivors of pediatric ALL are relatively rare. Herein we report a 10-year-old girl who was diagnosed as primitive neuroectodermal tumor (PNET) 5 years after the initial diagnosis of ALL with radiotherapy-free treatment.
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- The study aimed to analyze the clinical and pathological characteristics of splenic B-cell marginal zone lymphoma (SMZL) in patients and its manifestations in bone marrow.
- The researchers reviewed data from 22 patients, noting significant findings like the presence of villous lymphocytes and varying degrees of lymphocytosis in peripheral blood and bone marrow.
- The investigation concluded that overlapping patterns of bone marrow involvement exist in SMZL and emphasizes the need for careful differentiation from other B-cell lymphomas due to shared histological and immunophenotypic features.
[The role of bone marrow pathology in diagnosis and differential diagnosis of refractory cytopenia of children].
Zhonghua Xue Ye Xue Za Zhi
December 2012
Objective: To explore the diagnosis and differential diagnosis of refractory cytopenia of children (RCC) according to WHO classification, and discuss the relationship between the cytology reviewed by hematologists and histology reviewed by pathologists.
Methods: We selected 50 non-severe aplastic anemia cases from 2007 - 2010 in our hospital and collected clinical data. Experienced hematologists and pathologists evaluated bone marrow biopsy and smear respectively.
[Hematopathologic features of T-cell large granular lymphocytic leukemia].
Zhonghua Bing Li Xue Za Zhi
April 2012
Article Synopsis
- The study aimed to investigate the hematopathologic features of T-cell large granular lymphocytic leukemia (T-LGLL) through a retrospective analysis of 19 patients.
- Significant findings included high occurrences of anemia and neutropenia, with large granular lymphocytes identified in most blood and bone marrow samples along with lymphocytosis in the majority of cases.
- The research highlighted distinct hematopathologic features of T-LGLL, emphasizing the importance of thorough morphological, immunophenotypic, and molecular analyses for accurate diagnosis and differentiation of this leukemia type.
[Clinicopathologic features of aggressive natural killer cell leukemia].
Zhonghua Bing Li Xue Za Zhi
December 2011
Objective: To study the clinicopathologic features of aggressive natural killer cell leukemia (ANKL).
Methods: The clinical and pathologic features were analyzed in 10 patients with ANKL. The complete blood count, peripheral blood smears, bone marrow aspirates and bone marrow biopsies were studied.
Objective: To explore the clinicopathologic features of lymphoplasmacytic lymphomas (LPL).
Methods: Routine histological examination was performed on hematoxylin-eosin stained sections of 24 bone marrow biopsies and available 6 concurrent lymph node specimens. Immunohistochemistry study was performed using EliVision methods.
[Clinicopathologic study of 15 splenectomy specimens of patients with hairy cell leukemia].
Zhonghua Bing Li Xue Za Zhi
November 2009
Objective: To investigate the clinicopathologic features, diagnosis, differential diagnosis and the prognosis of hairy cell leukemia (HCL).
Methods: Fifteen splenectomy specimens of HCL patients were investigated retrospectively using HE and immunohistochemistry in correlation with the follow-up information.
Results: (1) The male to female ratio was 2.
The objective of this study was to investigate the ultrastructural characteristics of hybrid acute leukemia (HAL). Fifteen cases of HAL were studied by transmission electron microscopy (TEM), focusing on organelles and myeloperoxidase (MPO) reaction of leukemic cells. By TEM, 5 out 15 cases of HAL were consistent with immunophenotyping (3 cases of biphenotypic type, and 2 cases of biclonal type with granulocytes and lymphocytes); 2 cases were suspected as HAL.
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