Publications by authors named "Zhan Ma"

Article Synopsis
  • - Colorectal cancer (CRC) is a major health concern globally, with miR-137 identified as a crucial tumor suppressor that is often silenced through methylation and H3K27 trimethylation by EZH2.
  • - Research indicates that the frequent methylation of miR-137 in CRC is linked to decreased expression, which can be reversed, enhancing its potential as a therapeutic target.
  • - miR-137 plays a significant role in inhibiting CRC cell behavior and regulates the Wnt signaling pathway by targeting RNF4, ultimately leading to destabilization of key proteins like c-Myc and β-catenin, which are involved in tumor growth.
View Article and Find Full Text PDF

(), a prevalent respiratory pathogen affecting children and adolescents, is known to trigger periodic global epidemics. The most recent significant outbreak commenced in the first half of 2023 and reached its peak globally during the autumn and winter months. Considering the worldwide repercussions of the COVID-19 pandemic, it has become increasingly essential to delve into the epidemiological characteristics of both before and after the pandemic.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how RSV (Respiratory Syncytial Virus) prevalence patterns in China were affected during the COVID-19 pandemic from 2019 to 2022.
  • It analyzed data from over 872,000 children and found that while RSV detection rates rose during the pandemic, especially in children under 5, a notable decline occurred in 2022.
  • The research concludes that the pandemic disrupted typical RSV seasonal patterns, resulting in increased year-long outbreaks and a lack of clear seasonal trends post-April 2022.
View Article and Find Full Text PDF

The development of high-performance specific sensors is promising for the rapid detection of harmful residues in animal-derived foods. Recently, luminescent metal-organic framework/molecularly imprinted polymer (LMOF/MIP) materials have been developed as ideal candidates for the analysis of harmful residues. Here, we reported a simple fabrication protocol of paper-based chip through in-situ growth of LMOF on a negatively charged modified filter paper, a paper-based molecularly imprinting layer (FP@BA-Eu@MIP) was thereafter successfully prepared via the boronate affinity-based controllable oriented surface imprinting strategy.

View Article and Find Full Text PDF

A universal multiscale conditional coding framework, Unicorn, is proposed to compress the geometry and attribute of any given point cloud. Geometry compression is addressed in Part I of this paper, while attribute compression is discussed in Part II. We construct the multiscale sparse tensors of each voxelized point cloud frame and properly leverage lower-scale priors in the current and (previously processed) temporal reference frames to improve the conditional probability approximation or content-aware predictive reconstruction of geometry occupancy in compression.

View Article and Find Full Text PDF

A universal multiscale conditional coding framework, Unicorn, is proposed to code the geometry and attribute of any given point cloud. Attribute compression is discussed in Part II of this paper, while geometry compression is given in Part I of this paper. We first construct the multiscale sparse tensors of each voxelized point cloud attribute frame.

View Article and Find Full Text PDF

Myocardial motion tracking stands as an essential clinical tool in the prevention and detection of cardiovascular diseases (CVDs), the foremost cause of death globally. However, current techniques suffer from incomplete and inaccurate motion estimation of the myocardium in both spatial and temporal dimensions, hindering the early identification of myocardial dysfunction. To address these challenges, this paper introduces the Neural Cardiac Motion Field (NeuralCMF).

View Article and Find Full Text PDF

Tumor microenvironment (TME) is closely associated with the progression and prognosis of head and neck squamous cell carcinoma (HNSCC). To investigate potential biomarkers for predicting therapeutic outcomes in HNSCC, we analyzed the immune and stromal status of HNSCC based on the genes associated with TME using the ESTIMATE algorithm. Immune and stromal genes were identified with differential gene expression and weighted gene co-expression network analysis (WGCNA).

View Article and Find Full Text PDF

The emergence of holographic media drives the standardization of Geometry-based Point Cloud Compression (G-PCC) to sustain networked service provisioning. However, G-PCC inevitably introduces visually annoying artifacts, degrading the quality of experience (QoE). This work focuses on restoring G-PCC compressed point cloud attributes, e.

View Article and Find Full Text PDF

Implicit neural representation (INR) characterizes the attributes of a signal as a function of corresponding coordinates which emerges as a sharp weapon for solving inverse problems. However, the expressive power of INR is limited by the spectral bias in the network training. In this paper, we find that such a frequency-related problem could be greatly solved by re-arranging the coordinates of the input signal, for which we propose the disorder-invariant implicit neural representation (DINER) by augmenting a hash-table to a traditional INR backbone.

View Article and Find Full Text PDF

Conventional cameras capture image irradiance (RAW) on a sensor and convert it to RGB images using an image signal processor (ISP). The images can then be used for photography or visual computing tasks in a variety of applications, such as public safety surveillance and autonomous driving. One can argue that since RAW images contain all the captured information, the conversion of RAW to RGB using an ISP is not necessary for visual computing.

View Article and Find Full Text PDF

It is attractive to use an optical nanorouter by artificial nanostructures to substitute the traditional Bayer filter for an image array sensor, which, however, poses great challenges in balancing the design strategy and the ease of fabrication. Here, we implement and compare two inverse design schemes for rapid optimization of RGGB Bayer-type optical nanorouter. One is based on the multiple Mie scattering theory and the adjoint gradient that is applicable to arrays of nanospheres with varying sizes, and the other is based on the rigorous coupled wave analysis and the genetic algorithm.

View Article and Find Full Text PDF

The lossy Geometry-based Point Cloud Compression (G-PCC) inevitably impairs the geometry information of point clouds, which deteriorates the quality of experience (QoE) in reconstruction and/or misleads decisions in tasks such as classification. To tackle it, this work proposes GRNet for the geometry restoration of G-PCC compressed large-scale point clouds. By analyzing the content characteristics of original and G-PCC compressed point clouds, we attribute the G-PCC distortion to two key factors: point vanishing and point displacement.

View Article and Find Full Text PDF

This paper addresses the problem of lossy image compression, a fundamental problem in image processing and information theory that is involved in many real-world applications. We start by reviewing the framework of variational autoencoders (VAEs), a powerful class of generative probabilistic models that has a deep connection to lossy compression. Based on VAEs, we develop a new scheme for lossy image compression, which we name quantization-aware ResNet VAE (QARV).

View Article and Find Full Text PDF

Advances in both lossy image compression and semantic content understanding have been greatly fueled by deep learning techniques, yet these two tasks have been developed separately for the past decades. In this work, we address the problem of directly executing semantic inference from quantized latent features in the deep compressed domain without pixel reconstruction. Although different methods have been proposed for this problem setting, they either are restrictive to a specific architecture, or are sub-optimal in terms of compressed domain task accuracy.

View Article and Find Full Text PDF

It has been proposed that tumorigenicity was an intrinsic feature of embryonic/germ cell developmental axis as well as embryonic/germ cell-related genes play a crucial role in tumorigenicity. Our previous studies indicated that primordial germ cell (PGC)-like potential could be reactivated in tumorigenesis. In this study, 4T1, 168FARN and 67NR cells which originated from the same mouse breast cancer were studied and the results indicated that the acquisition of embryonic/germ cell-like state is essential for tumorigenicity.

View Article and Find Full Text PDF

As a perennial woody plant, the rubber tree (Hevea brasiliensis) must adapt to various environmental challenges through gene expression in multiple cell types. It is still unclear how genes in this species are expressed at the cellular level and the precise mechanisms by which cells respond transcriptionally to environmental stimuli, especially in the case of pathogen infection. Here, we characterized the transcriptomes in Hevea leaves during early powdery mildew infection using single-cell RNA sequencing.

View Article and Find Full Text PDF
Article Synopsis
  • * Traditional tests like RT-PCR are time-consuming and require lab facilities, while a new point-of-care SERS (Surface-Enhanced Raman Scattering) detection platform can identify the virus in just 5 minutes using a handheld device.
  • * This new method targets the SARS-CoV-2 spike protein and accurately detects the virus and its variants without interfering with other coronaviruses or influenza A, making it a strong candidate for rapid diagnostic use.
View Article and Find Full Text PDF

This study develops a unified Point Cloud Geometry (PCG) compression method through the processing of multiscale sparse tensor-based voxelized PCG. We call this compression method SparsePCGC. The proposed SparsePCGC is a low complexity solution because it only performs the convolutions on sparsely-distributed Most-Probable Positively-Occupied Voxels (MP-POV).

View Article and Find Full Text PDF

Background: It is unclear which core events drive the malignant progression of gliomas. Earlier studies have revealed that the embryonic stem (ES) cell/early PGC state is associated with tumourigenicity. This study was designed to investigate the role of ES/PGC state in poor outcomes of gliomas.

View Article and Find Full Text PDF

In this article, we propose a new distortion quantification method for point clouds, the multiscale potential energy discrepancy (MPED). Currently, there is a lack of effective distortion quantification for a variety of point cloud perception tasks. Specifically, in human vision tasks, a distortion quantification method is used to predict human subjective scores and optimize the selection of human perception task parameters, such as dense point cloud compression and enhancement.

View Article and Find Full Text PDF

Lensless imaging has emerged as a robust means for the observation of microscopic scenes, enabling vast applications like whole-slide imaging, wave-front detection and microfluidic on-chip imaging. Such system captures diffractive measurements in a compact optical setup without the use of optical lens, and then typically applies phase retrieval algorithms to recover the complex field of target object. However existing techniques still suffer from unsatisfactory performance with noticeable reconstruction artifacts especially when the imaging parameter is not well calibrated.

View Article and Find Full Text PDF

One of the most intriguing phenomena in active matter has been the gas-liquid-like motility-induced phase separation (MIPS) observed in repulsive active particles. However, experimentally, no particle can be a perfect sphere, and the asymmetric shape, mass distribution, or catalysis coating can induce an active torque on the particle, which makes it a chiral active particle. Here, using computer simulations and dynamic mean-field theory, we demonstrate that the large enough torque of circle active Brownian particles in two dimensions generates a dynamical clustering state interrupting the conventional MIPS.

View Article and Find Full Text PDF

This work proposes the neural reference synthesis (NRS) to generate high-fidelity reference block for motion estimation and motion compensation (MEMC) in inter frame coding. The NRS is comprised of two submodules: one for reconstruction enhancement and the other for reference generation. Although numerous methods have been developed in the past for these two submodules using either handcrafted rules or deep convolutional neural network (CNN) models, they basically deal with them separately, resulting in limited coding gains.

View Article and Find Full Text PDF

are gram-negative intracellular bacteria; certain species of can cause diseases in mammals and humans. Ticks play a major role in the transmission of . Xinjiang is the largest province in China according to land area and has one-third of the tick species in China; the infection rate of in ticks in the Xinjiang border areas has not been studied in detail.

View Article and Find Full Text PDF