Publications by authors named "Zhala Gasimova"
Front Oncol
September 2024
Article Synopsis
- - Tenosynovial giant cell tumor (TGCT) is a rare tumor that arises from the synovium in joints and tendon sheaths, often associated with genetic changes involving the CSF1 gene; symptoms like pain and swelling are common but not specific, requiring MRI and biopsy for accurate diagnosis.
- - A case study of a 45-year-old man initially diagnosed with Erdheim-Chester disease was later correctly identified as TGCT through whole exome sequencing, which showed a CSF1::GAPDHP64 fusion; he was treated successfully with pegylated interferon and imatinib, stabilizing his condition.
- - Single-cell transcriptome analysis highlighted seven cell clusters and revealed that neoplastic cells attract macroph
