A single-photon emitter coupled to a phononic-crystal resonator in the resolved-sideband regime.

A promising route towards the deterministic creation and annihilation of single-phonons is to couple a single-photon emitter to a mechanical resonator. The challenge lies in reaching the resolved-sideband regime with a large coupling rate and a high mechanical quality factor. We achieve this by coupling self-assembled InAs quantum dots to a small mode-volume phononic-crystal resonator with mechanical frequency Ω/2π = 1.

ctDNA Hypermethylation is a Prognostic Indicator in EGFR-TKI-Treated Advanced Non-Small Cell Lung Cancer.

Purpose: DNA methylation plays a regulatory role in the oncogenesis and tumor progression and is valuable in the diagnosis and prognosis of cancer. While circulating tumor DNA (ctDNA) is widely used in the detection of oncogenic mutations and the guidance of treatment in advanced non-small cell lung cancer (NSCLC), studies of ctDNA methylation remains insufficient. We aim to investigate the methylation profiles of ctDNA in patients with advanced NSCLC undergoing EGFR-tyrosine kinase inhibitor (EGFR-TKI) therapy and to discover novel biomarkers with predictive or prognostic value.

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Fluoroalkyl-grafted polyoxometalate nanoclusters are used as supramolecular additives to precisely modify the ionic domains of Nafion, which can increase the proton conductivity and selectivity simultaneously. The resulting hybrid membranes show significantly enhanced power density in fuel cells and improved energy efficiency in vanadium flow batteries.

Enhanced Electron-Spin Coherence in a GaAs Quantum Emitter.

A spin-photon interface should operate with both coherent photons and a coherent spin to enable cluster-state generation and entanglement distribution. In high-quality devices, self-assembled GaAs quantum dots are near-perfect emitters of on-demand coherent photons. However, the spin rapidly decoheres via the magnetic noise arising from the host nuclei.

Different policies constrained agricultural non-point pollutants emission trading management for water system under interval, fuzzy, and stochastic information.

Formulating suitable policies is essential for resources and environmental management. In this study, an agricultural pollutants emission trading management model driven by water resources and pollutants control is developed to search reasonable policies for agricultural water resources allocation under multiple uncertainties. Random-fuzzy and interval information in water resources system that have directly impact on the effectiveness of management schemes is reflected through interval two-stage stochastic fuzzy-probability programming.

Self-Assembled Construction of Ion-Selective Nanobarriers in Electrolyte Membranes for Redox Flow Batteries.

Ion-conducting membranes (ICMs) with high selectivity are important components in redox flow batteries. However it is still a challenge to break the trade-off between ion conductivity and ion selectivity, which can be resolved by the regulation of their nanostructures. Here, polyoxometalate (POM)-hybridized block copolymers (BCPs) are used as self-assembled additives to construct proton-selective nanobarriers in the ICM matrix to improve the microscopic structures and macroscopic properties of ICMs.

Exosome from adipose-derived mesenchymal stem cells attenuates scar formation through microRNA-181a/SIRT1 axis.

Pathological scarring is the greatest challenge after injury. Exosome from adipose-derived mesenchymal stem cells has been reported effective to improve hypertrophic scar. This study focused on the possible mechanisms during this process.

Effects of hydrothermal factors and human activities on the vegetation coverage of the Qinghai-Tibet Plateau.

A systematic understanding of the spatio-temporal changes and driving factors in the Qinghai-Tibet Plateau holds significant scientific reference value for the future of ecological sustainable development. This paper utilizes MODIS normalized difference vegetation index (NDVI) and meteorological data to investigate the spatio-temporal changes and driving factors of vegetation coverage in the Qinghai-Tibet Plateau from 2001 to 2020. Methods employed include the dimidiate pixel model, trend analysis, partial correlation analysis, and residual analysis.

Semi-Solid Supramolecular Ionic Network Electrolytes Formed by Zwitterionic Liquids and Polyoxometalate Nanoclusters for High Proton Conduction.

Flexible electrolytes with solid self-supporting properties are highly desired in the fields of energy and electronics. However, traditional flexible electrolytes prepared by doping ionic liquids or salt solutions into a polymer matrix pose a risk of liquid component leakage during device operation. In this work, the development of supramolecular ionic network electrolytes using polyoxometalate nanoclusters as supramolecular crosslinkers to solidify bola-type zwitterionic liquids is reported.

Ionic-Nanophase Hybridization of Nafion by Supramolecular Patching for Enhanced Proton Selectivity in Redox Flow Batteries.

Nafion, as the mostly used proton exchange membrane material in vanadium redox flow batteries (VRFBs), encounters serious vanadium permeation problems due to the large size difference between its anionic nanophase (3-5 nm) and cationic vanadium ions (∼0.6 nm). Bulk hybridization usually suppresses the vanadium permeation at the expense of proton conductivity since conventional additives tend to randomly agglomerate and damage the nanophase continuity from unsuitable sizes and intrinsic incompatibility.

Supramolecular Anchoring of Polyoxometalate Amphiphiles into Nafion Nanophases for Enhanced Proton Conduction.

Advanced proton exchange membranes (PEMs) are highly desirable in emerging sustainable energy technology. However, the further improvement of commercial perfluorosulfonic acid PEMs represented by Nafion is hindered by the lack of precise modification strategy due to their chemical inertness and low compatibility. Here, we report the robust assembly of polyethylene glycol grafted polyoxometalate amphiphile (GSiW) into the ionic nanophases of Nafion, which largely enhances the comprehensive performance of Nafion.

Water-carbon nexus relationship and interaction mechanism analysis within Beijing-Tianjin-Hebei urban agglomeration.

As the total water resources consumption control and carbon mitigation continuous improvement, the weak water-carbon incorporate management is increasingly exposed. In this study, a water-carbon nexus assessment framework is proposed to analyze the nexus relationship between water consumption and carbon emission, and distinguishes the coupled water-carbon transmission intensity and the transfer paths under regional and industrial scales. According to the practical input-output table, water consumption, and carbon emission information, the framework is applied to Beijing-Tianjin-Hebei urban agglomeration (BTHUA), a population, resource, and trade intensive area of China.

Dynamic Distribution Characteristics of Oil and Water during Water Flooding in a Fishbone Well with Different Branch Angles.

Lab experiments, field pilots, and numerical modeling focusing on fluid flow aspects have indicated that multi-branch wells are technically effective and promising. Several researchers have conducted some experiments for a fishbone well strategy with mixed results. Our objective in this work is to study the impact of the different fishbone well patterns, such as branch angle, on the distribution of remaining oil after water flooding.

Clinical Efficacy, Healing Efficacy, and Safety Analysis of Skin Orbicularis Oculi Muscle Combined with Tissue Flap for Eyelid Trauma.

This study investigates the efficacy, healing efficiency, and safety of skin orbicularis oculi muscle combined with tissue flap repair for eyelid trauma patients. According to the different methods of surgical intervention, this study chooses 78 cases of eyelid injury patients. This study sets up the joint intervention group and the routine repair group, including the joint intervention group adopting the orbicularis oculi muscle skin of composite tissue flap to repair surgery.

Quantum interference of identical photons from remote GaAs quantum dots.

Photonic quantum technology provides a viable route to quantum communication, quantum simulation and quantum information processing. Recent progress has seen the realization of boson sampling using 20 single photons and quantum key distribution over hundreds of kilometres. Scaling the complexity requires architectures containing multiple photon sources, photon counters and a large number of indistinguishable single photons.

Multi-Step Attack Detection Based on Pre-Trained Hidden Markov Models.

Currently, hidden Markov-based multi-step attack detection models are mainly trained using the unsupervised Baum-Welch algorithm. The Baum-Welch algorithm is sensitive to the initial values of model parameters. However, its training uses random or average parameter initialization methods, which frequently results in the model training into a local optimum, thus, making the model unable to fit the alert logs well and thereby reducing the detection effectiveness of the model.

Hybrid Liquid-Crystalline Electrolytes with High-Temperature-Stable Channels for Anhydrous Proton Conduction.

Modern electrochemical and electronic devices require advanced electrolytes. Liquid crystals have emerged as promising electrolyte candidates due to their good fluidity and long-range order. However, the mesophase of liquid crystals is variable upon heating, which limits their applications as high-temperature electrolytes, e.

Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.

Random-pattern skin flap is a vital technique frequently applied in reconstruction surgeries for its convenience and effectiveness in solving skin defects. However, ischemic necrosis, especially in the distal areas of the flap, still needs extra attention after surgery. Earlier evidence has suggested that paeoniflorin (PF) could stimulate angiogenesis and suppress ischemic cardiovascular disease.

Optically driving the radiative Auger transition.

In a radiative Auger process, optical decay leaves other carriers in excited states, resulting in weak red-shifted satellite peaks in the emission spectrum. The appearance of radiative Auger in the emission directly leads to the question if the process can be inverted: simultaneous photon absorption and electronic demotion. However, excitation of the radiative Auger transition has not been shown, neither on atoms nor on solid-state quantum emitters.

Charge Tunable GaAs Quantum Dots in a Photonic n-i-p Diode.

In this submission, we discuss the growth of charge-controllable GaAs quantum dots embedded in an n-i-p diode structure, from the perspective of a molecular beam epitaxy grower. The QDs show no blinking and narrow linewidths. We show that the parameters used led to a bimodal growth mode of QDs resulting from low arsenic surface coverage.

Anxiety, Loneliness, Drug Craving, and Depression Among Substance Abusers in Sichuan Province, China.

Studies have reported that anxiety had a positive effect on depression among substance abusers in males. However, little is known about the mechanism underlying this relationship in substance abusers in males. The purpose of this study was to investigate the mediating effect of loneliness and drug craving between anxiety and depression in substance abusers in males.

Personality Traits, Loneliness, and Affect Among Boxers.

This study aimed to test the association between personality traits and affect among boxers and to figure out whether loneliness mediated this relationship. This study used The Big Five Personality Traits Scale, The UCLA Loneliness Scale, and The Positive and Negative Affect Scale (PANAS) which were administered to = 231 boxers (age: M = 20.28; = 2.