Efficacy and safety of laparoscopic common bile duct exploration with primary closure and intraoperative endoscopic nasobiliary drainage for choledocholithiasis combined with cholecystolithiasis.

Background: The need for intraoperative endoscopic nasobiliary drainage during laparoscopic cholecystectomy and laparoscopic common bile duct exploration with primary closure is controversial in the treatment of cholecystolithiasis combined with choledocholithiasis. The aim of this study was to evaluate the safety and efficacy of laparoscopic cholecystectomy + laparoscopic common bile duct exploration + intraoperative endoscopic nasobiliary drainage + primary closure (LC + LCBDE + IO-ENBD + PC). The safety of different intubation methods in IO-ENBD was also evaluated.

Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones.

This study aimed to investigate the value of multidisciplinary team (MDT) management in minimally invasive treatment of complex intrahepatic bile duct stones (IHDs) by laparoscopy, choledochoscopy and percutaneous choledochoscopy. The characteristics, perioperative index, complication rate and minimally invasive rate of patients in MDT group (n = 75) and non-MDT group (n = 70) were compared. The members of MDT include doctors in ultrasound, imaging, hepatobiliary and pancreatic surgery, anaesthesia and intensive care medicine.

Widespread deep seismicity in the Delaware Basin, Texas, is mainly driven by shallow wastewater injection.

Industrial activity away from plate boundaries can induce earthquakes and has evolved into a global issue. Much of the induced seismicity in the United States' midcontinent is attributed to a direct pressure increase from deep wastewater disposal. This mechanism is not applicable where deep basement faults are hydraulically isolated from shallow injection aquifers, leading to a debate about the mechanisms for induced seismicity.

Prognostic value of preoperative hematological markers combined with molecular pathology in patients with diffuse gliomas.

The prediction of clinical outcome for patients with infiltrative gliomas is challenging. Although preoperative hematological markers have been proposed as predictors of survival in glioma and other cancers, systematic investigations that combine these data with other relevant clinical variables are needed to improve prognostic accuracy and patient outcomes. We investigated the prognostic value of preoperative hematological markers, alone and in combination with molecular pathology, for the survival of 592 patients with Grade II-IV diffuse gliomas.

Pore-pressure diffusion, enhanced by poroelastic stresses, controls induced seismicity in Oklahoma.

Induced seismicity linked to geothermal resource exploitation, hydraulic fracturing, and wastewater disposal is evolving into a global issue because of the increasing energy demand. Moderate to large induced earthquakes, causing widespread hazards, are often related to fluid injection into deep permeable formations that are hydraulically connected to the underlying crystalline basement. Using injection data combined with a physics-based linear poroelastic model and rate-and-state friction law, we compute the changes in crustal stress and seismicity rate in Oklahoma.