[Pulmonary cytotoxicity induced by bleomycin and methotrexate].

Early detection of drug-induced pulmonary parenchymal injuries is often hampered by nonspecific clinical and X-ray manifestations. The diagnosis is usually based on a history of drug use, clinical and X-ray presentation, and exclusion of other causes of lung tissue injury. Chemical preparations most commonly cause pathological pulmonary changes.

[ANCA-associated vasculitis affecting lungs and kidneys: clinical and morphological characteristic, treatment, outcomes].

Up to 80% of all cases of pulmonary-renal syndrome are due to systemic vasculitis associated with antibodies to neutrophil cytoplasm (ANCA). Most patients die within the first year after the onset of the disease but adequate immunosuppressive therapy ensures the 5-year survival rate of 65-75%. We obtained clinical and morphological data for 34 patients with ANCA-associated vasculitis affecting lungs and kidneys treated at S.

[Diagnostics of cavitary processes in the lungs].

The paper concerns CT-semiotics of cavitary processes in the lungs. Their major forms are discussed with reference to underlying pathological changes. The most common manifestations of the diseases associated with the cavitary processes are described.

[Single-photon emission-computed tomography in evaluation of cerebral microcirculation of patients with epileptiform syndrome].

One-photon emission computed tomography (OPECT) was used to examine 87 patients with the epileptiform syndrome. Eighty five patients had impaired drug distribution which was suggestive of varying degree cerebral circulatory disorders. OPECT with a Tc-99m-gm-pao used in patients with the epileptiform syndrome revealed the morphological substract of brain structures.