[Diagnostic and prognostic significance of the antibodies to the myelin basic protein in acute neuroinfections in children].

The development of severe CNS damages including encephalitis is highly probable in some respiratory and exanthemata viral infections (measles, rubella, parotitis). A high level of IgG antibodies to the myelin basic protein was found in patients with parotitis meningitis and rubella encephalitis but it was not high in 80% of patients with encephalitis of the unclear etiology and in 25% of cases with rubella encephalitis. More accurate analysis of clinical, neurovisual and immunologic data revealed a link of appearance of such complications with both the presence of more pronounced demyelinization and prolongation of the disease.

[The characteristics of the specific immune response in vaccinated children in an area of high endemicity for viral hepatitis B].

The effectiveness of vaccination against virus hepatitis B (VHB) in the arid region of the Aral, endemic with respect to VHB, was evaluated. The character of specific immune response in 101 immunized children and in 12 adults belonging to a high risk group with respect to VHB. The vaccination of children was shown to be highly effective (96%).