Klin Lab Diagn
February 2008
The present study was undertaken to examine the state of intracellular components and leukocytes and the role of the lipid peroxidation (LPO) system and antioxidative defense (AOD) in the pathogenesis of HIV infection. The parameters of the enzymatic link of the antioxidative system and LPO processes and leukocytic intracellular components in 108 patients with HIV infection are presented. In the HIV-infected patients, the state of intracellular components of leukocytes showed a heterodirectional pattern.
View Article and Find Full Text PDFAim: To study lipid peroxidation (LPO) and anti-oxidant system (AOS) in patients with HIV infection.
Material And Methods: Enzymatic parameters of AOS and LPO were studied in 108 patients with HIV infection, 38 of them had HIV+HBV, HIV+HCV infection and 17 patients had associated tuberculosis.
Results: Severe alterations of LPO were found: a significant rise of LPO products, malonic dialdehyde and dienic conjugates.