[Antihypertensive treatment compliance and obstacles to its improvement. Results of Russian program ARGUS-2].

Aim: To study barriers made by the patients for adequate treatment of arterial hypertension.

Material And Methods: The ARGUS-2 trial was made in 15 centers of 13 cities of Russia. Anonymous questionnaire survey covered 1298 patients (796 outpatients and 502 inpatients).

[Alcohol-induced arterial hypertension and genetic polymorphism of alcohol-metabolizing enzymes].

Aim: To study arterial pressure (AP) and heart rate (HR) in patients suffering from alcohol withdrawal syndrome (AWS) with relation to genetic polymorphism of alcohol dehydrogenase-2 (ADG2) and aldehyde dehydrogenase-2 (AlDG2).

Material And Methods: AP and HR were analysed for 36 alcoholics (83 hospitalizations, including repeated ones) with genotypes ADG2 and AIDG2 at admission to and discharge from narcological hospital.

Results: ADG2 genotypes distribution was the following: ADG2-1/1--61.

[Clinical and demographic characteristics of various types of arterial hypertension in elderly patients (based on results of Russian scientific-practical program ARGUS].

Aim: It is the fragment of the trial aimed at the study of demographic indices and components of cardiovascular risk in patients over 55 with known and newly diagnosed arterial hypertension (AH) by referral to outpatient clinic depending on AH type.

Material And Methods: For a week, 140 therapists from 14 regions of the Russian Federation measured AP in all persons aged 55 and older visiting outpatient clinics. A total of 5582 persons were examined.

[Polymorphism of vascular angiotensin II receptor gene and cardiovascular disorders].

Aim: To study polymorphism of the gene of vascular angiotensin II receptor.

Materials And Methods: Polymorphism that consists in variability of adenine (A) and cytosine (C) residues at position 1166 of the gene for vascular angiotensin II receptor (AT1R) was analyzed in a Moscow population (n = 98) and three groups of affected patients with myocardial infarction (n = 32, MI), left ventricular hypertrophy (LVH, n = 38) and essential hypertension (EH, n = 178). Polymorphic region of the AT1R gene was amplified using the polymerase chain reaction (PCR) and genomic DNAs from human whole blood as template.

[Changes in blood pressure 24 hour monitoring data and quality of life in patients with systolic hypertension treated with arifon].

Aim: The study of quality of life and 24-h monitoring blood pressure data in elderly patients with isolated systolic hypertension (SH) on arifon monotherapy.

Materials And Methods: 22 patients over 65 (mean age 69.8 +/- 1.

[Change of circadian pattern of arterial pressure in patients with congestive heart failure treated with perindopril, an inhibitor of angiotensin-converting enzyme (ACE)].

The 24-h profile of blood pressure (BP) was studied in 28 patients (21 males and 7 females) with congenital heart failure (CHF) of NYHA class II-III (ejection fraction < 45%). The patients were 46 to 76 years of age and had postinfarction cardiosclerosis. They had not received ACE inhibitors before.